KEGG   ENZYME: 2.4.2.8Help
Entry
EC 2.4.2.8                  Enzyme                                 
Name hypoxanthine phosphoribosyltransferase;
IMP pyrophosphorylase;
transphosphoribosidase;
hypoxanthine---guanine phosphoribosyltransferase;
guanine phosphoribosyltransferase;
GPRT;
HPRT;
guanosine 5'-phosphate pyrophosphorylase;
IMP-GMP pyrophosphorylase;
HGPRTase;
6-hydroxypurine phosphoribosyltransferase;
6-mercaptopurine phosphoribosyltransferase;
GMP pyrophosphorylase;
guanine-hypoxanthine phosphoribosyltransferase;
guanosine phosphoribosyltransferase;
guanylate pyrophosphorylase;
guanylic pyrophosphorylase;
inosinate pyrophosphorylase;
inosine 5'-phosphate pyrophosphorylase;
inosinic acid pyrophosphorylase;
inosinic pyrophosphorylase;
6-mercaptopurine phosphoribosyltransferase;
purine-6-thiol phosphoribosyltransferase
Class Transferases;
Glycosyltransferases;
Pentosyltransferases
BRITE hierarchy
Sysname IMP:diphosphate phospho-D-ribosyltransferase
Reaction(IUBMB) IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose
1-diphosphate [RN:R01132]
Reaction(KEGG) R01132;
(other) R00190 R01229 R02142 R08237 R08238 R08245
Show
Substrate IMP [CPD:C00130];
diphosphate [CPD:C00013]
Product hypoxanthine [CPD:C00262];
5-phospho-alpha-D-ribose 1-diphosphate [CPD:C00119]
Comment Guanine and 6-mercaptopurine can replace hypoxanthine.
Pathway PATH: ec00230  Purine metabolism
PATH: ec00983  Drug metabolism - other enzymes
PATH: ec01100  Metabolic pathways
Orthology KO: K00760  hypoxanthine phosphoribosyltransferase
Genes HSA: 3251(HPRT1)
PTR: 735894(HPRT1)
MCC: 709186
MMU: 15452(Hprt1)
RNO: 24465(Hprt1)
CFA: 442945(HPRT1)
BTA: 281229(HPRT1)
SSC: 397351(HPRT1)
ECB: 100034149(HPRT1)
MDO: 100016863 100017413 100017526 100017665 100017785 100018088
     100025248 554237(HPRT1)
OAA: 791108(HPRT1)
GGA: 395653(HPRT1) 776388
TGU: 100231349
XLA: 446895 779138(prtfdc1)
XTR: 394936(hprt1)
DRE: 406259(hprt1)
CIN: 100183974
CEL: Y105E8B.5
CBR: CBG19800
BMY: Bm1_19890
SMM: Smp_103560 Smp_168500
NVE: NEMVE_v1g131270
HMG: 100205512
ATH: AT1G71750
POP: POPTR_818608
RCU: RCOM_0296600
VVI: 100242653(GSVIVT00005398001)
SBI: SORBI_09g005630(SORBIDRAFT_09g005630)
ZMA: 100281175
PPP: PHYPADRAFT_114087
CME: CME008C
MBR: MONBRDRAFT_37026
DDI: DDB_0216388(hprT)
PFA: PF10_0121
PFH: PFHG_03778
PCB: PC001328.02.0
PBE: PB001303.00.0
PKN: PKH_081190
PVX: PVX_094840
TGO: TGME49_000320
TBR: Tb10.70.6650
TCR: 506457.30 509693.70
LMA: LmjF21.0845
LIF: LinJ12.0120
LBZ: LbrM21_V2.0990
TVA: TVAG_243770
PTI: PHATRDRAFT_35566
ECO: b0125(hpt)
ECJ: JW5009(hpt)
ECD: ECDH10B_0105(hpt)
EBW: BWG_0118(hpt)
ECE: Z0136(hpt)
ECS: ECs0129
ECF: ECH74115_0133(hpt)
ETW: ECSP_0126(hpt)
ECG: E2348C_0128(hpt)
ECC: c0154(hpt)
ECI: UTI89_C0138(hpt)
ECP: ECP_0133
ECV: APECO1_1860(hpt)
ECW: EcE24377A_0127(hpt)
ECX: EcHS_A0129(hpt)
ECM: EcSMS35_0135(hpt)
ECY: ECSE_0125
ECL: EcolC_3534
ECK: EC55989_0118(hpt)
ECQ: ECED1_0129(hpt)
ECR: ECIAI1_0123(hpt)
ECT: ECIAI39_0125(hpt)
ECZ: ECS88_0134(hpt)
EUM: ECUMN_0122(hpt)
ELF: LF82_1031(hpt)
EBL: B21_00123(hpt)
EBD: ECBD_3494
EBR: ECB_00124(hpt)
EOH: ECO103_0125(hpt)
EOI: ECO111_0126(hpt)
EOJ: ECO26_0127(hpt)
EFE: EFER_0146(hpt)
STY: STY0192(hpt)
STT: t0175(hpt)
SPT: SPA0173(hpt)
SEK: SSPA0169
SPQ: SPAB_00209
SEI: SPC_0183(hpt)
SEC: SC0170(hpt)
SEH: SeHA_C0194(hpt)
SEE: SNSL254_A0186(hpt)
SEW: SeSA_A0189(hpt)
SEA: SeAg_B0202(hpt)
SED: SeD_A0185(hpt)
SEG: SG0173(hpt)
SET: SEN0175(hpt)
SES: SARI_02824
STM: STM0170(hpt)
YPE: YPO3408(hpt)
YPK: y0778(hpt)
YPM: YP_0277(hpt)
YPA: YPA_2910
YPN: YPN_0680
YPG: YpAngola_A1019(hpt)
YPP: YPDSF_2947
YPS: YPTB0723(hpt)
YPI: YpsIP31758_3351(hpt)
YPY: YPK_3479
YPB: YPTS_0754
YEN: YE0713(b0125)
SFL: SF0122(hpt)
SFX: S0124(hpt)
SFV: SFV_0116(hpt)
SSN: SSON_0133(hpt)
SBO: SBO_0114(hpt)
SBC: SbBS512_E0118(hpt)
SDY: SDY_0034(hpt)
ECA: ECA3328(hpt)
PCT: PC1_3124
PWA: Pecwa_1154
ETA: ETA_08510(hpt)
PLU: plu0860 plu0864
PAY: PAU_00798(hpt)
BUC: BU195(hpt)
BAS: BUsg189(hpt)
BAP: BUAP5A_192(hpt)
BAU: BUAPTUC7_194(hpt)
SGL: SG0482
ENT: Ent638_0673
ESA: ESA_03207
CTU: Ctu_07640(hpt)
KPN: KPN_00133(hpt)
KPE: KPK_4603(hpt)
KPU: KP1_0960(hpt)
CKO: CKO_03242
SPE: Spro_3998
PMR: PMI0160(hpt)
EIC: NT01EI_0768
ETR: ETAE_0670(hpt)
DDA: Dd703_2829
DDC: Dd586_3148
DZE: Dd1591_1022
HIN: HI1153(hpt)
HIT: NTHI1321(hpt)
HIP: CGSHiEE_06280
HIQ: CGSHiGG_09435
HDU: HD1399(hpt)
HAP: HAPS_0362(hpt)
HSO: HS_0463(hpt)
HSM: HSM_0762
PMU: PM0121(hpt)
MSU: MS0683(hpt)
APL: APL_0682(hpt)
APJ: APJL_0678(hpt)
APA: APP7_0722
ASU: Asuc_0811
AAP: NT05HA_1447
AAT: D11S_2059
XFA: XF2354
XFT: PD1382(hpt)
XFM: Xfasm12_1524
XFN: XfasM23_1467
XCC: XCC1284(hpt)
XCB: XC_2957
XCA: xccb100_3019
XCV: XCV1387(hpt)
XAC: XAC1335(hpt)
XOO: XOO1868(hpt)
XOM: XOO_1763
XOP: PXO_01729
SML: Smlt3537(hpt)
SMT: Smal_2967
VCH: VC0585
VCO: VC0395_A0117(hpt)
VCM: VCM66_0543(hpt)
VCJ: VCD_001024
VVU: VV1_1635 VV1_1636
VVY: VV2769
VPA: VP2515
VHA: VIBHAR_03458
VSP: VS_2538
VEX: VEA_002554
VFI: VF_2176(hpt) VF_A0019
VFM: VFMJ11_2290(hpt)
VSA: VSAL_I2618(hpt)
PPR: PBPRA1638 PBPRA3180
PAE: PA4645
PAU: PA14_61460(hpt)
PAP: PSPA7_5294
PAG: PLES_50311
PPU: PP_0747
PPF: Pput_0775
PPG: PputGB1_0788
PPW: PputW619_4442
PST: PSPTO_1131(hpt)
PSB: Psyr_0970
PSP: PSPPH_1019(hpt)
PFL: PFL_5138
PFO: Pfl01_4727
PFS: PFLU0900
PEN: PSEEN0889
PMY: Pmen_0947
PSA: PST_3174(hpt)
CJA: CJA_3787
AVN: Avin_41350(hpt)
PAR: Psyc_1125(hpt)
PCR: Pcryo_1293
PRW: PsycPRwf_1210
ACI: ACIAD3669(hpt)
ACB: A1S_2974
ABM: ABSDF3674(hpt)
ABY: ABAYE3887(hpt)
ABC: ACICU_00015
ABN: AB57_0031(hpt)
ABB: ABBFA_003522(hpt)
SON: SO_3803(hpt-2)
SDN: Sden_0654
SFR: Sfri_3233
SAZ: Sama_0771
SBL: Sbal_0721
SBM: Shew185_3590
SBN: Sbal195_3713
SBP: Sbal223_3521
SLO: Shew_3142
SPC: Sputcn32_0829
SSE: Ssed_3910
SPL: Spea_0688
SHE: Shewmr4_3145
SHM: Shewmr7_0822
SHN: Shewana3_0793
SHW: Sputw3181_3344
SHL: Shal_0745
SWD: Swoo_3818
SWP: swp_4397
CPS: CPS_1752(hpt)
SDE: Sde_1792
MAQ: Maqu_3593
TTU: TERTU_2039
CBU: CBU_1074
CBS: COXBURSA331_A0858
CBD: CBUD_1176
CBG: CbuG_0930
CBC: CbuK_0938
LPN: lpg1519
LPF: lpl1507(ppt)
LPP: lpp1476(ppt)
LPC: LPC_0938(ppt)
MCA: MCA1985
FTU: FTT_0205(hpt)
FTF: FTF0205(hpt)
FTW: FTW_1883(hpt)
FTL: FTL_1931
FTH: FTH_1851(hpt)
FTA: FTA_2040(hpt)
FTM: FTM_1638(hpt)
FTN: FTN_0179(hpt)
FPH: Fphi_0646
NOC: Noc_0456
AEH: Mlg_1328
HHA: Hhal_1260
TGR: Tgr7_1752
HNA: Hneap_1397
HCH: HCH_00775
CSA: Csal_2065
ABO: ABO_1020(hpt)
MMW: Mmwyl1_1720
AHA: AHA_3546(hpt)
ASA: ASA_0774(hpt)
TAU: Tola_0812
DNO: DNO_0023
AFE: Lferr_0534
AFR: AFE_0364
KKO: Kkor_1684
NMA: NMA0389(hpt)
NME: NMB2047
NMC: NMC2027(hpt)
NMN: NMCC_0139(hpt)
NMI: NMO_0121(hpt)
NGO: NGO2035
NGK: NGK_2201
CVI: CV_3900(hpt)
LHK: LHK_02874(hpt)
RSO: RSc2812(hprT)
RPI: Rpic_3057
RPF: Rpic12D_2647
REU: Reut_A2948
REH: H16_A3242(hprT)
RME: Rmet_3095
CTI: RALTA_A2693
BMA: BMA2515
BMV: BMASAVP1_A0437
BML: BMA10229_A1296
BMN: BMA10247_3267
BPS: BPSL2996
BPM: BURPS1710b_3516
BPL: BURPS1106A_3518
BPD: BURPS668_3480
BPR: GBP346_A3664
BTE: BTH_I1148
BVI: Bcep1808_0565
BUR: Bcep18194_A3674
BCN: Bcen_0107
BCH: Bcen2424_0589
BCM: Bcenmc03_0559
BCJ: BCAL3434
BAM: Bamb_0492
BAC: BamMC406_0517
BMU: Bmul_2794
BMJ: BMULJ_00443(hpt)
BXE: Bxe_A0515
BPH: Bphy_2644
BPY: Bphyt_3441
BGL: bglu_1g04910
NMU: Nmul_A0649
EBA: ebA3304
AZO: azo3670(hpt)
DAR: Daro_1736
TMZ: Tmz1t_0670
TBD: Tbd_0777
MFA: Mfla_1280
MMB: Mmol_1040
MEI: Msip34_1723
APP: CAP2UW1_3628
GSU: GSU1017
GME: Gmet_2716
GUR: Gura_3398
GLO: Glov_1031
GBM: Gbem_0541
GEO: Geob_1621
GEM: GM21_0554
PCA: Pcar_2547(hpt)
PPD: Ppro_3004
DVU: DVU1588(hpt)
DVL: Dvul_1545
DVM: DvMF_0473
DDE: Dde_2112
DDS: Ddes_1440
DMA: DMR_21160(hpt)
DSA: Desal_3658
DBA: Dbac_1856
DRT: Dret_0862
BBA: Bd0122(hprT) Bd3219(hpt)
DPS: DP0449
DOL: Dole_1423
DAL: Dalk_3240
DAT: HRM2_32180(hpt)
ADE: Adeh_0127
ACP: A2cp1_0145
AFW: Anae109_0131
ANK: AnaeK_0134
MXA: MXAN_5070(hpt)
SCL: sce8180(hpt)
HOH: Hoch_3435
SAT: SYN_02450
SFU: Sfum_1422
MLO: mll3520
MES: Meso_3093
PLA: Plav_1597
SME: SMc00719(hpt)
SMD: Smed_2541
ATU: Atu3604(hpt)
ATC: AGR_L_2446
ARA: Arad_4205(hpt)
AVI: Avi_4024(hpt)
RET: RHE_CH03800(hpt)
REC: RHECIAT_CH0004071(hpt)
RLE: RL4328(hprT)
RLT: Rleg2_3570
RLG: Rleg_3863
RHI: NGR_c26990
BME: BMEI0082
BMF: BAB1_1986(hpt)
BMB: BruAb1_1961(hpt)
BMC: BAbS19_I18640
BMS: BR1985(hpt)
BMT: BSUIS_A1825(hpt)
BOV: BOV_1910(hpt)
BCS: BCAN_A2030(hpt)
BMR: BMI_I2008(hpt)
OAN: Oant_0995
XAU: Xaut_0023
AZC: AZC_4610
MEX: Mext_2861
MEA: Mex_1p3063(hpt)
MDI: METDI3629(hpt)
MRD: Mrad2831_3996
MET: M446_2197
MPO: Mpop_2981
MCH: Mchl_3087
MNO: Mnod_1156
CCR: CC_2214
CCS: CCNA_02297
CAK: Caul_3215
PZU: PHZ_c0632(hpt)
SIL: SPO2097(hpt)
SIT: TM1040_1368
RSP: RSP_2786(HPRT)
RSH: Rsph17029_1428
RSQ: Rsph17025_1044
RSK: RSKD131_1092
JAN: Jann_2230
RDE: RD1_2771(hpt)
DSH: Dshi_1581(hpt)
HNE: HNE_3388(hpt)
HBA: Hbal_0235
MGM: Mmc1_0665 Mmc1_3192
BSU: BSU00680(hprT)
BHA: BH0084(hprT)
BAN: BA0063(hpt-1) BA5074(hpt-2)
BAR: GBAA0063(hpt-1) GBAA5074(hpt-2)
BAA: BA_0653 BA_5491
BAT: BAS0063 BAS4712
BAH: BAMEG_0076(hpt) BAMEG_5108(hpt2)
BAI: BAA_0076(hpt) BAA_5085(hpt2)
BCE: BC0071 BC4815
BCA: BCE_0062(hpt) BCE_4975(hpt)
BCZ: BCZK0059(hprT) BCZK4569(hpt)
BCR: BCAH187_A0075(hpt) BCAH187_A4958(hpt2)
BCB: BCB4264_A0071(hpt) BCB4264_A4942(hpt2)
BCU: BCAH820_0072(hpt) BCAH820_4937(hpt2)
BCG: BCG9842_B0297(hpt_1) BCG9842_B5245(hpt_2)
BCQ: BCQ_0073(hprT) BCQ_4632(hpt)
BCX: BCA_0076(hpt) BCA_4958(hpt2)
BCY: Bcer98_0059 Bcer98_3479
BTK: BT9727_0059(hprT) BT9727_4551(hpt)
BTL: BALH_0062(hpt) BALH_4389(hpt)
BWE: BcerKBAB4_0059 BcerKBAB4_4651
BLI: BL05003(hprT)
BLD: BLi00084(hprT)
BCL: ABC0105(hprT)
BAY: RBAM_000790(hprT)
BPU: BPUM_0052(hprT)
OIH: OB0078
GKA: GK0061
GTN: GTNG_0061
GWC: GWCH70_0063
GYM: GYMC10_0054
GYC: GYMC61_0061
AFL: Aflv_0061(hprT)
SAU: SA0468
SAV: SAV0510
SAW: SAHV_0507
SAM: MW0465
SAR: SAR0511(hpt)
SAS: SAS0467
SAC: SACOL0554(hpt)
SAB: SAB0459(hpt)
SAA: SAUSA300_0488(hpt)
SAX: USA300HOU_0504(hpt)
SAO: SAOUHSC_00485
SAJ: SaurJH9_0532
SAH: SaurJH1_0545
SAE: NWMN_0472(hpt)
SAD: SAAV_0457(hpt)
SEP: SE2273
SER: SERP0149(hpt)
SHA: SH2501
SSP: SSP2246
SCA: Sca_0161(hpt)
LMO: lmo0219
LMF: LMOf2365_0230
LMH: LMHCC_2424
LMC: Lm4b_00217
LIN: lin0251
LWE: lwe0182
LSP: Bsph_0087
ESI: Exig_0051 Exig_0895
EAT: EAT1b_0531 EAT1b_1677
MCL: MCCL_1903
BBE: BBR47_01220(hprT)
PJD: Pjdr2_0062
AAC: Aaci_0199
LLA: L160442(hprT) L25115(hpt)
LLK: LLKF_0021(hpt) LLKF_1638(hprT)
LLC: LACR_0017 LACR_1606
LLM: llmg_0020(hpt) llmg_0993(hprT)
SPZ: M5005_Spy_0012
SPM: spyM18_0013(hpt)
SPG: SpyM3_0011(hpt)
SPS: SPs0012
SPH: MGAS10270_Spy0012
SPI: MGAS10750_Spy0012
SPJ: MGAS2096_Spy0012
SPK: MGAS9429_Spy0012
SPF: SpyM50012(hpt)
SPA: M6_Spy0012
SPB: M28_Spy0012(hpt)
SOZ: Spy49_0012(hpt)
SPN: SP_0012
SPD: SPD_0012(hpt)
SPR: spr0011(hgt)
SPW: SPCG_0011(hgt)
SPX: SPG_0012(hpt)
SNE: SPN23F_00120(hpt)
SPV: SPH_0012(hpt)
SNM: SP70585_0012(hpt)
SJJ: SPJ_0012(hpt)
SPP: SPP_0012(hpt)
SNT: SPT_0046(hpt)
SAG: SAG0015(hpt)
SAN: gbs0014
SAK: SAK_0014(hpt)
SMU: SMU.14(hprT)
STC: str0011(hpt)
STL: stu0011(hpt)
STE: STER_0013
SSA: SSA_0014(hpt)
SSU: SSU05_0014
SSV: SSU98_0017
SSB: SSUBM407_0014(hpt)
SSI: SSU0014(hpt)
SSS: SSUSC84_0014(hpt)
SGO: SGO_2134(hpt)
SEQ: SZO_00140
SEZ: Sez_0013(hpt)
SEU: SEQ_0014
SUB: SUB0014(hpt)
SDS: SDEG_0014(hpt)
LPL: lp_0546(hprT)
LPJ: JDM1_0444(hprT)
LJO: LJ0689 LJ0808
LJF: FI9785_539(hprT) FI9785_662(hpt)
LAC: LBA0613(hprT)
LSA: LSA1598(hpt)
LSL: LSL_1354(hpt)
LDB: Ldb0538(hprT)
LBU: LBUL_0480
LBR: LVIS_0522
LCA: LSEI_2541
LCB: LCABL_27080(hpt)
LGA: LGAS_0472 LGAS_0566
LRE: Lreu_0267 Lreu_1925
LRF: LAR_0256 LAR_1802
LHE: lhv_0646 lhv_1180
LFE: LAF_0220
LRH: LGG_02515(hpt)
LRL: LC705_02519(hpt)
PPE: PEPE_1546
EFA: EF0264(hpt)
OOE: OEOE_0187 OEOE_1124
LME: LEUM_0403 LEUM_1389
LCI: LCK_00619(hpt1) LCK_01423(hpt2)
CAC: CAC3203(hprT)
CPE: CPE1960(hprT) CPE2471(hprT)
CPF: CPF_2216(hpt) CPF_2787(hpt)
CPR: CPR_1928(hpt) CPR_2473(hpt)
CTC: CTC00203 CTC02240
CNO: NT01CX_1039 NT01CX_1811
CTH: Cthe_2254
CDF: CD2691(hpt) CD3231(hpt)
CDC: CD196_2532(hpt) CD196_3045(hpt)
CDL: CDR20291_2579(hpt) CDR20291_3091(hpt)
CBO: CBO3081(hpt) CBO3525(hpt)
CBA: CLB_3110(hpt-1) CLB_3600(hpt-2)
CBH: CLC_2983(hpt-1) CLC_3489(hpt-2)
CBY: CLM_3486(hpt) CLM_4011(hpt)
CBL: CLK_2474(hpt) CLK_2990(hpt)
CBK: CLL_A0171(hpt) CLL_A1003(hpt)
CBB: CLD_0965(hpt) CLD_1459(hpt)
CBI: CLJ_B3346(hpt_1) CLJ_B3849(hpt_2)
CBT: CLH_0164(hpt) CLH_0938(hpt)
CBF: CLI_3140(hpt-1) CLI_3734(hpt-2)
CBE: Cbei_0099 Cbei_4228
CKL: CKL_0171(hpt)
CKR: CKR_0140
CPY: Cphy_0140
CCE: Ccel_0084
AMT: Amet_1621 Amet_2903
AOE: Clos_1353 Clos_2015
STH: STH500
SWO: Swol_1785
VPR: Vpar_0503
ATE: Athe_0641
DSY: DSY3939
DHD: Dhaf_1437
DRM: Dred_2376
DAE: Dtox_0723
PTH: PTH_2552(hpt)
DAU: Daud_1636
HMO: HM1_0058(hpt)
FMA: FMG_0806 FMG_0995
APR: Apre_0623
EEL: EUBELI_01869
ERE: EUBREC_0534
TTE: TTE2394(hpt)
TEX: Teth514_0792
TPD: Teth39_0300
CHY: CHY_1067(hpt)
MTA: Moth_2106
ADG: Adeg_0886
CSC: Csac_1209
CPO: COPRO5265_0916(hpt)
NTH: Nther_0080
HOR: Hore_00570
MGE: MG_458(hpt)
MPN: MPN672(hpt)
MPU: MYPU_5510(hpt)
MPE: MYPE10260(hpt) MYPE5810(htp)
MGA: MGA_0658(hpt)
MMY: MSC_0256(hpt) MSC_0848(hpt)
MMO: MMOB4340(hpt)
MHY: mhp117(hpt)
MHJ: MHJ_0254(hpt)
MHP: MHP7448_0262(hpt)
MSY: MS53_0381(hpt)
MCP: MCAP_0216(hpt1) MCAP_0765(hpt2)
MAA: MAG_3840(hpt)
MAT: MARTH_orf377(hpt)
MHO: MHO_1940(hpt)
UUR: UU104(hpt)
UPA: UPA3_0107(hpt)
UUE: UUR10_0112(hpt)
ACL: ACL_1385(hpt)
MFL: Mfl463
MTU: Rv3624c(hpt)
MTC: MT3726(hpt)
MRA: MRA_3660(hpt)
MTF: TBFG_13655
MTB: TBMG_03661(TBMG_03661.1)
MBO: Mb3648c(hpt)
MBB: BCG_3682c(hpt)
MBT: JTY_3683(hpt)
MLE: ML0214(hpt)
MLB: MLBr_00214(hpt)
MPA: MAP0439(hpt)
MAV: MAV_0532(hpt)
MSM: MSMEG_6110(hpt)
MUL: MUL_4200(hpt)
MVA: Mvan_5377
MGI: Mflv_1412
MAB: MAB_0523
MMC: Mmcs_4775
MKM: Mkms_4861
MJL: Mjls_5161
MMI: MMAR_5124(hpt)
CGL: NCgl2604(cgl2697)
CGB: cg2985(hpt)
CGT: cgR_2598
CEF: CE2543
CDI: DIP2003(hpt)
CJK: jk0277(hpt)
CUR: cur_1703
CAR: cauri_2245(hpt)
CKP: ckrop_1652(hpt)
NFA: nfa3890(hpt)
RHA: RHA1_ro04404(hpt)
RER: RER_06210(hpt)
ROP: ROP_43200(hpt)
GBR: Gbro_4019
SCO: SCO3405(hprT)
SMA: SAV_4665(hprT)
SGR: SGR_4087
TWH: TWT589(hpt)
TWS: TW172(hpt)
LXX: Lxx21510(hpt)
CMI: CMM_0843(hptA)
CMS: CMS_0098
ART: Arth_0150
AAU: AAur_0134(hpt)
ACH: Achl_0311
RSA: RSal33209_3219
KRH: KRH_19290(hpt)
MLU: Mlut_01220
BCV: Bcav_0701
BFA: Bfae_12790
JDE: Jden_2105
KSE: Ksed_24790
XCE: Xcel_2988
PAC: PPA0259
NCA: Noca_0443
TFU: Tfu_2896
TCU: Tcur_4506
SRO: Sros_9176
FRA: Francci3_4313
FRE: Franean1_0299
FAL: FRAAL6587(hpt)
ACE: Acel_0203
NML: Namu_0847
KRA: Krad_0530
SEN: SACE_0395(hpt)
SVI: Svir_35700
AMI: Amir_0311
STP: Strop_4309
SAQ: Sare_4745
CAI: Caci_8427
BLO: BL1681(hprT)
BLJ: BLD_1847(hpt)
BLN: Blon_0548
BAD: BAD_0408(hprT)
BLA: BLA_0473(hpt)
BLC: Balac_0498
BLT: Balat_0498
RXY: Rxyl_2186 Rxyl_2835
AFO: Afer_1913
CCU: Ccur_02170
SHI: Shel_02020
APV: Apar_0107
ELE: Elen_2897
BTU: BT0421A
BHR: BH0421A
BDU: BDU_418(hpt)
BRE: BRE_422(hpt)
LIL: LA4295
LIC: LIC13438(hpt)
LBJ: LBJ_2933(hpt)
LBL: LBL_0130(hpt)
LBI: LEPBI_I3157(hpt)
LBF: LBF_3048(hpt)
BHY: BHWA1_01908(hpt)
ABA: Acid345_3058
ACA: ACP_0161(hpt)
SUS: Acid_0128 Acid_5665
BTH: BT_4386
BFR: BF1119
BFS: BF1031
BVU: BVU_1681
PGI: PG0792(hpt)
PGN: PGN_0815
PDI: BDI_1899
APS: CFPG_467
SRU: SRU_1710(hpt)
RMR: Rmar_0965
DFE: Dfer_3743
CPI: Cpin_6908
PHE: Phep_0044
FJO: Fjoh_0421
FPS: FP1360(hpt)
FBA: FIC_00746
FSU: Fisuc_0732
FNU: FN0288
LBA: Lebu_1306
STR: Sterm_2046 Sterm_2148
SMF: Smon_0329 Smon_0512
OTE: Oter_3617
MIN: Minf_1659(hpt)
AMU: Amuc_1937
GAU: GAU_1392(hpt)
RBA: RB6524(hpt)
EMI: Emin_1323
TAI: Taci_0847
GVI: glr2790
CTE: CT1527(gpt)
CPC: Cpar_1613
CPH: Cpha266_1917
CPB: Cphamn1_1746
PLT: Plut_1525
PAA: Paes_1623
CTS: Ctha_1467
DET: DET0749(hpt-1) DET0792(hpt-2)
DEH: cbdb_A722(hpt) cbdb_A770(hpt)
DEB: DehaBAV1_0677 DehaBAV1_0718
DEV: DhcVS_655(hpt1) DhcVS_698(hpt2)
RRS: RoseRS_0321
RCA: Rcas_0865
CAU: Caur_2039
CAG: Cagg_2663
CHL: Chy400_2199
HAU: Haur_3028
TRO: trd_0295 trd_A0384
STI: Sthe_0776
DRA: DR_1376
DGE: Dgeo_1588
DDR: Deide_14150
TTH: TTC1766
TTJ: TTHA0220
AAE: aq_544(hpt)
HYA: HY04AAS1_0249
SUL: SYO3AOP1_1764
SAF: SULAZ_0715(hpt)
PMX: PERMA_1567(hpt)
TMA: TM0206
TPT: Tpet_0718
TLE: Tlet_0012
TRQ: TRQ2_0742
TNA: CTN_0479
TNP: Tnap_0836
TME: Tmel_1560
TAF: THA_1893
FNO: Fnod_1773
PMO: Pmob_1370
KOL: Kole_0004
DTH: DICTH_1898(hpt)
DTU: Dtur_0169
TYE: THEYE_A0570(hpt)
TTR: Tter_0033
Taxonomy
Structures PDB: 1BZY  1CJB  1D6N  1DQN  1DQP  1FSG  1G9S  1G9T  1GRV  1HGX  
     1HMP  1I0I  1I0L  1I13  1I14  1J7J  1P17  1P18  1P19  1PZM  
     1QK3  1QK4  1QK5  1R3U  1TC1  1TC2  1YFZ  1Z7G  2GEB  2JBH  
     2JKY  2JKZ  2VFA  2YWS  2YWT  2YWU  3GEP  3GGC  3GGJ  3KB8  
Reference
  Authors
  Title
  Journal
 1
Flaks, J.G.
Nucleotide synthesis from 5-phosphoribosylpyrophosphate.
Methods Enzymol. 6 (1963) 136-158.
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:14392175]
KORNBERG A, LIEBERMAN I, SIMMS ES.
Enzymatic synthesis of purine nucleotides.
J. Biol. Chem. 215 (1955) 417-27.
Saccharomyces cerevisiae　[GN:sce]
Reference
  Authors
  Title
  Journal
  Organism
 3  [PMID:13436452]
LUKENS LN, HERRINGTON KA.
Enzymic formation of 6-mercaptopurine tibo tide.
Biochim. Biophys. Acta. 24 (1957) 432-3.
Bos taurus [GN:bta]
Reference
  Authors
  Title

  Journal
  Organism
 4  [PMID:13271449]
REMY CN, REMY WT, BUCHANAN JM.
Biosynthesis of the purines.  VIII.  Enzymatic synthesis and
utilization of alpha-5-phosphoribosylpyrophosphate.
J. Biol. Chem. 217 (1955) 885-95.
Bos taurus [GN:bta]
Other DBs ExplorEnz - The Enzyme Database: 2.4.2.8
IUBMB Enzyme Nomenclature: 2.4.2.8
ExPASy - ENZYME nomenclature database: 2.4.2.8
BRENDA, the Enzyme Database: 2.4.2.8
CAS: 9016-12-0
DBGET integrated database retrieval system