| Entry |
|
|---|
| Name |
2-aminoethylphosphonate---pyruvate transaminase;
(2-aminoethyl)phosphonate transaminase;
(2-aminoethyl)phosphonate aminotransferase;
(2-aminoethyl)phosphonic acid aminotransferase;
2-aminoethylphosphonate-pyruvate aminotransferase;
2-aminoethylphosphonate aminotransferase;
2-aminoethylphosphonate transaminase;
AEP transaminase;
AEPT |
|---|
| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
 |
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| Sysname |
(2-aminoethyl)phosphonate:pyruvate aminotransferase |
|---|
| Reaction(IUBMB) |
(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde +
L-alanine [RN:R04152] |
|---|
| Reaction(KEGG) |
R04152
 |
|---|
| Substrate |
(2-aminoethyl)phosphonate [CPD:C03557];
pyruvate [CPD:C00022] |
|---|
| Product |
2-phosphonoacetaldehyde [CPD:C03167];
L-alanine [CPD:C00041] |
|---|
| Cofactor |
Pyridoxal phosphate [CPD:C00018] |
|---|
| Comment |
A pyridoxal-phosphate protein. 2-Aminoethylarsonate can replace
2-aminoethylphosphonate as a substrate. |
|---|
| Pathway |
PATH: ec00440 Phosphonate and phosphinate metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K03430 2-aminoethylphosphonate-pyruvate transaminase |
|---|
| Genes |
STY: STY0470(phnW)
STT: t2432(phnW)
SPT: SPA2292(phnW)
SEK: SSPA2134
SPQ: SPAB_03152
SEI: SPC_0443(phnW)
SEC: SC0472(phnW)
SEH: SeHA_C0533(phnW)
SEE: SNSL254_A0478(phnW)
SEW: SeSA_A0491(phnW)
SEA: SeAg_B0470(phnW)
SED: SeD_A0472(phnW)
SEG: SG0442(phnW)
SET: SEN0413(phnW)
STM: STM0431(phnW)
KPN: KPN_04063(phnW)
KPU: KP1_5436(phnW)
HDE: HDEF_0201
XOO: XOO1391
XOM: XOO_1279
VCH: VCA0604
VCO: VC0395_0546(phnW)
VCM: VCM66_A0562(phnW)
VCJ: VCD_000715
VVU: VV2_1664
VVY: VVA0476
VPA: VPA0235
VHA: VIBHAR_04876
VSP: VS_II0398
VEX: VEA_000767
VSA: VSAL_II0812
PAE: PA1310(phnW)
PAU: PA14_47300(phnW)
PAP: PSPA7_4081(phnW)
PAG: PLES_38721(phnW)
PPU: PP_2209(phnW)
PPF: Pput_3529
PPG: PputGB1_1834
PPW: PputW619_3461
PFL: PFL_3965(phnW)
PFO: Pfl01_3683
PFS: PFLU3911
PEN: PSEEN3553(phnW)
ACB: A1S_1364
ABY: ABAYE2318(phnW)
ABC: ACICU_01380
ABN: AB57_1572(phnW)
ABB: ABBFA_002147(phnW)
SDN: Sden_1165
PIN: Ping_2747
NOC: Noc_1315
HCH: HCH_03085
AHA: AHA_1938(phnW)
REU: Reut_B3718 Reut_B5871
REH: H16_B1953
RME: Rmet_1810
CTI: RALTA_B1654
BMA: BMAA0852 BMAA1770(phnW)
BMV: BMASAVP1_0760(phnW) BMASAVP1_1756
BML: BMA10229_1053(phnW) BMA10229_2210
BMN: BMA10247_A0895 BMA10247_A2028(phnW)
BPS: BPSS0343 BPSS0507
BPM: BURPS1710b_A1899(phnW) BURPS1710b_A2063(phnW)
BPL: BURPS1106A_A0485(phnW) BURPS1106A_A0689(phnW)
BPD: BURPS668_A0582(phnW) BURPS668_A0778(phnW)
BTE: BTH_II1910 BTH_II2055(phnW)
BVI: Bcep1808_3549 Bcep1808_4685
BUR: Bcep18194_A6497 Bcep18194_B0347
BCN: Bcen_3066
BCH: Bcen2424_5301
BCM: Bcenmc03_3162 Bcenmc03_3400 Bcenmc03_4967
BCJ: BCAL0446 BCAM1243 BCAM2499
BAM: Bamb_4662
BAC: BamMC406_4014 BamMC406_5190
BMU: Bmul_3138 Bmul_3422 Bmul_4473
BMJ: BMULJ_00091(phnW) BMULJ_04037 BMULJ_05106(phnW)
BXE: Bxe_B1876
BPH: Bphy_3820 Bphy_5064 Bphy_7778
BPY: Bphyt_2142 Bphyt_5997
BGL: bglu_2g03890 bglu_2g13480
POL: Bpro_3216 Bpro_4697
VEI: Veis_0967
SCL: sce4777(phnW)
SFU: Sfum_2895
SME: SM_b21537
SMD: Smed_4874
ARA: Arad_7867(phnW)
BJA: blr2077
BAN: BA1341
BAR: GBAA1341
BAA: BA_1866
BAT: BAS1240
BAH: BAMEG_3255
BAI: BAA_1408
BCE: BC1327
BCA: BCE_1440
BCZ: BCZK1218(phnW)
BCR: BCAH187_A1481
BCB: BCB4264_A1378
BCU: BCAH820_1415
BCG: BCG9842_B3966
BCQ: BCQ_1399(phnW)
BCX: BCA_1379
BCY: Bcer98_1052
BTK: BT9727_1216(phnW)
BTL: BALH_1190(phnW)
BWE: BcerKBAB4_1241
GYM: GYMC10_0243
SCA: Sca_0878
LSP: Bsph_1360
BBE: BBR47_44970(phnW)
PJD: Pjdr2_4350
LPL: lp_0710(phnW)
LPJ: JDM1_0586(phnW)
CBL: CLK_1504
CBE: Cbei_4336
ELE: Elen_2312
BFR: BF3695
BFS: BF3487
BVU: BVU_3006
PDI: BDI_2851
STR: Sterm_3422
 |
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| Structures |
PDB: 1M32 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4982500]
La Nauze JM, Rosenberg H.
The identification of 2-phosphonoacetaldehyde as an intermediate in
the degradation of 2-aminoethylphosphonate by Bacillus cereus.
Biochim. Biophys. Acta. 165 (1968) 438-47.
Bacillus cereus |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6406228]
Dumora C, Lacoste AM, Cassaigne A.
Purification and properties of 2-aminoethylphosphonate:pyruvate
aminotransferase from Pseudomonas aeruginosa.
Eur. J. Biochem. 133 (1983) 119-25.
Pseudomonas aeruginosa |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:8394813]
Lacoste AM, Dumora C, Balas L, Hammerschmidt F, Vercauteren J.
Stereochemistry of the reaction catalysed by 2-aminoethylphosphonate
aminotransferase. A 1H-NMR study.
Eur. J. Biochem. 215 (1993) 841-4.
Pseudomonas aeruginosa |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:1527499]
Lacoste AM, Dumora C, Ali BR, Neuzil E, Dixon HB.
Utilization of 2-aminoethylarsonic acid in Pseudomonas aeruginosa.
J. Gen. Microbiol. 138 (1992) 1283-7.
Pseudomonas aeruginosa |
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| Other DBs |
ExplorEnz - The Enzyme Database: 2.6.1.37
IUBMB Enzyme Nomenclature: 2.6.1.37
ExPASy - ENZYME nomenclature database: 2.6.1.37
BRENDA, the Enzyme Database: 2.6.1.37
CAS: 37277-91-1 |
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