KEGG   ENZYME: 2.4.2.37Help
Entry
EC 2.4.2.37                 Enzyme                                 

Name
NAD+---dinitrogen-reductase ADP-D-ribosyltransferase;
NAD-azoferredoxin (ADPribose)transferase;
NAD-dinitrogen-reductase ADP-D-ribosyltransferase;
draT (gene name)
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
BRITE hierarchy
Sysname
NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase
Reaction(IUBMB)
NAD+ + [dinitrogen reductase]-L-arginine = nicotinamide + [dinitrogen reductase]-Nomega-alpha-(ADP-D-ribosyl)-L-arginine [RN:R03447]
Reaction(KEGG)
Substrate
NAD+ [CPD:C00003];
[dinitrogen reductase]-L-arginine [CPD:C03315]
Product
nicotinamide [CPD:C00153];
[dinitrogen reductase]-Nomega-alpha-(ADP-D-ribosyl)-L-arginine [CPD:C01253]
Comment
The combined action of this enzyme and EC 3.2.2.24, ADP-ribosyl-[dinitrogen reductase] hydrolase, controls the activity level of nitrogenase (EC 1.18.6.1). In the presence of ammonium, the product of nitrogenase, this enzyme covalently links an ADP-ribose moiety to a specific arginine residue of the dinitrogenase reductase component of nitrogenase, blocking its activity.
History
EC 2.4.2.37 created 1992, modified 2015
Orthology
K05951  
NAD+---dinitrogen-reductase ADP-D-ribosyltransferase
Genes
TTU: 
MCA: 
MMT: 
MDN: 
MDH: 
ALV: 
TVI: 
TMB: 
MPUR: 
HHC: 
EBS: 
HAZ: 
GSN: 
TAU: 
SEDS: 
RGE: 
RGE_42860(draT)
RBN: 
AZO: 
azo0537(draT)
AZA: 
AZKH_0793(draT)
AZI: 
DAR: 
DSU: 
APP: 
SLT: 
GSU: 
GSU2802(draT)
GSK: 
GME: 
Gmet_0674(draT)
GUR: 
GLO: 
GBM: 
Gbem_2081(draT)
GEO: 
Geob_2585(draT)
GEM: 
GEB: 
GPI: 
PCA: 
Pcar_2092(draT)
PPD: 
DES: 
DEU: 
DAT: 
AFW: 
ANK: 
RPA: 
RPA1431(draT1) RPA2405(draT2)
RPB: 
RPC: 
RPD: 
RPE: 
RPT: 
RPX: 
BVR: 
RSQ: 
RCP: 
RRU: 
RRF: 
RPM: 
MAG: 
MGY: 
MAGX: 
XM1_3937(draT)
AZL: 
ALI: 
ABS: 
ABQ: 
ATI: 
AHU: 
MGM: 
AFE: 
AFR: 
AFE_1524(draT)
AFI: 
OBT: 
CAA: 
DIN: 
DAP: 
CNI: 
 » show all
Taxonomy
Reference
1  [PMID:3141411]
  Authors
Lowery RG, Ludden PW.
  Title
Purification and properties of dinitrogenase reductase ADP-ribosyltransferase from the photosynthetic bacterium Rhodospirillum rubrum.
  Journal
J. Biol. Chem. 263 (1988) 16714-9.
Reference
2  [PMID:2506427]
  Authors
Fitzmaurice WP, Saari LL, Lowery RG, Ludden PW, Roberts GP.
  Title
Genes coding for the reversible ADP-ribosylation system of dinitrogenase reductase from Rhodospirillum rubrum.
  Journal
Mol. Gen. Genet. 218 (1989) 340-7.
  Sequence
[rru:Rru_A1009]
Reference
3  [PMID:24934999]
  Authors
Moure VR, Costa FF, Cruz LM, Pedrosa FO, Souza EM, Li XD, Winkler F, Huergo LF
  Title
Regulation of nitrogenase by reversible mono-ADP-ribosylation.
  Journal
Curr. Top. Microbiol. Immunol. 384 (2015) 89-106.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
117590-45-1

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