KEGG   ENZYME: 2.5.1.6Help
Entry
EC 2.5.1.6                  Enzyme                                 
Name methionine adenosyltransferase;
adenosylmethionine synthetase;
ATP-methionine adenosyltransferase;
methionine S-adenosyltransferase;
methionine-activating enzyme;
S-adenosyl-L-methionine synthetase;
S-adenosylmethionine synthase;
S-adenosylmethionine synthetase;
AdoMet synthetase
Class Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only
sub-subclass identified to date)
BRITE hierarchy
Sysname ATP:L-methionine S-adenosyltransferase
Reaction(IUBMB) ATP + L-methionine + H2O = phosphate + diphosphate +
S-adenosyl-L-methionine [RN:R00177]
Reaction(KEGG) R00177;
(other) R04771
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Substrate ATP [CPD:C00002];
L-methionine [CPD:C00073];
H2O [CPD:C00001]
Product phosphate [CPD:C00009];
diphosphate [CPD:C00013];
S-adenosyl-L-methionine [CPD:C00019]
Pathway PATH: ec00270  Cysteine and methionine metabolism
PATH: ec00450  Selenoamino acid metabolism
PATH: ec01070  Biosynthesis of plant hormones
PATH: ec01100  Metabolic pathways
Orthology KO: K00789  S-adenosylmethionine synthetase
Genes HSA: 27430(MAT2B) 4143(MAT1A) 4144(MAT2A)
PTR: 450555(MAT1A) 459363(MAT2A) 462245(MAT2B)
MCC: 695362(MAT2A) 698119(MAT2B) 700519(MAT1A)
MMU: 108645(Mat2b) 11720(Mat1a) 232087(Mat2a)
RNO: 171347(Mat2a) 25331(Mat1a) 683630(MGC94725)
CFA: 475770(MAT2A) 479301(MAT2B) 608788(MAT1A)
BTA: 527403(MAT2A) 541078(MAT1A) 614177(MAT2B)
SSC: 100156922 100217381(MAT2B)
ECB: 100052797 100059454 100067333
MDO: 100012907 100018803 100026003
OAA: 100077796 100082675
GGA: 416165(MAT2B) 423628(MAT1A)
TGU: 100222200 100226730
XLA: 379867(m(2)21ab) 734577
XTR: 100127858 395032(TEgg043h19.1) 549582(mat2b)
DRE: 323329(mat2a) 334195(mat1a) 541347 541483 678634
BFO: BRAFLDRAFT_57135 BRAFLDRAFT_73226
CIN: 100177357
SPU: 548618
DME: Dmel_CG2674(M(2)21AB)
DPO: Dpse_GA15421
DAN: Dana_GF14863
DER: Dere_GG24695
DPE: Dper_GL16618
DSE: Dsec_GM16715
DSI: Dsim_GD23001
DYA: Dyak_GE16582
DGR: Dgri_GH10060
DMO: Dmoj_GI16450
AGA: AgaP_AGAP009447
AAG: AaeL_AAEL004501
CQU: CpipJ_CPIJ001138
AME: 551102
NVI: 100121895
TCA: 658012
API: 100164058 100169241
ISC: IscW_ISCW004274 IscW_ISCW013817
CEL: C06E7.1 C06E7.3 C49F5.1(sams-1) T13A10.11(tag-32)
CBR: CBG15526 CBG19843 CBG19844
BMY: Bm1_09230
SMM: Smp_002080
NVE: NEMVE_v1g233095 NEMVE_v1g237177
HMG: 100199441
TAD: TRIADDRAFT_25365 TRIADDRAFT_25402 TRIADDRAFT_64181
ATH: AT2G36880(MAT3) AT3G17390(MTO3)
POP: POPTR_564333(AdoMet1) POPTR_729359(AdoMet_e2)
     POPTR_739535(AdoMet6) POPTR_834837(AdoMet4)
RCU: RCOM_1003190 RCOM_1343960 RCOM_1354270
VVI: 100243560(GSVIVT00028192001) 100244176(GSVIVT00019707001)
     100263678
OSA: 4325163(Os01g0293000) 4337733(Os05g0135700)
SBI: SORBI_03g011930(SORBIDRAFT_03g011930)
     SORBI_09g002840(SORBIDRAFT_09g002840)
ZMA: 100191838(cl2757_5c) 100194360 100279822
PPP: PHYPADRAFT_60419
CRE: CHLREDRAFT_182408(METM)
OLU: OSTLU_27381
CME: CMN227C
SCE: YDR502C(SAM2) YLR180W(SAM1)
AGO: AGOS_AFR692C
KLA: KLLA0C01782g
LTH: KLTH0F01782g
DHA: DEHA0E14751g
PIC: PICST_65158(SAM2)
PPA: PAS_chr3_0876
VPO: Kpol_2000p86
LEL: LELG_00896
ZRO: ZYRO0F17248g
CTP: CTRG_04100
CDU: CD36_10740
CGR: CAGL0B01122g CAGL0J08415g
YLI: YALI0B14509g
SPO: SPBC14F5.05c(sam1)
NCR: NCU02657
PAN: PODANSg4155
MGR: MGG_00383
FGR: FG00421.1
ANI: AN1222.2
AFM: AFUA_1G10630
AOR: AO090038000357
ANG: An08g02700
AFV: AFLA_069010
PCS: Pc16g04380
NFI: NFIA_015020
CIM: CIMG_08970
URE: UREG_03398
BFU: BC1G_04602
CNE: CNA04060
CNB: CNBA3860
LBC: LACBIDRAFT_188038
MPR: MPER_06682
MGL: MGL_3045
MBR: MONBRDRAFT_38559
DDI: DDB_0230070
EHI: EHI_174250
EDI: EDI_134010
PFA: PFI1090w
PFH: PFHG_01349
PYO: PY06246
PCB: PC000567.01.0
PBE: PB000151.03.0
PKN: PKH_071940
PVX: PVX_099525
TAN: TA11070
TPV: TP04_0893
BBO: BBOV_III009750
CPV: cgd7_2650
CHO: Chro.70301
TGO: TGME49_040690
TET: TTHERM_00444470
PTM: GSPATT00001423001 GSPATT00002622001 GSPATT00004929001
TBR: Tb927.6.4840 Tb927.6.4850 Tb927.6.4860 Tb927.6.4870
     Tb927.6.4880 Tb927.6.4890 Tb927.6.4900 Tb927.6.4910
     Tb927.6.4920
TCR: 506945.160 510445.50
LMA: LmjF30.3500 LmjF30.3520
LIF: LinJ30.3990
LBZ: LbrM30_V2.3550
GLA: GL50803_5659
TVA: TVAG_252200 TVAG_317070 TVAG_403830 TVAG_484900
PTI: PHATRDRAFT_bd913
TPS: THAPSDRAFT_39946(AMS2) THAPSDRAFT_8901
ECO: b2942(metK)
ECJ: JW2909(metK)
ECD: ECDH10B_3117(metK)
EBW: BWG_2664(metK)
ECE: Z4287(metK)
ECS: ECs3818
ECF: ECH74115_4244(metK)
ETW: ECSP_3913(metK)
ECG: E2348C_3195(metK)
ECC: c3528(metK) c4547
ECI: UTI89_C3331(metK)
ECP: ECP_2935
ECV: APECO1_2302 APECO1_3589(metK)
ECW: EcE24377A_3284(metK)
ECX: EcHS_A3099(metK)
ECM: EcSMS35_3084(metK)
ECY: ECSE_3210
ECL: EcolC_0772
ECK: EC55989_3235(metK)
ECQ: ECED1_3405(metK) ECED1_3471(metK)
ECR: ECIAI1_3075(metK)
ECT: ECIAI39_3360(metK)
ECZ: ECS88_3224(metK) ECS88_4662(metK)
EUM: ECUMN_3294(metK)
ELF: LF82_1326(metK)
EBL: B21_02735(metK)
EBD: ECBD_0798
EBR: ECB_02772(metK)
EOH: ECO103_3522(metK)
EOI: ECO111_3690(metK)
EOJ: ECO26_4041(metK)
EFE: EFER_2881(metK)
STY: STY3243(metK)
STT: t3002(metK)
SPT: SPA2953(metK)
SEK: SSPA2752
SPQ: SPAB_03853
SEI: SPC_3155(metK)
SEC: SC3030(metK)
SEH: SeHA_C3328(metK)
SEE: SNSL254_A3336(metK)
SEW: SeSA_A3263(metK)
SEA: SeAg_B3252(metK)
SED: SeD_A3433(metK)
SEG: SG2984(metK)
SET: SEN2933(metK)
SES: SARI_04556
STM: STM3090(metK)
YPE: YPO0931(metK)
YPK: y3314(metK)
YPM: YP_3512(metK)
YPA: YPA_0335
YPN: YPN_3127
YPG: YpAngola_A3347(metK)
YPP: YPDSF_0585
YPS: YPTB3203(metK)
YPI: YpsIP31758_0841(metK)
YPY: YPK_0843
YPB: YPTS_3335
YEN: YE3421(metK)
SFL: SF2933(metK)
SFX: S3137(metK)
SFV: SFV_2996(metK)
SSN: SSON_3096(metK)
SBO: SBO_3048(metK)
SBC: SbBS512_E3374(metK)
SDY: SDY_3130(metK)
ECA: ECA3920(metK)
PCT: PC1_3707
PWA: Pecwa_3905 Pecwa_4088
ETA: ETA_28260(metK)
PLU: plu3683(metK)
PAY: PAU_01087(metK) PAU_02393(mat)
BUC: BU408(metK)
BAS: BUsg393(metK)
BAP: BUAP5A_401(metK)
BAU: BUAPTUC7_402(metK)
WBR: WGLp316(metK)
SGL: SG2019
ENT: Ent638_3346
ESA: ESA_00400
CTU: Ctu_34770(metK)
KPN: KPN_03375(metK)
KPE: KPK_0734(metK)
KPU: KP1_4650(metK)
CKO: CKO_04317
SPE: Spro_3974
PMR: PMI2095(metK)
EIC: NT01EI_3376
ETR: ETAE_2964(metK)
BFL: Bfl252(metK)
BPN: BPEN_259(metK)
HDE: HDEF_0506(metK)
DDA: Dd703_0549
DDC: Dd586_3629
DZE: Dd1591_0506
HIN: HI1172(metX)
HIT: NTHI1340(metK)
HIP: CGSHiEE_06180
HIQ: CGSHiGG_09560
HDU: HD0569(metK)
HAP: HAPS_0500(metK)
HSO: HS_1623(metK)
HSM: HSM_0387
PMU: PM1027(metX)
MSU: MS0669(metK)
APL: APL_1080(metK)
APJ: APJL_1096(metK)
APA: APP7_1138
ASU: Asuc_0835
AAP: NT05HA_2370
AAT: D11S_2022
XFA: XF0392
XFT: PD1677(metK)
XFM: Xfasm12_1840
XFN: XfasM23_1771
XCC: XCC0761(metK)
XCB: XC_3471
XCA: xccb100_3592
XCV: XCV0865(metK)
XAC: XAC0813(metK)
XOO: XOO3791(metK)
XOM: XOO_3571
XOP: PXO_04686(metK)
SML: Smlt0780(metK)
SMT: Smal_0630
VCH: VC0472
VCO: VC0395_A0024(metK)
VCM: VCM66_0457(metK)
VCJ: VCD_001134
VVU: VV1_1536
VVY: VV2863
VPA: VP2606
VHA: VIBHAR_03568
VSP: VS_2655
VEX: VEA_002467
VFI: VF_0439(metK)
VFM: VFMJ11_0439(metK)
VSA: VSAL_I0552(metK)
PPR: PBPRA3134
PAE: PA0546(metK)
PAU: PA14_07090(metK)
PAP: PSPA7_0649(metK)
PAG: PLES_05441(metK)
PPU: PP_4967(metK)
PPF: Pput_4840
PPG: PputGB1_5016
PPW: PputW619_0499
PST: PSPTO_0383(metK)
PSB: Psyr_4794
PSP: PSPPH_4823(metK)
PFL: PFL_5788(metK)
PFO: Pfl01_5269
PFS: PFLU5709(metK)
PEN: PSEEN5026(metK)
PMY: Pmen_0454
PSA: PST_3926(metK)
CJA: CJA_0207(metK)
AVN: Avin_05530(metK)
PAR: Psyc_0828(metK)
PCR: Pcryo_0850
PRW: PsycPRwf_0879
ACI: ACIAD2037(metK)
ACB: A1S_1519
ABM: ABSDF2121(metK)
ABY: ABAYE2118(metK)
ABC: ACICU_01564
ABN: AB57_1761(metK)
ABB: ABBFA_001958(metK)
SON: SO_0929(metK)
SDN: Sden_1082
SFR: Sfri_0646
SAZ: Sama_2760
SBL: Sbal_0826
SBM: Shew185_3541
SBN: Sbal195_3660
SBP: Sbal223_3466
SLO: Shew_0751
SPC: Sputcn32_0871
SSE: Ssed_0873
SPL: Spea_0787
SHE: Shewmr4_0772
SHM: Shewmr7_3251
SHN: Shewana3_3354
SHW: Sputw3181_3302
SHL: Shal_0843
SWD: Swoo_0875
SWP: swp_4245
ILO: IL2215(metK)
CPS: CPS_1256(metK)
PHA: PSHAa0670(metK)
PAT: Patl_3331
SDE: Sde_0470
MAQ: Maqu_3042
AMC: MADE_03161
PIN: Ping_3227
TTU: TERTU_3976(metK)
CBU: CBU_2030(metK)
CBS: COXBURSA331_A0053(metK)
CBD: CBUD_2131(metK)
CBG: CbuG_2040(metK)
CBC: CbuK_2082(metK)
LPN: lpg2022(metK)
LPF: lpl1999(metK)
LPP: lpp2004(metK)
LPC: LPC_1506(metK)
MCA: MCA0139(metK-1) MCA0450(metK-2)
FTU: FTT_0149c(metK)
FTF: FTF0149c(metK)
FTW: FTW_0239(metK)
FTL: FTL_1739
FTH: FTH_1678(metK)
FTA: FTA_1842(metK)
FTM: FTM_0214(metK)
FTN: FTN_1563(metK)
FPH: Fphi_1051
TCX: Tcr_1821
NOC: Noc_2678
AEH: Mlg_2262
HHA: Hhal_0919 Hhal_1676
TGR: Tgr7_1179 Tgr7_2894
HNA: Hneap_0413
HCH: HCH_01533(metK)
CSA: Csal_0385
ABO: ABO_2617(metK)
MMW: Mmwyl1_4320
AHA: AHA_3124(metK)
ASA: ASA_1201(metK)
TAU: Tola_1255
DNO: DNO_0971(metK)
AFE: Lferr_0690
AFR: AFE_0532(metK)
BCI: BCI_0015(metK)
RMA: Rmag_0738
VOK: COSY_0683(metK)
KKO: Kkor_0237
NMA: NMA0663(metK)
NME: NMB1799(metK)
NMC: NMC0422(metK)
NMN: NMCC_0428(metK)
NMI: NMO_0378(metK)
NGO: NGO0106
NGK: NGK_0150
CVI: CV_0963(metK)
LHK: LHK_00579(metK)
RSO: RSc0134(metK)
RPI: Rpic_0036 Rpic_1694
RPF: Rpic12D_0030 Rpic12D_5306
REU: Reut_A0201 Reut_C6197
REH: H16_A0230(metK1) H16_A1975(metK2)
RME: Rmet_0156
CTI: RALTA_A0174(metK)
BMA: BMA3262(metK)
BMV: BMASAVP1_A2924(metK)
BML: BMA10229_A2165(metK)
BMN: BMA10247_3424(metK)
BPS: BPSL0212(metK)
BPM: BURPS1710b_0395(metK)
BPL: BURPS1106A_0211(metK)
BPD: BURPS668_0199(metK)
BPR: GBP346_A0113(metK)
BTE: BTH_I0174(metK)
BVI: Bcep1808_3166 Bcep1808_7266
BUR: Bcep18194_A6431
BCN: Bcen_2467
BCH: Bcen2424_3081
BCM: Bcenmc03_3099
BCJ: BCAL0509(metK)
BAM: Bamb_3129
BAC: BamMC406_2992
BMU: Bmul_3078
BMJ: BMULJ_00154(metK)
BXE: Bxe_A4371
BPH: Bphy_0078
BPY: Bphyt_0351
BGL: bglu_1g33680
PNU: Pnuc_2003
PNE: Pnec_1719
BPE: BP3071(metK)
BPA: BPP0192(metK)
BBR: BB0195(metK)
BPT: Bpet4781(metK)
BAV: BAV0158(metK)
RFR: Rfer_3880
POL: Bpro_0767
PNA: Pnap_0660
AAV: Aave_0979
AJS: Ajs_0705
VEI: Veis_4844
DAC: Daci_5604
DIA: Dtpsy_0683
VAP: Vapar_1126
CTT: CtCNB1_0654
MPT: Mpe_A3252
HAR: HEAR2952(metK)
MMS: mma_3198(metK)
LCH: Lcho_0126
NEU: NE0659(metK)
NET: Neut_1893
NMU: Nmul_A0036 Nmul_A2541
EBA: ebA3942(metK)
AZO: azo0589(metK)
DAR: Daro_0188
TBD: Tbd_2521
MFA: Mfla_0194
MMB: Mmol_2193
MEI: Msip34_0176
APP: CAP2UW1_4197
HPY: HP0197
HPJ: jhp0183(metK)
HPA: HPAG1_0191
HPS: HPSH_01010
HPG: HPG27_181
HPP: HPP12_0198(metK)
HPB: HELPY_0200(metK)
HHE: HH1540(metK)
HAC: Hac_0382(metK)
WSU: WS1994(metX)
TDN: Suden_1476 Suden_1777
CJE: Cj1096c(metK)
CJR: CJE1239(metK)
CJJ: CJJ81176_1114(metK)
CJU: C8J_1037(metK)
CJD: JJD26997_0626(metK)
CFF: CFF8240_0721(metK)
CCV: CCV52592_0703(metK)
CHA: CHAB381_1103(metK)
CCO: CCC13826_0068(metK)
CLA: Cla_1051(metK)
ABU: Abu_0445(metK)
SDL: Sdel_1624
NIS: NIS_0393(metK) NIS_1074
SUN: SUN_1452 SUN_2054(metK)
NAM: NAMH_0473(metK)
GSU: GSU0918 GSU1880(metK)
GME: Gmet_1290 Gmet_2549
GUR: Gura_1332 Gura_1448
GLO: Glov_0349
GBM: Gbem_1341 Gbem_1725 Gbem_3284
GEO: Geob_1656 Geob_2241 Geob_2346
GEM: GM21_0965 GM21_2943
PCA: Pcar_0186 Pcar_1928(metK)
PPD: Ppro_0044 Ppro_2839
DVU: DVU2449(metK)
DVL: Dvul_0786
DVM: DvMF_2941
DDE: Dde_1496
DDS: Ddes_2287
DMA: DMR_42050(metK)
DSA: Desal_1278
LIP: LI0726(metK)
DBA: Dbac_2303
DRT: Dret_2300
BBA: Bd0850(metK)
DPS: DP0801
DOL: Dole_2850
DAL: Dalk_3253
DAT: HRM2_23250(metK)
ADE: Adeh_0154
ACP: A2cp1_0172
AFW: Anae109_0159
ANK: AnaeK_0161
MXA: MXAN_6517(metK)
SCL: sce7312(metK)
HOH: Hoch_4271
SAT: SYN_00253 SYN_00417
SFU: Sfum_0367
RTY: RT0764(metK)
RFE: RF_1241 RF_1242
RAK: A1C_06040
RRI: A1G_06605
RRJ: RrIowa_1414
WOL: WD0136(metK)
WBM: Wbm0699
WRI: WRi_001150
WPI: WPa_1142(metK)
AMA: AM1288(metK)
AMF: AMF_973(metK)
ACN: ACIS_00113(metK)
APH: APH_0007(metK) APH_0058
ERU: Erum0070(metK)
ERW: ERWE_CDS_09520(metK)
ERG: ERGA_CDS_09440(metK)
ECN: Ecaj_0945
ECH: ECH_0018(metK)
NSE: NSE_0488(metK)
NRI: NRI_0461(metK)
PUB: SAR11_0387(metK)
MLO: mlr5545 mlr6115
MES: Meso_3924
PLA: Plav_3623
SME: SMc01109(metK)
SMD: Smed_0046
ATU: Atu0362(metK)
ATC: AGR_C_632
ARA: Arad_0663(metK)
AVI: Avi_0444(metK)
RET: RHE_CH00370(metK)
REC: RHECIAT_CH0000410(metK)
RLE: RL0389(metK)
RLT: Rleg2_0013
RLG: Rleg_0015
RHI: NGR_c00480(metK)
LAS: CLIBASIA_01540(metK)
BME: BMEI1970
BMF: BAB1_2160
BMB: BruAb1_2133(metK)
BMC: BAbS19_I20210
BMS: BR2160(metK)
BMT: BSUIS_A1997(metK)
BOV: BOV_2072(metK)
BCS: BCAN_A2202(metK)
BMR: BMI_I2181(metK)
OAN: Oant_0752
BJA: bll5945(metK) bll7989(mat)
BRA: BRADO5239(metK)
BBT: BBta_5699(metK)
RPA: RPA4016(metK)
RPB: RPB_1588
RPC: RPC_1177 RPC_4154
RPD: RPD_1596
RPE: RPE_4204
RPT: Rpal_4546
NWI: Nwi_2378
NHA: Nham_2753
OCA: OCAR_5319(metK)
BHE: BH02200(metK)
BQU: BQ02080(metK)
BBK: BARBAKC583_1249(metK)
BTR: Btr_0244(metK)
BGR: Bgr_02300(metK)
XAU: Xaut_1816
AZC: AZC_0014
MEX: Mext_3306
MEA: Mex_1p3521(metK)
MDI: METDI4098(metK)
MRD: Mrad2831_4493
MET: M446_5288
MPO: Mpop_3506
MCH: Mchl_3629
MNO: Mnod_5908
BID: Bind_1062
CCR: CC_0050
CCS: CCNA_00048(metK)
CAK: Caul_0027
PZU: PHZ_c3448(metK) PHZ_p0200
SIL: SPOA0011(metK)
SIT: TM1040_0193
RSP: RSP_3595(metK)
RSH: Rsph17029_3280
RSQ: Rsph17025_3877
RSK: RSKD131_3766
JAN: Jann_0706
RDE: RD1_3916(metK)
PDE: Pden_1873
DSH: Dshi_1012(metK)
MMR: Mmar10_2439
HNE: HNE_0786(metK)
HBA: Hbal_3057
ZMO: ZMO0273
ZMN: Za10_0947
NAR: Saro_0284
SAL: Sala_3139
SWI: Swit_3373
ELI: ELI_14285
GOX: GOX0866
GBE: GbCGDNIH1_2399
ACR: Acry_1054
GDI: GDI_1259(metK)
GDJ: Gdia_1970
APT: APA01_02930
RRU: Rru_A0917 Rru_A3776
RCE: RC1_2972(metK)
MAG: amb4469
MGM: Mmc1_3332
BSU: BSU30550(metK)
BHA: BH3300(metK)
BAN: BA5017(metK)
BAR: GBAA5017(metK)
BAA: BA_5437
BAT: BAS4660
BAH: BAMEG_5052(metK)
BAI: BAA_5031(metK)
BCE: BC4761
BCA: BCE_0391(metK) BCE_4914(metK)
BCZ: BCZK4517(metK)
BCR: BCAH187_A4904(metK)
BCB: BCB4264_A4877(metK)
BCU: BCAH820_4886(metK)
BCG: BCG9842_B0363(metK)
BCQ: BCQ_4582(metK)
BCX: BCA_4891(metK)
BCY: Bcer98_3437
BTK: BT9727_4500(metK)
BTL: BALH_4340(metK)
BWE: BcerKBAB4_4594
BLI: BL02632(metK)
BLD: BLi03196(metK)
BCL: ABC2878(metK)
BAY: RBAM_027570(metK)
BPU: BPUM_2686(metK)
OIH: OB2314(metK)
GKA: GK2849
GTN: GTNG_2750
GWC: GWCH70_2777
GYM: GYMC10_5884
GYC: GYMC61_0659
AFL: Aflv_0414(metK)
SAU: SA1608(metK)
SAV: SAV1790(metK)
SAW: SAHV_1775(metK)
SAM: MW1728(metK)
SAR: SAR1870
SAS: SAS1711
SAC: SACOL1837(metK)
SAB: SAB1645c
SAA: SAUSA300_1730(metK)
SAX: USA300HOU_1777(metK)
SAO: SAOUHSC_01909
SAJ: SaurJH9_1841
SAH: SaurJH1_1877
SAE: NWMN_1680(metK)
SAD: SAAV_1799(metK)
SEP: SE1458
SER: SERP1352(metK)
SHA: SH1139(metK)
SSP: SSP0976
SCA: Sca_1389(metK)
LMO: lmo1664(metK)
LMF: LMOf2365_1688(metK)
LMH: LMHCC_0901(metK)
LMC: Lm4b_01677(metK)
LIN: lin1773
LWE: lwe1683(metK)
LSP: Bsph_4251
ESI: Exig_2284
EAT: EAT1b_0742
MCL: MCCL_1498(metK)
BBE: BBR47_54050(metK)
PJD: Pjdr2_5777
AAC: Aaci_2574
LLA: L153408(metK)
LLK: LLKF_2095(metK)
LLC: LACR_2161
LLM: llmg_2160(metK)
SPY: SPy_0538 SPy_1359(metK)
SPZ: M5005_Spy_0445(metK1) M5005_Spy_1108(metK2)
SPM: spyM18_0604 spyM18_1372(metK)
SPG: SpyM3_0382 SpyM3_1034(metK)
SPS: SPs0826 SPs1471
SPH: MGAS10270_Spy0446(metK1) MGAS10270_Spy1178(metK2)
SPI: MGAS10750_Spy0465(metK1) MGAS10750_Spy1207(metK2)
SPJ: MGAS2096_Spy0464(metK1) MGAS2096_Spy1170(metK2)
SPK: MGAS9429_Spy0444(metK1) MGAS9429_Spy1152(metK2)
SPF: SpyM50751(metK) SpyM51419
SPA: M6_Spy0479 M6_Spy1082 M6_Spy1147
SPB: M28_Spy0433(metK1) M28_Spy1100(metK2)
SOZ: Spy49_0455 Spy49_1083c(metK)
SPN: SP_0762
SPD: SPD_0664(metK)
SPR: spr0671(metK)
SPW: SPCG_0712(metK)
SPX: SPG_0694(metK)
SNE: SPN23F_06840(metK)
SPV: SPH_0862(metK)
SNM: SP70585_0806(metK)
SJJ: SPJ_0699(metK)
SPP: SPP_0772(metK)
SNT: SPT_0775(metK)
SAG: SAG0831(metK)
SAN: gbs0849(metK)
SAK: SAK_0736(metK) SAK_0954(metK)
SMU: SMU.1573(metK)
STC: str1172(metK)
STL: stu1172(metK)
STE: STER_1135
SSA: SSA_1495(metK)
SSU: SSU05_1621
SSV: SSU98_1632
SSB: SSUBM407_1511(metK)
SSI: SSU1435(metK)
SSS: SSUSC84_1464(metK)
SGO: SGO_0987(metK)
SEQ: SZO_13190
SEZ: Sez_0680(metK)
SEU: SEQ_0706
SUB: SUB1211(metK)
SDS: SDEG_1371(metK2)
LPL: lp_1301(metK)
LPJ: JDM1_1101
LJO: LJ0677
LJF: FI9785_519(metK)
LAC: LBA1622(metK)
LSA: LSA0468(metK)
LSL: LSL_0441(metK)
LDB: Ldb1575(metK)
LBU: LBUL_1455
LBR: LVIS_1523
LCA: LSEI_0877
LCB: LCABL_09430(metK)
LGA: LGAS_0456
LRE: Lreu_1296
LRF: LAR_1229
LHE: lhv_1731
LFE: LAF_1358
LRH: LGG_00842(metK)
LRL: LC705_00893(metK)
PPE: PEPE_0641
EFA: EF0784(metK)
OOE: OEOE_0838
LME: LEUM_1697
LCI: LCK_01370(metK)
CAC: CAC2856(metK)
CPE: CPE2177(metK)
CPF: CPF_2435(metK)
CPR: CPR_2145(metK)
CTC: CTC00321
CNO: NT01CX_0516(metK)
CTH: Cthe_2251
CDF: CD0130(metE)
CDC: CD196_0142(metE)
CDL: CDR20291_0129(metE)
CBO: CBO0168(metE)
CBA: CLB_0208(metK)
CBH: CLC_0222(metK)
CBY: CLM_0216(metK)
CBL: CLK_3346(metK)
CBK: CLL_A0515(metK)
CBB: CLD_0612(metK)
CBI: CLJ_B0212(metK_1)
CBT: CLH_0507(metK)
CBF: CLI_0231(metK)
CBE: Cbei_0428 Cbei_4050
CKL: CKL_1633(metK1) CKL_2650(metK2) CKL_3674(metK3)
CKR: CKR_1518 CKR_2348 CKR_3244
CPY: Cphy_3874
CCE: Ccel_0087 Ccel_2843
AMT: Amet_0716 Amet_4040
AOE: Clos_2531
STH: STH118
SWO: Swol_1234
VPR: Vpar_0845
ATE: Athe_0686
DSY: DSY2726
DHD: Dhaf_3891
DRM: Dred_3096
DAE: Dtox_3981
PTH: PTH_2759(metK)
DAU: Daud_2084
HMO: HM1_2130(metK)
FMA: FMG_1158
APR: Apre_0177
EEL: EUBELI_00171
ERE: EUBREC_0463
TTE: TTE0488(metK)
TEX: Teth514_0445 Teth514_1243
TPD: Teth39_1790
CHY: CHY_0138(metK)
MTA: Moth_0894
ADG: Adeg_1071
CSC: Csac_0857
CPO: COPRO5265_0977(metK)
NTH: Nther_2330
HOR: Hore_09860
MGE: MG_047(metX)
MPN: MPN060(metX)
MPU: MYPU_7020(metK)
MPE: MYPE940(metK)
MGA: MGA_0128(metK)
MMY: MSC_0492(metK)
MMO: MMOB3090(metK)
MHY: mhp450(metK)
MHJ: MHJ_0448(metK)
MHP: MHP7448_0451(metK)
MSY: MS53_0610(metK)
MCP: MCAP_0478(metK)
MAA: MAG_5800(metK)
MAT: MARTH_orf534(metK)
MCO: MCJ_003760(metK)
MHO: MHO_3640(metK)
UUR: UU412(metK)
UPA: UPA3_0429(metK)
UUE: UUR10_0456(metK)
PML: ATP_00296(metK)
ACL: ACL_0328(metK1) ACL_0600(metK2)
MFL: Mfl240
MTU: Rv1392(metK)
MTC: MT1437(metK)
MRA: MRA_1401(metK)
MTF: TBFG_11421
MTB: TBMG_02588(TBMG_02588.1)
MBO: Mb1427(metK)
MBB: BCG_1453(metK)
MBT: JTY_1428(metK)
MLE: ML0544(metK)
MLB: MLBr_00544(metK)
MPA: MAP1126(metK)
MAV: MAV_3382(metK)
MSM: MSMEG_3055(metK)
MUL: MUL_1791(metK)
MVA: Mvan_2670
MGI: Mflv_3737
MAB: MAB_2820c
MMC: Mmcs_2373
MKM: Mkms_2420
MJL: Mjls_2414
MMI: MMAR_2205(metK)
CGL: NCgl1541(cgl1603)
CGB: cg1806(metK)
CGT: cgR_1652
CEF: CE1723(metK)
CDI: DIP1325(metK)
CJK: jk1016(metK)
CUR: cur_0975
CAR: cauri_1185(metK2)
CKP: ckrop_0984
NFA: nfa36130(metK)
RHA: RHA1_ro07158(metK)
RER: RER_30110(metK)
ROP: ROP_69390(metK)
GBR: Gbro_2348
SCO: SCO1476(metK)
SMA: SAV_6874(metK)
SGR: SGR_6058
TWH: TWT360(metK)
TWS: TW409(metK)
LXX: Lxx11150(metK)
CMI: CMM_1777(metK)
CMS: CMS_2024(metK)
ART: Arth_2256
AAU: AAur_2259(metK)
ACH: Achl_1993
RSA: RSal33209_1956
KRH: KRH_13260(metK)
MLU: Mlut_12520
BCV: Bcav_2045
BFA: Bfae_14830
JDE: Jden_1315
KSE: Ksed_12750
XCE: Xcel_1718
PAC: PPA1193 PPA1587
NCA: Noca_2439
TFU: Tfu_1065
TCU: Tcur_3004
SRO: Sros_2818
FRA: Francci3_2993 Francci3_3192
FRE: Franean1_1716
FAL: FRAAL4932(metK) FRAAL5227(metK)
ACE: Acel_1290
NML: Namu_4159
KRA: Krad_2989
SEN: SACE_2103(metK) SACE_3900(metK)
SVI: Svir_15650 Svir_27040
AMI: Amir_3103 Amir_5235
STP: Strop_1136 Strop_1864
SAQ: Sare_1857 Sare_3663
CAI: Caci_5342
BLO: BL1786(metK)
BLJ: BLD_1963(metK)
BLN: Blon_2136
BAD: BAD_0541(metK)
BLA: BLA_1159(metK)
BLC: Balac_0631
BLT: Balat_0631
RXY: Rxyl_1470
AFO: Afer_1692
CCU: Ccur_08430
SHI: Shel_09870
APV: Apar_0501
ELE: Elen_1306
BBU: BB0376
BBZ: BbuZS7_0378(metK)
BGA: BG0375(metK)
BAF: BAPKO_0385(metK)
BTU: BT0376
BHR: BH0376
BDU: BDU_371(metK)
BRE: BRE_375(metK)
TPA: TP0794
TPP: TPASS_0794(metK)
TDE: TDE2470(metK)
LIL: LA2633(metK)
LIC: LIC11354(metK)
LBJ: LBJ_1645(metK)
LBL: LBL_1864(metK)
LBI: LEPBI_I2968(metK)
LBF: LBF_2866(metK)
BHY: BHWA1_02419(metK)
ABA: Acid345_3661 Acid345_4566
ACA: ACP_1783(metK)
SUS: Acid_1686 Acid_5274
BTH: BT_3219
BFR: BF0061
BFS: BF0072(metK)
BVU: BVU_1184
PGI: PG1896(metK)
PGN: PGN_1827
PDI: BDI_2403
APS: CFPG_599
SRU: SRU_2755(metK)
RMR: Rmar_2688
CHU: CHU_3400(metK)
DFE: Dfer_3203
CPI: Cpin_3691
PHE: Phep_4094
GFO: GFO_0314(metK)
FJO: Fjoh_1489
FPS: FP0268(metK)
FBA: FIC_00170
COC: Coch_0271
RBI: RB2501_03155
BBL: BLBBGE_345(metK)
BPI: BPLAN_295(metK)
FSU: Fisuc_2786
FNU: FN0355
LBA: Lebu_0761
STR: Sterm_1727
SMF: Smon_0415
OTE: Oter_3855
MIN: Minf_0670(metK)
AMU: Amuc_1068
GAU: GAU_1484(metK)
RBA: RB5444(metK)
EMI: Emin_1246
RSD: TGRD_621
TAI: Taci_0660
SYN: sll0927(metX)
SYW: SYNW1987(metK)
SYC: syc1641_d(metK)
SYF: Synpcc7942_2463
SYD: Syncc9605_0466
SYE: Syncc9902_1869
SYG: sync_0529(metK)
SYR: SynRCC307_0413(metK)
SYX: SynWH7803_0513(metK)
SYP: SYNPCC7002_A1714(metK)
CYA: CYA_1186(metK)
CYB: CYB_2590(metK)
TEL: tll0978
MAR: MAE_45970
CYT: cce_1822(metK)
CYP: PCC8801_1832 PCC8801_3004
CYC: PCC7424_3478
CYN: Cyan7425_4132
CYH: Cyan8802_1858 Cyan8802_3115
GVI: gll2577
ANA: all3244 alr4124
NPU: Npun_F2753
AVA: Ava_0780 Ava_4899
PMA: Pro0349(metK)
PMM: PMM0311(metK)
PMT: PMT1670(metK)
PMN: PMN2A_1687
PMI: PMT9312_0317
PMB: A9601_03351(metK)
PMC: P9515_03441(metK)
PMF: P9303_22181(metK)
PMG: P9301_03361(metK)
PMH: P9215_03361(metK)
PMJ: P9211_03451
PME: NATL1_04001(metK)
TER: Tery_4661
AMR: AM1_5701(metK)
CTE: CT0540(metK) CT0722(metK)
CPC: Cpar_0689 Cpar_1534
CCH: Cag_1547
CPH: Cpha266_0746 Cpha266_0922
CPB: Cphamn1_1640 Cphamn1_1822
CLI: Clim_0510 Clim_1641
PVI: Cvib_1121
PLT: Plut_0551 Plut_0672
PPH: Ppha_2094
PAA: Paes_0689 Paes_0808
CTS: Ctha_1913
DET: DET0067(metK-1) DET0512(metK-2)
DEH: cbdb_A476(metK)
DEB: DehaBAV1_0488
DEV: DhcVS_453(metK)
RRS: RoseRS_0489 RoseRS_0919
RCA: Rcas_0160 Rcas_1562
CAU: Caur_3020
CAG: Cagg_3565
CHL: Chy400_3266
HAU: Haur_2353
TRO: trd_0917(metK)
STI: Sthe_1122
DRA: DR_0640
DGE: Dgeo_0287
DDR: Deide_19790(metK)
TTH: TTC1279
TTJ: TTHA1642
AAE: aq_1154(metK) aq_1226
HYA: HY04AAS1_0161 HY04AAS1_0745
SUL: SYO3AOP1_0095 SYO3AOP1_1276
SAF: SULAZ_0897(metK) SULAZ_1612
PMX: PERMA_0400 PERMA_0559(metK)
TMA: TM1658
TPT: Tpet_1133
TLE: Tlet_0786
TRQ: TRQ2_1171
TNA: CTN_0729
TNP: Tnap_1148
TME: Tmel_1756
TAF: THA_108(metK)
FNO: Fnod_0125
PMO: Pmob_1383
KOL: Kole_0285
DTH: DICTH_0772
DTU: Dtur_0921
TYE: THEYE_A0112(metK)
TTR: Tter_1186
MJA: MJ1208
MFE: Mefer_0283
MVU: Metvu_1344
MMP: MMP1640
MMQ: MmarC5_1768
MMX: MmarC6_1031
MMZ: MmarC7_0913
MAE: Maeo_0461
MVN: Mevan_0945
MAC: MA0216(mat) MA0962(mat)
MBA: Mbar_A1313 Mbar_A1862
MMA: MM_1502 MM_2076
MBU: Mbur_1330
MTP: Mthe_0726 Mthe_1403
MHU: Mhun_0923
MLA: Mlab_0490
MEM: Memar_0838
MBN: Mboo_1064
MPL: Mpal_1744
MPD: MCP_0625 MCP_1463(metK)
MTH: MTH1376
MST: Msp_1470(mat)
MSI: Msm_1340
MKA: MK1508
AFU: AF0050
HAL: VNG1297C
HSL: OE2857F(mat)
HMA: rrnAC1233(metK)
HWA: HQ2584A(metK)
NPH: NP3100A(mat)
HLA: Hlac_1394
HUT: Huta_0513
HMU: Hmuk_2306
TAC: Ta0059
TVO: TVN0015
PTO: PTO0744
PHO: PH1824
PAB: PAB2094
PFU: PF1866
TKO: TK0545
TON: TON_0560
TGA: TGAM_0577(mat)
TSI: TSIB_0975
RCI: RCIX2255(mat) RRC334(metK)
APE: APE_1596(mat)
SMR: Smar_1298
IHO: Igni_0158
DKA: DKAM_0024
HBU: Hbut_0083
SSO: SSO0199(mat)
STO: ST0235
SAI: Saci_0798(matT)
SIS: LS215_2098
SIA: M1425_1935
SIM: M1627_2013
SID: M164_1943
SIY: YG5714_2057
SIN: YN1551_0861
MSE: Msed_0231
PAI: PAE0677
PIS: Pisl_0691
PCL: Pcal_2103
PAS: Pars_2333
CMA: Cmaq_0865
TNE: Tneu_1975
TPE: Tpen_0737
NMR: Nmar_0085
KCR: Kcr_0023
Taxonomy
Structures PDB: 1FUG  1MXA  1MXB  1MXC  1O90  1O92  1O93  1O9T  1P7L  1QM4  
     1RG9  1XRA  1XRB  1XRC  2OBV  2P02  3IML  
Reference
  Authors
  Title

  Journal
  Organism

 1  [PMID:13084611]
CATONI GL.
S-Adenosylmethionine; a new intermediate formed enzymatically from
L-methionine and adenosinetriphosphate.
J. Biol. Chem. 204 (1953) 403-16.
Rattus norvegicus [GN:rno], Sus scofa [GN:ssc], Oryctolagus
cuniculus
Reference
  Authors
  Title


  Journal
  Organism
 2  [PMID:13416303]
CANTONI GL, DURELL J.
Activation of methionine for transmethylation.  II.  The
methionine-activating enzyme; studies on the mechanism of the
reaction.
J. Biol. Chem. 225 (1957) 1033-48.
Rattus norvegicus [GN:rno], Oryctolagus cuniculus
Reference
  Authors
  Title

  Journal
  Organism
 3  [PMID:13538985]
MUDD SH, CANTONI GL.
Activation of methionine for transmethylation. III. The
methionine-activating enzyme of Bakers' yeast.
J. Biol. Chem. 231 (1958) 481-92.
Saccharomyces cerevisiae [GN:sce]
Other DBs ExplorEnz - The Enzyme Database: 2.5.1.6
IUBMB Enzyme Nomenclature: 2.5.1.6
ExPASy - ENZYME nomenclature database: 2.5.1.6
BRENDA, the Enzyme Database: 2.5.1.6
CAS: 9012-52-6
DBGET integrated database retrieval system