KEGG   ENZYME: 2.6.1.26Help
Entry
EC 2.6.1.26                 Enzyme                                 

Name
thyroid-hormone transaminase;
3,5-dinitrotyrosine transaminase;
thyroid hormone aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase
Reaction(IUBMB)
L-3,5,3'-triiodothyronine + 2-oxoglutarate = 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-2-oxopropanoate + L-glutamate [RN:R03952]
Reaction(KEGG)
Substrate
L-3,5,3'-triiodothyronine [CPD:C02465];
2-oxoglutarate [CPD:C00026]
Product
3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-2-oxopropanoate [CPD:C03832];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein. Acts on monoiodotyrosine, diiodotyrosine, triiodothyronine, thyroxine and dinitrotyrosine (unlike EC 2.6.1.24 diiodotyrosine transaminase, which does not act on dinitrotyrosine). Pyruvate or oxaloacetate can act as acceptors.
History
EC 2.6.1.26 created 1972
Reference
1  [PMID:4686924]
  Authors
Soffer RL, Hechtman P, Savage M.
  Title
L-Triiodothyronine aminotransferase.
  Journal
J. Biol. Chem. 248 (1973) 1224-30.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
51004-29-6

DBGET integrated database retrieval system