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Entry
EC 2.4.2.46                 Enzyme                                 

Name
galactan 5-O-arabinofuranosyltransferase;
AftA;
Rv3792
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
BRITE hierarchy
Sysname
galactofuranan:trans,octacis-decaprenylphospho-beta-D-arabinofuranose 5-O-alpha-D-arabinofuranosyltransferase
Reaction(IUBMB)
Adds an alpha-D-arabinofuranosyl group from trans,octacis-decaprenylphospho-beta-D-arabinofuranose at the 5-O-position of the eighth, tenth and twelfth galactofuranose unit of the galactofuranan chain of [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
Comment
Isolated from Mycobacterium tuberculosis and Corynebacterium glutamicum. These arabinofuranosyl groups form the start of an arabinofuranan chain as part of the of the cell wall in mycobacteria.
History
EC 2.4.2.46 created 2012
Orthology
K13686  
galactan 5-O-arabinofuranosyltransferase
Genes
MTU: 
Rv3792(aftA)
MTV: 
MTC: 
MRA: 
MTF: 
MTB: 
MTK: 
MTZ: 
MTG: 
MTE: 
MTUR: 
MTL: 
MTO: 
MTD: 
MTN: 
MTJ: 
MTUB: 
MTUE: 
MTX: 
MTUL: 
MBO: 
MBB: 
MBT: 
MBM: 
MBK: 
MAF: 
MCE: 
MCQ: 
MCV: 
MCX: 
MCZ: 
MLE: 
MLB: 
MPA: 
MAO: 
MAV: 
MIT: 
MIR: 
MIA: 
MID: 
MYO: 
MSM: 
MSG: 
MSA: 
MUL: 
MVA: 
MGI: 
MSP: 
MAB: 
MABB: 
MMV: 
MMC: 
MKM: 
MJL: 
MJD: 
MMI: 
MRH: 
MMM: 
MCB: 
MLI: 
MKN: 
MNE: 
CGL: 
NCgl0185(Cgl0188)
CGB: 
CGU: 
WA5_0185(AftA)
CGT: 
CGS: 
CGG: 
CGM: 
CEF: 
CDI: 
CDP: 
CDH: 
CDT: 
CDE: 
CDR: 
CDA: 
CDZ: 
CDB: 
CDS: 
CDD: 
CDW: 
CDV: 
CJK: 
CUR: 
CUA: 
CAR: 
CKP: 
CPU: 
CPL: 
CPG: 
CPP: 
CPK: 
CPQ: 
CPX: 
CPZ: 
COR: 
COP: 
Cp31_0115(aftA)
COD: 
COS: 
COI: 
COE: 
COU: 
CRD: 
CRES_0492(aftA)
CUL: 
CUC: 
CUE: 
CVA: 
CVAR_2886(aftA)
CHN: 
CCN: 
CTER: 
CMD: 
CAZ: 
CFN: 
CCG: 
CVT: 
CGY: 
NFA: 
NCY: 
NBR: 
NNO: 
RHA: 
RER: 
RER_02330(aftA)
REY: 
ROP: 
ROP_39510(aftA)
ROA: 
REQ: 
RPY: 
GBR: 
GPO: 
GOR: 
TPR: 
SRT: 
KSK: 
MMAR: 
SEN: 
CAI: 
 » show all
Taxonomy
Reference
1  [PMID:16595677]
  Authors
Alderwick LJ, Seidel M, Sahm H, Besra GS, Eggeling L
  Title
Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis.
  Journal
J. Biol. Chem. 281 (2006) 15653-61.
  Organism
Corynebacterium glutamicum, Mycobacterium tuberculosis
  Sequence
[cgl:NCgl0185] [mtu:Rv3792]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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