| Entry |
|
|---|
| Name |
alkylglycerone-phosphate synthase;
alkyldihydroxyacetonephosphate synthase;
alkyldihydroxyacetone phosphate synthetase;
alkyl DHAP synthetase;
alkyl-DHAP;
dihydroxyacetone-phosphate acyltransferase;
DHAP-AT |
|---|
| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only
sub-subclass identified to date)
 |
|---|
| Sysname |
1-acyl-glycerone-3-phosphate:long-chain-alcohol
O-3-phospho-2-oxopropanyltransferase |
|---|
| Reaction(IUBMB) |
1-acyl-glycerone 3-phosphate + a long-chain alcohol = an
alkyl-glycerone 3-phosphate + a long-chain acid anion [RN:R04311] |
|---|
| Reaction(KEGG) |
R04311
 |
|---|
| Substrate |
1-acyl-glycerone 3-phosphate [CPD:C03372];
long-chain alcohol [CPD:C00339] |
|---|
| Product |
alkyl-glycerone 3-phosphate [CPD:C03715];
long-chain acid anion [CPD:C03129] |
|---|
| Comment |
The ester-linked fatty acid of the substrate is cleaved and replaced
by a long-chain alcohol in an ether linkage. |
|---|
| Pathway |
PATH: ec00565 Ether lipid metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00803 alkyldihydroxyacetonephosphate synthase |
|---|
| Genes |
HSA: 8540(AGPS)
PTR: 740316(AGPS)
MMU: 228061(Agps)
RNO: 84114(Agps)
CFA: 488421(AGPS)
BTA: 613679(AGPS)
MDO: 100019424
OAA: 100084919
GGA: 424135(AGPS)
TGU: 100220704
XLA: 446408(agps)
XTR: 100145360
DRE: 386801(agps)
BFO: BRAFLDRAFT_213219
SPU: 585499
DME: Dmel_CG10253
DPO: Dpse_GA24243
DAN: Dana_GF12633
DER: Dere_GG22382
DPE: Dper_GL11706
DSE: Dsec_GM20165
DSI: Dsim_GD25643
DYA: Dyak_GE12271
DGR: Dgri_GH20803
DMO: Dmoj_GI20890
AGA: AgaP_AGAP004358
AAG: AaeL_AAEL007789
CQU: CpipJ_CPIJ008026
NVI: 100115142
API: 100168099
ISC: IscW_ISCW016253
CEL: Y50D7A.7(ads-1)
CBR: CBG15716
BMY: Bm1_07035
NVE: NEMVE_v1g240794
HMG: 100197532
TAD: TRIADDRAFT_31058
DDI: DDB_0191146(agps)
TET: TTHERM_00053800
PTM: GSPATT00008502001 GSPATT00027743001
TBR: Tb927.6.1500
TCR: 503815.10 505807.110
LMA: LmjF30.0120
LIF: LinJ30.0120
LBZ: LbrM30_V2.0130
PTI: PHATR_44190
TPS: THAPSDRAFT_33895
SPE: Spro_2461
PAE: PA3026
PAU: PA14_24940
PAP: PSPA7_2132
PAG: PLES_20341
PFL: PFL_2767
PMY: Pmen_1558
PCR: Pcryo_0015
SSE: Ssed_0594
SHL: Shal_3330
SWD: Swoo_4359
MAQ: Maqu_1346
CBS: COXBURSA331_A2176
CBG: CbuG_0296
CBC: CbuK_0216
HCH: HCH_04625
ABO: ABO_1409
REH: H16_B1197
RME: Rmet_5443
BUR: Bcep18194_B2080
BCJ: BCAM1106
BMU: Bmul_4576
BMJ: BMULJ_03934(agpS)
BPY: Bphyt_6436
RFR: Rfer_2332
POL: Bpro_5107
VEI: Veis_1876
DAC: Daci_1119
DOL: Dole_2614
DAL: Dalk_3178
MXA: MXAN_1676
SCL: sce9031 sce9321
HOH: Hoch_3321
PLA: Plav_1669
OAN: Oant_2462
RPA: RPA1261
RPB: RPB_1270
RPD: RPD_1036 RPD_3848
RPT: Rpal_1454
OCA: OCAR_5302
MNO: Mnod_8219
CPY: Cphy_3390
MTU: Rv2250A Rv2251 Rv3107c(agpS)
MTC: MT2311 MT3190
MRA: MRA_2271 MRA_3139(agpS)
MTF: TBFG_12280 TBFG_13124
MTB: TBMG_00859(TBMG_00859.1) TBMG_01729(TBMG_01729.1)
MBO: Mb2275 Mb3134c(agpS)
MBB: BCG_2269 BCG_3132c(agpS)
MBT: JTY_2263 JTY_3127(agpS)
MPA: MAP2004
MAV: MAV_2186
MSM: MSMEG_4334
MUL: MUL_1298
MVA: Mvan_3761
MGI: Mflv_2772
MAB: MAB_3884
MMC: Mmcs_3374
MKM: Mkms_3436
MJL: Mjls_3385
MMI: MMAR_1525(agpS) MMAR_3344
NFA: nfa13450
RHA: RHA1_ro05090
RER: RER_50150
ROP: ROP_51520
GBR: Gbro_4399
SCO: SCO0668(SCF91.28c)
KRH: KRH_18610
BFA: Bfae_27110
NCA: Noca_4590
TCU: Tcur_1798
SRO: Sros_4360 Sros_6682
FRA: Francci3_0943
FRE: Franean1_5599
FAL: FRAAL1575
KRA: Krad_1001
SEN: SACE_0660 SACE_3960
SVI: Svir_33270
STP: Strop_2577 Strop_3120
SAQ: Sare_2774 Sare_3350
TDE: TDE0138
LIL: LA2262(adaS)
LIC: LIC11674
LBI: LEPBI_II0038(eapA)
LBF: LBF_4037
HAU: Haur_0358
TLE: Tlet_1460
TTR: Tter_2454
AFU: AF0868
TGA: TGAM_1021
TSI: TSIB_0773
APE: APE_0308.1(eapA)
SSO: SSO1531
SAI: Saci_1188
SIM: M1627_0891
TPE: Tpen_1372
KCR: Kcr_0300
 |
|---|
| Structures |
PDB: 2UUU 2UUV |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:7096336]
Brown AJ, Snyder F.
Alkyldihydroxyacetone-P synthase. Solubilization, partial
purification, new assay method, and evidence for a ping-pong
mechanism.
J. Biol. Chem. 257 (1982) 8835-9.
Mus musculus [GN:mmu] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:4401994]
Wykle RL, Plantadosi C, Snyder F.
The role of acyldihydroxyacetone phosphate, reduced nicotinamide
adenine dinucleotide, and reduced nicotinamide adenine dinucleotide
phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal
enzymes of Ehrlich ascites tumor.
J. Biol. Chem. 247 (1972) 2944-8.
Mus musculus [GN:mmu], Cavia porcellus, Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.5.1.26
IUBMB Enzyme Nomenclature: 2.5.1.26
ExPASy - ENZYME nomenclature database: 2.5.1.26
BRENDA, the Enzyme Database: 2.5.1.26
CAS: 64060-42-0 102484-74-2 |
|---|
