KEGG   ENZYME: 2.6.1.12Help
Entry
EC 2.6.1.12                 Enzyme                                 

Name alanine---oxo-acid transaminase;
L-alanine-alpha-keto acid aminotransferase;
leucine-alanine transaminase;
alanine-keto acid aminotransferase;
alanine-oxo acid aminotransferase
Class Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname L-alanine:2-oxo-acid aminotransferase
Reaction(IUBMB) L-alanine + a 2-oxo acid = pyruvate + an L-amino acid [RN:R01261]
Reaction(KEGG) R01261 > R00400
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Substrate L-alanine [CPD:C00041];
2-oxo acid [CPD:C00161]
Product pyruvate [CPD:C00022];
L-amino acid [CPD:C00151]
Cofactor Pyridoxal phosphate [CPD:C00018]
Comment A pyridoxal-phosphate protein.
Pathway PATH: ec00250  Alanine, aspartate and glutamate metabolism
Reference
  Authors
  Title
  Journal
  Organism
1  [PMID:13084587]
ALTENBERN RA, HOUSEWRIGHT RD.
Transaminases in smooth Brucella abortus, strain 19.
J. Biol. Chem. 204 (1953) 159-67.
Brucella abortus [GN:bmb]
Reference
  Authors
  Title
  Journal
  Organism
2  [PMID:13363834]
ROWSELL EV.
Transaminations with pyruvate and other alpha-keto acids.
Biochem. J. 64 (1956) 246-52.
Rattus norvegicus [GN:rno]
Reference
  Authors
  Title
  Journal
  Organism
3  [PMID:13385257]
SALLACH HJ.
Formation of serine hydroxypryuvate and L-alanine.
J. Biol. Chem. 223 (1956) 1101-8.
Canis familiaris [GN:cfa]
Reference
  Authors
  Title
  Journal
  Organism
4  [PMID:13174595]
WILSON DG, KING KW, BURRIS RH.
Transamination reactions in plants.
J. Biol. Chem. 208 (1954) 863-74.
Hordeum vulgare, Lupinus albus
Other DBs ExplorEnz - The Enzyme Database: 2.6.1.12
IUBMB Enzyme Nomenclature: 2.6.1.12
ExPASy - ENZYME nomenclature database: 2.6.1.12
BRENDA, the Enzyme Database: 2.6.1.12
CAS: 9030-41-5

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