KEGG   ENZYME: 2.5.1.30Help
Entry
EC 2.5.1.30                 Enzyme                                 
Name trans-hexaprenyltranstransferase;
all-trans-heptaprenyl-diphosphate synthase;
heptaprenyl pyrophosphate synthase;
heptaprenyl diphosphate synthase;
heptaprenyl pyrophosphate synthetase;
HepPP synthase
Class Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only
sub-subclass identified to date)
BRITE hierarchy
Sysname all-trans-hexaprenyl-diphosphate:isopentenyl-diphosphate
hexaprenyltranstransferase
Reaction(IUBMB) all-trans-hexaprenyl diphosphate + isopentenyl diphosphate =
diphosphate + all-trans-heptaprenyl diphosphate [RN:R05612]
Reaction(KEGG) R05612
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Substrate all-trans-hexaprenyl diphosphate [CPD:C01230];
isopentenyl diphosphate [CPD:C00129]
Product diphosphate [CPD:C00013];
all-trans-heptaprenyl diphosphate [CPD:C04216]
Comment This enzyme will also use trans-trans-farnesyl diphosphate and
all-trans-prenyl diphosphates of intermediate size as donors, but
not dimethylallyl diphosphate.
Pathway PATH: ec00900  Terpenoid backbone biosynthesis
Orthology KO: K00805  trans-hexaprenyltranstransferase
Genes PCR: Pcryo_1756
SFR: Sfri_3090
SAZ: Sama_2830
SBL: Sbal_0966
SLO: Shew_0868
SPC: Sputcn32_0978
SHE: Shewmr4_0894
SHM: Shewmr7_3126
SHW: Sputw3181_3189
PAT: Patl_3739
SDE: Sde_1007
PIN: Ping_0524
AEH: Mlg_0833
HHA: Hhal_1849
CSA: Csal_0473
REH: H16_A3253(grcC)
BCH: Bcen2424_0580
BAM: Bamb_0483
POL: Bpro_0840
PNA: Pnap_0752
AAV: Aave_3676
AZO: azo0401
MFA: Mfla_2220
SFU: Sfum_1586
JAN: Jann_0487
PDE: Pden_2031
MMR: Mmar10_2184
MGM: Mmc1_3354
BSU: BSU22740(hepT) BSU22760(hepS)
BHA: BH1648(gerCA) BH1653(gerCC)
BAN: BA1533 BA1535(hepT)
BAR: GBAA1533 GBAA1535(hepT)
BAA: BA_2053 BA_2055
BAT: BAS1422 BAS1424
BAH: BAMEG_3058(hepT)
BAI: BAA_1602 BAA_1604(hepT)
BCE: BC1512 BC1514
BCA: BCE_1639 BCE_1641(hepT)
BCZ: BCZK1394(hepS) BCZK1396(hepT)
BCR: BCAH187_A1677(hepT)
BCB: BCB4264_A1568 BCB4264_A1570(hepT)
BCU: BCAH820_1608(hepT)
BCG: BCG9842_B3775(hepT)
BCQ: BCQ_1583(hepT)
BCX: BCA_1573(hepT)
BCY: Bcer98_1235 Bcer98_1237
BTK: BT9727_1394(hepS) BT9727_1396(hepT)
BTL: BALH_1366 BALH_1368(hepT)
BWE: BcerKBAB4_1436 BcerKBAB4_1438
BLI: BL02782(hepT) BL02784(hepS)
BLD: BLi02409(hepT) BLi02411(hepS)
BCL: ABC1885 ABC1889(hepA)
BAY: RBAM_020900(hepT) RBAM_020920(hepS)
BPU: BPUM_2005(hepT) BPUM_2007(hepS)
OIH: OB1788(gerCC) OB1790(gerCA)
GKA: GK2210(gerCC) GK2212(gerCA)
GTN: GTNG_2144 GTNG_2146
GWC: GWCH70_2149 GWCH70_2151
AFL: Aflv_1095(hepT)
SAU: SA1302(gerCC)
SAV: SAV1470(gerCC)
SAM: MW1359(gerCC)
SAR: SAR1479
SAS: SAS1411
SAC: SACOL1510
SAB: SAB1332c
SAA: SAUSA300_1359
SAO: SAOUHSC_01486
SAJ: SaurJH9_1527
SAH: SaurJH1_1557
SAE: NWMN_1379(hepT)
SEP: SE1157
SER: SERP1038
SHA: SH1444(gerCC)
SSP: SSP1276
LMO: lmo1930
LMF: LMOf2365_1959(hepB)
LIN: lin2044
LWE: lwe1956(hepB) lwe1958(hepS) lwe2591
LSP: Bsph_1934
ESI: Exig_1798
EAT: EAT1b_2995
LLC: LACR_0190
LLM: llmg_0196 llmg_1110(ispB) llmg_1111(gerCA)
LPL: lp_1066(hepB1) lp_1134(hepB2)
LSL: LSL_1028
LCA: LSEI_2300
LRE: Lreu_1084
CTC: CTC01025
CTH: Cthe_0564
STH: STH190
SWO: Swol_0680
DSY: DSY2232
DRM: Dred_2166
PTH: PTH_0969(ispA)
DAU: Daud_1350
EEL: EUBELI_00292
CHY: CHY_1206(hepT)
MTA: Moth_1252
MTU: Rv0562(grcC1) Rv0989c(grcC2)
MTC: MT0588 MT1018
MRA: MRA_0569(grcC1) MRA_0996(grcC2)
MBO: Mb0577(grcC1) Mb1016c(grcC2)
MBB: BCG_0607(grcC1) BCG_1044c(grcC2)
MLE: ML2277
MPA: MAP4058(grcC1)
MAV: MAV_4581
MUL: MUL_0664(grcC1)
MVA: Mvan_0992
MGI: Mflv_5253
MAB: MAB_3928c
MMC: Mmcs_0771
MKM: Mkms_0785
MJL: Mjls_0766
CGL: NCgl0456(cgl0473)
CGB: cg0559(ispB) cg2384(idsA)
CGT: cgR_0576
CEF: CE0483
CDI: DIP0429
CJK: jk1863
NFA: nfa51220
RHA: RHA1_ro01991
SCO: SCO4583(SCD20.01)
SMA: SAV_4864(grcC)
SGR: SGR_2964
TWH: TWT054(grcC)
TWS: TW064
LXX: Lxx01830(hepB)
CMI: CMM_2807(menX)
ART: Arth_3130
AAU: AAur_3100
RSA: RSal33209_2635
KRH: KRH_05440
PAC: PPA1921
NCA: Noca_0534
TFU: Tfu_2681
FRA: Francci3_0552
FRE: Franean1_6080
FAL: FRAAL1046
ACE: Acel_0281
KRA: Krad_0649
SEN: SACE_6888
STP: Strop_4051
SAQ: Sare_4449
RXY: Rxyl_1972
ABA: Acid345_2027
FNU: FN1541
SYD: Syncc9605_1137
SYE: Syncc9902_1320
PMN: PMN2A_0055
PMI: PMT9312_0618
PMB: A9601_06741(sds)
PMC: P9515_06831(sds)
PMG: P9301_06441(sds)
PME: NATL1_06761(sds)
TER: Tery_0157
RRS: RoseRS_0139
Taxonomy
Structures PDB: 2E8T  2E8U  2E8V  2E8W  2E8X  2E90  2E91  2E92  2E93  2E94  
     2E95  2Z4V  2Z4W  2Z4X  2Z4Y  2Z4Z  2Z50  2Z52  2Z78  2Z7H  
     2Z7I  2ZEU  2ZEV  
Reference
  Authors
  Title
  Journal
  Organism
 1  [PMID:6768722]
Takahashi I, Ogura K, Seto S.
Heptaprenyl pyrophosphate synthetase from Bacillus subtilis.
J. Biol. Chem. 255 (1980) 4539-43.
Bacillus subtilis [GN:bsu]
Other DBs ExplorEnz - The Enzyme Database: 2.5.1.30
IUBMB Enzyme Nomenclature: 2.5.1.30
ExPASy - ENZYME nomenclature database: 2.5.1.30
BRENDA, the Enzyme Database: 2.5.1.30
CAS: 74506-59-5
DBGET integrated database retrieval system