| Entry |
|
|---|
| Name |
globoside alpha-N-acetylgalactosaminyltransferase;
uridine diphosphoacetylgalactosamine-globoside
alpha-acetylgalactosaminyltransferase;
Forssman synthase;
globoside acetylgalactosaminyltransferase;
UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-
galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
alpha-N-acetyl-D-galactosaminyltransferase |
|---|
| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
 |
|---|
| Sysname |
UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-(1->3)-D-gala
ctosyl-(1->4)-D-galactosyl-(1->4)-D-glucosyl-(11)-ceramide
alpha-N-acetyl-D-galactosaminyltransferase |
|---|
| Reaction(IUBMB) |
UDP-N-acetyl-D-galactosamine +
N-acetyl-D-galactosaminyl-(1->3)-D-galactosyl-(1->4)-D-galactosyl-
(1->4)-D-glucosyl-(11)-ceramide = UDP +
N-acetyl-D-galactosaminyl-(1->3)-N-acetyl-D-galactosaminyl-(1->3)-D-
galactosyl-(1->4)-D-galactosyl-(1->4)-D-glucosyl-(11)-ceramide
[RN:R04182 R05965] |
|---|
| Reaction(KEGG) |
R04182 R05965(G)
 |
|---|
| Substrate |
UDP-N-acetyl-D-galactosamine [CPD:C00203];
N-acetyl-D-galactosaminyl-(1->3)-D-galactosyl-(1->4)-D-galactosyl-
(1->4)-D-glucosyl-(11)-ceramide |
|---|
| Product |
UDP [CPD:C00015];
N-acetyl-D-galactosaminyl-(1->3)-N-acetyl-D-galactosaminyl-(1->3)-D-
galactosyl-(1->4)-D-galactosyl-(1->4)-D-glucosyl-(11)-ceramide |
|---|
| Pathway |
PATH: ec00603 Glycosphingolipid biosynthesis - globo series
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00722 globoside alpha-N-acetylgalactosaminyltransferase |
|---|
| Genes |
HSA: 26301(GBGT1)
PTR: 464823(GBGT1)
MMU: 227671(Gbgt1)
CFA: 403833(GBGT1)
BTA: 618517(GBGT1) 783982(GBGT1)
ECB: 100069388
MDO: 100017839
OAA: 100090987
GGA: 417163(GBGT1)
TGU: 100225394
DRE: 387303(gbgt1l4)
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4823436]
Kijimoto S, Ishibashi T, Makita A.
Biosynthesis of Forssman hapten from globoside by
alpha-N-acetylgalactosaminyltransferase of guinea pig tissues.
Biochem. Biophys. Res. Commun. 56 (1974) 177-84.
Cavia porcellus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.4.1.88
IUBMB Enzyme Nomenclature: 2.4.1.88
ExPASy - ENZYME nomenclature database: 2.4.1.88
BRENDA, the Enzyme Database: 2.4.1.88
CAS: 52037-97-5 |
|---|
