KEGG   ENZYME: 2.6.1.15Help
Entry
EC 2.6.1.15                 Enzyme                                 

Name
glutamine---pyruvate transaminase;
glutaminase II;
L-glutamine transaminase L;
glutamine-oxo-acid transaminase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-glutamine:pyruvate aminotransferase
Reaction(IUBMB)
L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine [RN:R00576]
Reaction(KEGG)
Substrate
L-glutamine [CPD:C00064];
pyruvate [CPD:C00022]
Product
2-oxoglutaramate [CPD:C00940];
L-alanine [CPD:C00041]
Comment
A pyridoxal-phosphate protein. L-Methionine can act as donor; glyoxylate can act as acceptor.
History
EC 2.6.1.15 created 1961
Pathway
Alanine, aspartate and glutamate metabolism
Reference
1  [PMID:5059882]
  Authors
Cooper JL, Meister A.
  Title
Isolation and properties of highly purified glutamine transaminase.
  Journal
Biochemistry. 11 (1972) 661-71.
Reference
2  [PMID:13201566]
  Authors
MEISTER A.
  Title
Studies on the mechanism and specificity of the glutamine-alpha-keto acid transamination-deamidation reaction.
  Journal
J. Biol. Chem. 210 (1954) 17-35.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9030-44-8

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