| Entry |
|
|---|
| Name |
ornithine aminotransferase;
ornithine delta-transaminase;
L-ornithine:alpha-ketoglutarate delta-aminotransferase;
OAT;
L-ornithine 5-aminotransferase;
L-ornithine aminotransferase;
ornithine 5-aminotransferase;
ornithine transaminase;
ornithine-alpha-ketoglutarate aminotransferase;
ornithine-2-oxoacid aminotransferase;
ornithine-keto acid aminotransferase;
ornithine-keto acid transaminase;
ornithine-ketoglutarate aminotransferase;
ornithine-oxo acid aminotransferase;
ornithine:alpha-oxoglutarate transaminase;
ornithine---oxo-acid transaminase |
|---|
| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
 |
|---|
| Sysname |
L-ornithine:2-oxo-acid aminotransferase |
|---|
| Reaction(IUBMB) |
L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino
acid [RN:R01343] |
|---|
| Reaction(KEGG) |
R01343 > R00667;
(other) R00668
 |
|---|
| Substrate |
L-ornithine [CPD:C00077];
2-oxo acid [CPD:C00161] |
|---|
| Product |
L-glutamate 5-semialdehyde [CPD:C01165];
L-amino acid [CPD:C00151] |
|---|
| Cofactor |
Pyridoxal phosphate [CPD:C00018] |
|---|
| Comment |
A pyridoxal-phosphate protein. |
|---|
| Pathway |
PATH: ec00330 Arginine and proline metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00819 ornithine--oxo-acid transaminase |
|---|
| Genes |
HSA: 4942(OAT)
PTR: 450803(OAT)
MCC: 693970(OAT)
MMU: 18242(Oat)
RNO: 64313(Oat)
CFA: 477858(OAT)
BTA: 505323(OAT)
SSC: 100156865
ECB: 100050199
MDO: 100012349
OAA: 100085298 100085429
GGA: 426430(OAT)
TGU: 100218583
XLA: 379754(oat) 446525(oat)
XTR: 549690(oat)
DRE: 572518
CIN: 100176122
DME: Dmel_CG8782(Oat)
DPO: Dpse_GA21318
DAN: Dana_GF10718(Dana_Oat)
DER: Dere_GG13385
DPE: Dper_GL20876
DSE: Dsec_GM16950
DSI: Dsim_GD12261 Dsim_GD12262
DYA: Dyak_GE22477
DGR: Dgri_GH14619
DMO: Dmoj_GI13506
AGA: AgaP_AGAP004793
AAG: AaeL_AAEL005289
CQU: CpipJ_CPIJ004401
AME: 410582 410583
NVI: 100119865 100119896
TCA: 661018
API: 100168809
ISC: IscW_ISCW024076
CEL: C16A3.10
CBR: CBG09115
SMM: Smp_000660
NVE: NEMVE_v1g159041
HMG: 100199538
TAD: TRIADDRAFT_28327
ATH: AT5G46180
POP: POPTR_1093547
RCU: RCOM_0631280
VVI: 100233101
OSA: 4333554(Os03g0643300)
SBI: SORBI_01g013600(SORBIDRAFT_01g013600)
ZMA: 100191445
PPP: PHYPADRAFT_166852
CRE: CHLREDRAFT_195386(OTA1)
CME: CML323C
SCE: YLR438W(CAR2)
AGO: AGOS_AER123W
KLA: KLLA0B05247g
LTH: KLTH0B00220g KLTH0D16038g
DHA: DEHA0F06556g
PIC: PICST_77538(CAR2)
PPA: PAS_chr3_0410
VPO: Kpol_520p40
LEL: LELG_04331
ZRO: ZYRO0B14058g
CAL: CaO19.13086(CAR2) CaO19.5641(CAR2)
CTP: CTRG_00013
CDU: CD36_40230
CGR: CAGL0M00880g
YLI: YALI0C04433g
SPO: SPBC21C3.08c
NCR: NCU00194
PAN: PODANSg5491
MGR: MGG_06392
FGR: FG02304.1 FG04673.1 FG05546.1
ANI: AN1810.2
AFM: AFUA_4G09140 AFUA_8G02150
AOR: AO090023000546 AO090023000628
ANG: An04g04130 An11g08870
AFV: AFLA_109620 AFLA_110430
PCS: Pc18g03600
NFI: NFIA_044270 NFIA_095910 NFIA_107030
CIM: CIMG_07962
URE: UREG_02253
SSL: SS1G_11230
BFU: BC1G_05433
CNE: CNL04880
CNB: CNBI1960
LBC: LACBIDRAFT_184382
MPR: MPER_08627
UMA: UM03169.1
MGL: MGL_2924
MBR: MONBRDRAFT_38602
DDI: DDB_0231478(oatA)
PFA: PFF0435w
PFD: PFDG_00902
PFH: PFHG_01686
PYO: PY00104
PCB: PC001183.02.0
PBE: PB000618.00.0
PKN: PKH_114040
PVX: PVX_113600
TGO: TGME49_069110
TET: TTHERM_01049320
PTM: GSPATT00021115001 GSPATT00023021001
PTI: PHATRDRAFT_27726(OAT)
TPS: THAPSDRAFT_27892
MCA: MCA0809
FPH: Fphi_0554
NOC: Noc_1711
RSO: RSc0159
RPI: Rpic_0052
RPF: Rpic12D_0049
BPE: BP0539(rocD)
BPA: BPP0748(rocD)
BBR: BB0834(rocD)
MPT: Mpe_A2115
HAR: HEAR0122(rocD)
MMS: mma_0147(rocD)
NEU: NE0142
NET: Neut_2174
EBA: ebA3609(rocD)
AZO: azo0376
DSA: Desal_2766 Desal_3327
DAT: HRM2_23580(rocD1)
MXA: MXAN_7377(rocD)
MLO: mll1261
ARA: Arad_4277(rocD) Arad_7871
RET: RHE_CH03852(rocD)
REC: RHECIAT_CH0004133(rocD)
RLE: RL4385(rocD)
RLT: Rleg2_3630(rocD)
RLG: Rleg_3918
RHI: NGR_c30830(rocD)
BME: BMEII0441
BMI: BMEA_B0830
BMF: BAB2_0385
BMB: BruAb2_0380
BMC: BAbS19_II03620
BMS: BRA0851
BMT: BSUIS_B0844
BOV: BOV_A0799
BCS: BCAN_B0868(ygjG)
BMR: BMI_II845
OAN: Oant_2968
BJA: bll2855(rocD) blr3010
BRA: BRADO2635
BBT: BBta_2975
RPC: RPC_1728
RPT: Rpal_4253
NWI: Nwi_2263 Nwi_2516
NHA: Nham_2676 Nham_3111
OCA: OCAR_6663
BID: Bind_2814 Bind_3215
MSL: Msil_1660 Msil_2885
PZU: PHZ_c3111(rocD)
GBE: GbCGDNIH1_1948(rocD)
RRU: Rru_A3466(rocD)
RCE: RC1_0557(rocD)
BSU: BSU40340(rocD)
BHA: BH3943(rocD)
BAN: BA1154(rocD)
BAR: GBAA1154(rocD)
BAA: BA_1699
BAT: BAS1071(rocD)
BAH: BAMEG_3428(rocD)
BAI: BAA_1236(rocD)
BCE: BC1149(rocD)
BCA: BCE_1256(rocD)
BCZ: BCZK1050(rocD)
BCR: BCAH187_A1307(rocD)
BCB: BCB4264_A1204(rocD)
BCU: BCAH820_1231(rocD)
BCG: BCG9842_B4137(rocD)
BCQ: BCQ_1211(rocD)
BCX: BCA_1193(rocD)
BCY: Bcer98_0869(rocD)
BTK: BT9727_1052(rocD)
BTL: BALH_1015(rocD)
BWE: BcerKBAB4_1053(rocD)
BLI: BL01737(rocD)
BLD: BLi00422(rocD)
BCL: ABC0017(rocD)
BAY: RBAM_037250(rocD)
BPU: BPUM_3060(rocD)
OIH: OB2287(rocD)
GKA: GK0188(rocD)
GTN: GTNG_0170(rocD)
GWC: GWCH70_0686
GYM: GYMC10_1997
GYC: GYMC61_1044
AFL: Aflv_2206(rocD)
SAW: SAHV_0952(rocD)
SAX: USA300HOU_0916(rocD)
SAO: SAOUHSC_00894(rocD)
SAJ: SaurJH9_0957(rocD)
SAH: SaurJH1_0976(rocD)
SAE: NWMN_0827(rocD)
SAD: SAAV_0918(rocD)
SCA: Sca_0565(rocD)
LSP: Bsph_0623(rocD)
ESI: Exig_0504(rocD)
EAT: EAT1b_2277
MCL: MCCL_0583
BBE: BBR47_22460(rocD)
PJD: Pjdr2_3902
AAC: Aaci_0322
CCE: Ccel_1814
NTH: Nther_1150
MTU: Rv2321c(rocD2) Rv2322c(rocD1)
MRA: MRA_2341(rocD2) MRA_2342(rocD1)
MTF: TBFG_12344 TBFG_12345
MTB: TBMG_01657(TBMG_01657.1) TBMG_01658(TBMG_01658.1)
MBO: Mb2348c(rocD2) Mb2349c(rocD1)
MBB: BCG_2342c(rocD2) BCG_2343c(rocD1)
MBT: JTY_2336(rocD2) JTY_2337(rocD1)
MPA: MAP2094c(rocD1)
MAV: MAV_2086(rocD)
MSM: MSMEG_1413(rocD)
MUL: MUL_1243(rocD)
MVA: Mvan_1287
MGI: Mflv_5071
MAB: MAB_3841
MKM: Mkms_1010
MJL: Mjls_1020
MMI: MMAR_3622(rocD)
RHA: RHA1_ro06169(rocD)
ROP: ROP_62290(rocD)
SCO: SCO1223(2SCG58.23) SCO1284(2SCG18.31c)
SMA: SAV_2285(rocD3) SAV_3420(rocD1) SAV_7112(rocD2)
SGR: SGR_2290 SGR_2703 SGR_959
CMI: CMM_0630(rocD)
CMS: CMS_0488
BCV: Bcav_0886
KSE: Ksed_21320
NCA: Noca_4863
TFU: Tfu_2247
TCU: Tcur_1135
SRO: Sros_2330
ACE: Acel_0454
NML: Namu_3540
SEN: SACE_1875(rocD)
SVI: Svir_23960
AMI: Amir_1586
STP: Strop_3677
SAQ: Sare_4053
CAI: Caci_7208 Caci_7971
ABA: Acid345_1822
BVU: BVU_2244
PGI: PG1271
PGN: PGN_1403
PDI: BDI_2673
CHU: CHU_0647(hemL)
DFE: Dfer_3421
CPI: Cpin_4031
GFO: GFO_1886(oat)
FJO: Fjoh_4657
FPS: FP0739(rocD)
FBA: FIC_02150
COC: Coch_1494
RBI: RB2501_16159
GAU: GAU_3903(rocD)
TAI: Taci_0029
MAR: MAE_31780(argD)
AVA: Ava_B0165
DRA: DR_1415
DGE: Dgeo_1219
DDR: Deide_11260 Deide_2p01410
TTH: TTC0553
TTJ: TTHA0909
TLE: Tlet_0944
 |
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| Structures |
PDB: 1GBN 1OAT 1Z7D 2BYJ 2BYL 2CAN 2OAT |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13032071]
FINCHAM JR.
Ornithine transaminase in Neurospora and its relation to the
biosynthesis of proline.
Biochem. J. 53 (1953) 313-20.
Neurospora crassa [GN:ncr] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:14244051]
KATUNUMA N, MATSUDA Y, TOMINO I.
STUDIES ON ORNITHINE-KETOACID TRANSAMINASE. I. PURIFICATION AND
PROPERTIES.
J. Biochem. 56 (1964) 499-503.
Rattus norvegicus [GN:rno], Neurospora crassa [GN:ncr], Escherichia
coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:13143017]
MEISTER A.
Enzymatic transamination reactions involving arginine and ornithine.
J. Biol. Chem. 206 (1954) 587-96.
Neurospora crassa [GN:ncr] |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:5783831]
Peraino C, Bunville LG, Tahmisian TN.
Chemical, physical, and morphological properties of ornithine
Aminotransferase from rat liver.
J. Biol. Chem. 244 (1969) 2241-9.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
|
5 [PMID:14826840]
QUASTEL JH, WITTY R.
Ornithine transaminase.
Nature. 167 (1951) 556. |
|---|
Reference
Authors
Title
Journal
Organism
|
6 [PMID:14284729]
STRECKER HJ.
PURIFICATION AND PROPERTIES OF RAT LIVER ORNITHINE
DELTA-TRANSAMINASE.
J. Biol. Chem. 240 (1965) 1225-30.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.6.1.13
IUBMB Enzyme Nomenclature: 2.6.1.13
ExPASy - ENZYME nomenclature database: 2.6.1.13
BRENDA, the Enzyme Database: 2.6.1.13
CAS: 9030-42-6 |
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