KEGG   ENZYME: 2.6.1.43Help
Entry
EC 2.6.1.43                 Enzyme                                 

Name
aminolevulinate transaminase;
aminolevulinate aminotransferase, gamma,delta-dioxovalerate aminotransferase;
gamma,delta-dioxovaleric acid transaminase;
4,5-dioxovalerate aminotransferase;
4,5-dioxovaleric acid transaminase;
4,5-dioxovaleric transaminase;
5-aminolevulinic acid transaminase;
alanine-gamma,delta-dioxovalerate aminotransferase;
alanine-dioxovalerate aminotransferase;
alanine:4,5-dioxovalerate aminotransferase;
aminolevulinic acid transaminase;
dioxovalerate transaminase;
L-alanine-4,5-dioxovalerate aminotransferase;
L-alanine:4,5-dioxovaleric acid transaminase;
L-alanine:dioxovalerate transaminase;
DOVA transaminase;
4,5-dioxovaleric acid aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
5-aminolevulinate:pyruvate aminotransferase
Reaction(IUBMB)
5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine [RN:R02271]
Reaction(KEGG)
Substrate
5-aminolevulinate [CPD:C00430];
pyruvate [CPD:C00022]
Product
4,5-dioxopentanoate [CPD:C02800];
L-alanine [CPD:C00041]
Comment
A pyridoxal-phosphate protein.
History
EC 2.6.1.43 created 1972
Pathway
Porphyrin and chlorophyll metabolism
Reference
1  [PMID:13898421]
  Authors
GIBSON KD, MATTHEW M, NEUBERGER A, TAIT GH.
  Title
Biosynthesis of porphyrins and chlorophylls.
  Journal
Nature. 192 (1961) 204-8.
Reference
2  [PMID:13938132]
  Authors
NEUBERGER A, TURNER JM.
  Title
gamma,delta-Dioxovalerate aminotransferase activity in Rhodopseudomonas spheroides.
  Journal
Biochim. Biophys. Acta. 67 (1963) 342-5.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9012-46-8

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