| Entry |
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| Name |
alkylglycerone-phosphate synthase;
alkyldihydroxyacetonephosphate synthase;
alkyldihydroxyacetone phosphate synthetase;
alkyl DHAP synthetase;
alkyl-DHAP;
dihydroxyacetone-phosphate acyltransferase;
DHAP-AT
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| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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| Sysname |
1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase
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| Reaction(IUBMB) |
1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion [RN: R04311]
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| Reaction(KEGG) |
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| Substrate |
1-acyl-glycerone 3-phosphate [CPD: C03372];
long-chain alcohol [CPD: C00339]
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| Product |
alkyl-glycerone 3-phosphate [CPD: C03715];
long-chain acid anion [CPD: C03129]
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| Comment |
The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.
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| Pathway |
| Ether lipid metabolism | | Metabolic pathways |
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| Orthology |
| alkyldihydroxyacetonephosphate synthase |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | SPU: | | DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DSI: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | AGA: | | AAG: | | CQU: | | AME: | | NVI: | | API: | | PHU: | | ISC: | | CEL: | | CBR: | | BMY: | | NVE: | | HMG: | | TAD: | | AQU: | | NGR: | | DDI: | | DPP: | | TET: | | PTM: | | TBR: | | TCR: | | LMA: | | LIF: | | LDO: | | LMI: | | LBZ: | | PTI: | | TPS: | | PIF: | | SPE: | | RHD: | | PAE: | | PAU: | | PAP: | | PAG: | | PAF: | | PNC: | | PDK: | | PPUU: | | PFL: | | PMY: | | PMK: | | PDR: | | PCR: | | SSE: | | SHL: | | SWD: | | MAQ: | | MHC: | | MAD: | | MBS: | | FBL: | | CBS: | | CBG: | | CBC: | | HCH: | | ABO: | | ADI: | | GPB: | | REH: | | RME: | | CNC: | | BUR: | | BCJ: | | BMU: | | BMJ: | | BPY: | | BRH: | | RFR: | | POL: | | VEI: | | DAC: | | DEL: | | DOL: | | DAL: | | MXA: | | MFU: | | MSD: | | SCL: | | HOH: | | DBR: | | PLA: | | OAN: | | RPA: | | RPB: | | RPD: | | RPT: | | RPX: | | OCA: | | OCG: | | OCO: | | MNO: | | PSF: | | CPY: | | DOR: | | ELM: | | TMR: | | MTU: | | MTV: | | MTC: | | MRA: | | MTF: | | MTB: | | MTK: | | MTZ: | | MTG: | | MTI: | | MTE: | | MTL: | | MTO: | | MTD: | | MTN: | | MTJ: | | MTUB: | | MBO: | | MBB: | | MBT: | | MBM: | | MBK: | | MAF: | | MCE: | | MCQ: | | MCV: | | MCX: | | MCZ: | | MPA: | | MAV: | | MIT: | | MIR: | | MIA: | | MID: | | MSM: | | MSG: | | MSA: | | MUL: | | MVA: | | MGI: | | MSP: | | MAB: | | MMV: | | MMC: | | MKM: | | MJL: | | MJD: | | MMI: | | MRH: | | MMM: | | MCB: | | MLI: | | ASD: | | CRD: | | CVA: | | NFA: | | NCY: | | NBR: | | RHA: | | RER: | | ROP: | | REQ: | | GBR: | | GOR: | | TPR: | | SCO: | | SHY: | | SHO: | | SVE: | | SDV: | | SALB: | | KRH: | | BFA: | | SKE: | | ICA: | | PFR: | | PPC: | | MPH: | | NCA: | | KFL: | | NDA: | | NAL: | | TCU: | | SRO: | | FRA: | | FRE: | | FRI: | | FAL: | | FSY: | | BSD: | | MMAR: | | KRA: | | SEN: | | SVI: | | TBI: | | AMD: | | AMN: | | AMM: | | PDX: | | SESP: | | STP: | | SAQ: | | ASE: | | MCU: | | CWO: | | TDE: | | LIL: | | LIE: | | LIC: | | LBI: | | LBF: | | TPX: | | HAU: | | DMR: | | TLE: | | TTA: | | TTR: | | AFU: | | TGA: | | TSI: | | THE: | | APE: | | SSO: | | SOL: | | SAI: | | SACN: | | SACR: | | SIM: | | POG: | | VDI: | | VMO: | | TPE: | | KCR: | |
» show all
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| Reference |
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| Authors |
Brown AJ, Snyder F. |
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| Title |
Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism. |
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| Journal |
J. Biol. Chem. 257 (1982) 8835-9. |
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| Organism |
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| Reference |
|
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| Authors |
Wykle RL, Plantadosi C, Snyder F. |
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| Title |
The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor. |
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| Journal |
J. Biol. Chem. 247 (1972) 2944-8. |
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| Organism |
Mus musculus [GN: mmu], Cavia porcellus, Rattus norvegicus [GN: rno] |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 64060-42-0 102484-74-2 |
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