dme:7292047 : No such data.

KEGG   ENZYME: 2.5.1.56Help
Entry
EC 2.5.1.56                 Enzyme                                 
Name N-acetylneuraminate synthase;
(NANA)condensing enzyme;
N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating);
NeuAc synthase
Class Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only
sub-subclass identified to date)
BRITE hierarchy
Sysname phosphoenolpyruvate:N-acetyl-D-mannosamine
C-(1-carboxyvinyl)transferase (phosphate-hydrolysing,
2-carboxy-2-oxoethyl-forming)
Reaction(IUBMB) phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate +
N-acetylneuraminate [RN:R01804]
Reaction(KEGG) R01804;
(other) R04435
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Substrate phosphoenolpyruvate [CPD:C00074];
N-acetyl-D-mannosamine [CPD:C00645];
H2O [CPD:C00001]
Product phosphate [CPD:C00009];
N-acetylneuraminate [CPD:C00270]
Pathway PATH: ec00520  Amino sugar and nucleotide sugar metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K01654  N-acetylneuraminate synthase
KO: K05304  sialic acid synthase
Genes HSA: 54187(NANS)
PTR: 743934(NANS)
MCC: 715459
MMU: 94181(Nans)
RNO: 298071(Nans)
CFA: 481624(NANS)
BTA: 540602(NANS)
SSC: 100155883(NANS)
ECB: 100064126(NANS)
MDO: 100014569
OAA: 100074951
GGA: 427283(NANS)
TGU: 100227675
XLA: 432051 447417
DRE: 322780
BFO: BRAFLDRAFT_115797
SPU: 577884
DME: Dmel_CG5232(Sas)
DPO: Dpse_GA18754
DAN: Dana_GF17956
AGA: AgaP_AGAP004460
AAG: AaeL_AAEL000097
CQU: CpipJ_CPIJ013964
ECI: UTI89_C3372(neuB)
ECV: APECO1_3471(neuB)
ECM: EcSMS35_3232(neuB)
ECK: EC55989_2295
ECT: ECIAI39_3443(neuB)
ECZ: ECS88_3330(neuB)
PWA: Pecwa_3027
EIC: NT01EI_1316
ETR: ETAE_1207(neuB)
VVU: VV1_0808
VVY: VV0312
VPA: VP0200
VHA: VIBHAR_00670
VEX: VEA_001800
VFI: VF_0143(neuB)
VFM: VFMJ11_0175(pseI)
VSA: VSAL_I0169 VSAL_I3011(neuB)
PPR: PBPRA2707
PPF: Pput_1483
PPW: PputW619_3707
PFL: PFL_1625
PFO: Pfl01_1523
PSA: PST_3835
PAR: Psyc_0660 Psyc_0662
ABM: ABSDF0070
ABC: ACICU_00080
SDN: Sden_1289 Sden_3113
SAZ: Sama_2331
SBL: Sbal_2958
SBM: Shew185_2977
SBN: Sbal195_3121
SBP: Sbal223_1405
SLO: Shew_1329
SPC: Sputcn32_2625
SSE: Ssed_3100
SPL: Spea_0049
SHM: Shewmr7_1391
SHN: Shewana3_1304
SHW: Sputw3181_1382
SHL: Shal_1403
SWD: Swoo_1582
ILO: IL0519(siaC) IL0551
CPS: CPS_2097
PAT: Patl_3076
AMC: MADE_02907
TTU: TERTU_1310
LPN: lpg0752(neuB)
LPF: lpl0789(neuB)
LPP: lpp0818(neuB)
LPC: LPC_2540(neuB)
FPH: Fphi_1167
TCX: Tcr_1458
AEH: Mlg_2327 Mlg_2369
HNA: Hneap_0631
HCH: HCH_04835 HCH_05266(neuB)
MMW: Mmwyl1_3564
AHA: AHA_4180(nueB)
ASA: ASA_0148(neuB)
NME: NMB0068(siaC)
NMC: NMC0052(siaC)
NMN: NMCC_0076(siaC)
CVI: CV_4031(neuB)
RPF: Rpic12D_0587
BPH: Bphy_3008
PNE: Pnec_0333
BPT: Bpet2307(neuB)
VEI: Veis_4853
HAR: HEAR1126
NEU: NE1570
NET: Neut_1549
NMU: Nmul_A0408
DAR: Daro_1248
MEI: Msip34_0133
HPY: HP0178
HPA: HPAG1_0175
HPS: HPSH_00900
HPG: HPG27_163
HPP: HPP12_0178
HPB: HELPY_0182(neuB)
HAC: Hac_0364 Hac_1271(neuB)
TDN: Suden_0595
CJE: Cj1141(neuB1) Cj1317(pseI) Cj1327(neuB2)
CJR: CJE1512(neuB) CJE1516(ptmC)
CJJ: CJJ81176_1158 CJJ81176_1334(neuB)
CJU: C8J_1251(neuB) C8J_1339
CJD: JJD26997_0385(ptmC) JJD26997_0397
CCV: CCV52592_0565
CCO: CCC13826_2303
CLA: Cla_0169(pseI) Cla_1235(ptmC)
ABU: Abu_2246(neuB)
SDL: Sdel_2213
NAM: NAMH_1595
GSU: GSU1970
GME: Gmet_0455
GUR: Gura_4086
GLO: Glov_3405
GBM: Gbem_3726
PCA: Pcar_1277
DVU: DVU0349
DVL: Dvul_0364 Dvul_2590 Dvul_2635
DVM: DvMF_1832 DvMF_1845 DvMF_1894
DDE: Dde_0423 Dde_3256 Dde_3681
DDS: Ddes_1890
DMA: DMR_13530 DMR_24590 DMR_40440
DSA: Desal_0566 Desal_3634
DBA: Dbac_0367
DRT: Dret_0614
BBA: Bd1683(neuB)
DAL: Dalk_0632 Dalk_1661
DAT: HRM2_36740(neuB)
HOH: Hoch_0346
REC: RHECIAT_CH0000837
RLT: Rleg2_0412
RHI: NGR_b09490(rkpQ)
BJA: blr5971 blr5992
RPB: RPB_1534
RPE: RPE_4236
NWI: Nwi_0647 Nwi_2396
NHA: Nham_1196
CCR: CC_2868
CCS: CCNA_02961
CAK: Caul_2713 Caul_4303
PZU: PHZ_c2601
RDE: RD1_4205
PDE: Pden_3556
MMR: Mmar10_1969 Mmar10_1974
HBA: Hbal_0198
SAL: Sala_1576 Sala_1580
MAG: amb0080 amb0092 amb0713
MGM: Mmc1_0562
BCG: BCG9842_B1724(pseI)
BAY: RBAM_035120(spsE)
BPU: BPUM_3432(spsE)
GKA: GK3123
GYC: GYMC61_3208
LSP: Bsph_1163
BBE: BBR47_53260(neuB)
SAG: SAG1161(neuB)
SAN: gbs1236(neuB)
SAK: SAK_1250(neuB)
SSU: SSU05_0578
SSV: SSU98_0582
SSB: SSUBM407_1280(neuB)
SSI: SSU0535(neuB)
SSS: SSUSC84_0517(neuB)
CTC: CTC01711
CNO: NT01CX_1784
CTH: Cthe_2229 Cthe_2641
CBO: CBO2680
CBA: CLB_2621 CLB_2661
CBH: CLC_2553 CLC_2594
CBY: CLM_3044 CLM_3086(pseI)
CBL: CLK_2067 CLK_2101 CLK_2105
CBK: CLL_A0832 CLL_A1556 CLL_A2336
CBB: CLD_1854 CLD_1885
CBI: CLJ_B2910 CLJ_B2947
CBT: CLH_0798 CLH_1466
CBF: CLI_2745 CLI_2775
CBE: Cbei_4278
CKL: CKL_2472
CKR: CKR_2186
AOE: Clos_2510
SWO: Swol_0210
DAU: Daud_0019 Daud_1772
HMO: HM1_1244
ERE: EUBREC_3247
MTA: Moth_0756
HOR: Hore_16950
SCO: SCO4881(2SCK8.07)
SMA: SAV_3373
SGR: SGR_2659
JDE: Jden_0843
TFU: Tfu_0010
SRO: Sros_1204
SVI: Svir_01550
ELE: Elen_1912 Elen_2425
TPP: TPASS_0562(spsE)
LIL: LA1609(nnaB1) LA1613(nnaB2)
LIC: LIC12169(sas) LIC12173(neuB)
LBJ: LBJ_1114(neuB-2)
LBL: LBL_1168(neuB-2)
LBI: LEPBI_I2027
LBF: LBF_1974(neuB-3)
BHY: BHWA1_01436(spsE)
ABA: Acid345_2841
SUS: Acid_2246
BVU: BVU_4040
SRU: SRU_0605(spsE)
CHU: CHU_2758(neuB)
DFE: Dfer_3363
PHE: Phep_3942
GFO: GFO_2016(neuB)
FJO: Fjoh_0305
FPS: FP1256(neuB)
FNU: FN1684
TAI: Taci_0643
SYW: SYNW0394 SYNW0448(neuB)
SYD: Syncc9605_2221
SYE: Syncc9902_0084 Syncc9902_0458
CYT: cce_4481
CYP: PCC8801_3448
CYN: Cyan7425_4942
CYH: Cyan8802_2668
NPU: Npun_R0684
PMI: PMT9312_1346
PMB: A9601_14241(spsE)
PMF: P9303_01101(spsE)
PMG: P9301_14081(spsE)
PMH: P9215_14811(spsE)
PMJ: P9211_12451(spsE)
PME: NATL1_08721(spsE)
CTE: CT0825
CPC: Cpar_0852
CCH: Cag_1072
CPH: Cpha266_1187
CLI: Clim_0797
PVI: Cvib_1025
PLT: Plut_1274
PPH: Ppha_0527 Ppha_1574
PAA: Paes_0910
CTS: Ctha_2574
RCA: Rcas_0774
PMX: PERMA_1627(neuB)
TNP: Tnap_0417
KOL: Kole_1281
TYE: THEYE_A0479
MMQ: MmarC5_0506
MAE: Maeo_0420
MBU: Mbur_1586
MHU: Mhun_3098
MSI: Msm_1539
HWA: HQ3519A(neuB)
HMU: Hmuk_1456
NMR: Nmar_0131
Taxonomy
Structures PDB: 1WVO  
Reference
  Authors
  Title
  Journal
  Organism
 1  [PMID:13971393]
BLACKLOW RS, WARREN L.
Biosynthesis of sialic acids by Neisseria meningitidis.
J. Biol. Chem. 237 (1962) 3520-6.
Neisseria meningitidis
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:9438985]
Komaki E, Ohta Y, Tsukada Y.
Purification and characterization of N-acetylneuraminate synthase
from Escherichia coli K1-M12.
Biosci. Biotechnol. Biochem. 61 (1997) 2046-50.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 2.5.1.56
IUBMB Enzyme Nomenclature: 2.5.1.56
ExPASy - ENZYME nomenclature database: 2.5.1.56
BRENDA, the Enzyme Database: 2.5.1.56
CAS: 37290-66-7
DBGET integrated database retrieval system