KEGG   ENZYME: 2.4.2.38Help
Entry
EC 2.4.2.38                 Enzyme                                 

Name
glycoprotein 2-beta-D-xylosyltransferase;
beta1,2-xylosyltransferase;
UDP-D-xylose:glycoprotein (D-xylose to the 3,6-disubstituted mannose of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 2-beta-D-xylosyltransferase
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
BRITE hierarchy
Sysname
UDP-D-xylose:glycoprotein (D-xylose to the 3,6-disubstituted mannose of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 2-beta-D-xylosyltransferase
Reaction(IUBMB)
UDP-D-xylose + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine = UDP + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine [RN:R06016]
Reaction(KEGG)
R06016(G)
Show
Substrate
UDP-D-xylose [CPD:C00190];
N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine
Product
UDP [CPD:C00015];
N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine
Comment
Specific for N-linked oligosaccharides (N-glycans).
History
EC 2.4.2.38 created 2001
Pathway
Various types of N-glycan biosynthesis
Orthology
K03714  
glycoprotein 2-beta-D-xylosyltransferase
Genes
HRO: 
LGI: 
ATH: 
AT5G55500(XYLT)
ALY: 
CRB: 
EUS: 
BRP: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0001s37150g(POPTRDRAFT_550155)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os08t0503800-01(Os08g0503800)
OBR: 
BDI: 
SBI: 
SORBI_07g028020(SORBIDRAFT_07g028020)
ZMA: 
732746(xt1)
SITA: 
PDA: 
MUS: 
ATR: 
s00055p00165140(AMTR_s00055p00165140)
SMO: 
PPP: 
CRE: 
 » show all
Taxonomy
Reference
1  [PMID:9395463]
  Authors
Zeng Y, Bannon G, Thomas VH, Rice K, Drake R, Elbein A.
  Title
Purification and specificity of beta1,2-xylosyltransferase, an enzyme that contributes to the allergenicity of some plant proteins.
  Journal
J. Biol. Chem. 272 (1997) 31340-7.
Reference
2  [PMID:10781814]
  Authors
Strasser R, Mucha J, Mach L, Altmann F, Wilson IB, Glossl J, Steinkellner H.
  Title
Molecular cloning and functional expression of beta1, 2-xylosyltransferase cDNA from Arabidopsis thaliana.
  Journal
FEBS. Lett. 472 (2000) 105-8.
  Sequence
[ath:AT5G55500]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
141256-56-6

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