| Entry |
|
|---|
| Name |
galactosyldiacylglycerol alpha-2,3-sialyltransferase |
|---|
| Class |
Transferases;
Glycosyltransferases;
Transferring other glycosyl groups
 |
|---|
| Sysname |
CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol
N-acetylneuraminyltransferase |
|---|
| Reaction(IUBMB) |
CMP-N-acetylneuraminate + 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol
= CMP +
1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-
glycerol [RN:R03468] |
|---|
| Reaction(KEGG) |
R03468
 |
|---|
| Substrate |
CMP-N-acetylneuraminate [CPD:C00128];
1,2-diacyl-3-beta-D-galactosyl-sn-glycerol [CPD:C03692] |
|---|
| Product |
CMP [CPD:C00055];
1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-
glycerol [CPD:C04872] |
|---|
| Comment |
The beta-D-galactosyl residue of the oligosaccharide of
glycoproteins may also act as acceptor. |
|---|
| Pathway |
PATH: ec00561 Glycerolipid metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:7298658]
Pieringer J, Keech S, Pieringer RA.
Biosynthesis in vitro of sialosylgalactosyldiacylglycerol by mouse
brain microsomes.
J. Biol. Chem. 256 (1981) 12306-9.
Mus musculus [GN:mmu] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:7142179]
Weinstein J, de Souza-e-Silva U, Paulson JC.
Purification of a Gal beta 1 to 4GlcNAc alpha 2 to 6
sialyltransferase and a Gal beta 1 to 3(4)GlcNAc alpha 2 to 3
sialyltransferase to homogeneity from rat liver.
J. Biol. Chem. 257 (1982) 13835-44.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:7142180]
Weinstein J, de Souza-e-Silva U, Paulson JC.
Sialylation of glycoprotein oligosaccharides N-linked to asparagine.
Enzymatic characterization of a Gal beta 1 to 3(4)GlcNAc alpha 2 to
3 sialyltransferase and a Gal beta 1 to 4GlcNAc alpha 2 to 6
sialyltransferase from rat liver.
J. Biol. Chem. 257 (1982) 13845-53.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.4.99.5
IUBMB Enzyme Nomenclature: 2.4.99.5
ExPASy - ENZYME nomenclature database: 2.4.99.5
BRENDA, the Enzyme Database: 2.4.99.5
CAS: 80237-98-5 |
|---|
