KEGG   ENZYME: 2.4.2.20Help
Entry
EC 2.4.2.20                 Enzyme                                 

Name
dioxotetrahydropyrimidine phosphoribosyltransferase;
dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase;
dioxotetrahydropyrimidine phosphoribosyl transferase;
dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase;
2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
BRITE hierarchy
Sysname
2,4-dioxotetrahydropyrimidine-D-ribonucleotide:diphosphate phospho-alpha-D-ribosyltransferase
Reaction(IUBMB)
a 2,4-dioxotetrahydropyrimidine D-ribonucleotide + diphosphate = a 2,4-dioxotetrahydropyrimidine + 5-phospho-alpha-D-ribose 1-diphosphate [RN:R04346]
Reaction(KEGG)
Substrate
2,4-dioxotetrahydropyrimidine D-ribonucleotide [CPD:C04639];
diphosphate [CPD:C00013]
Product
2,4-dioxotetrahydropyrimidine [CPD:C00429];
5-phospho-alpha-D-ribose 1-diphosphate [CPD:C00119]
Comment
Acts (in the reverse direction) on uracil and other pyrimidines and pteridines containing a 2,4-diketo structure.
History
EC 2.4.2.20 created 1972
Reference
1  [PMID:14235538]
  Authors
HATFIELD D, WYNGAARDEN JB.
  Title
3-RIBOSYLPURINES. I. SYNTHESIS OF (3-RIBOSYLURIC ACID) 5'-PHOSPHATE AND (3-RIBOSYLXANTHINE) 5'-PHOSPHATE BY A PYRIMIDINE RIBONUCLEOTIDE PYROPHOSPHORYLASE OF BEEF ERYTHROCYTES.
  Journal
J. Biol. Chem. 239 (1964) 2580-6.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37277-75-1

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