KEGG   ENZYME: 2.6.1.66Help
Entry
EC 2.6.1.66                 Enzyme                                 
Name valine---pyruvate transaminase;
transaminase C;
valine-pyruvate aminotransferase;
alanine-oxoisovalerate aminotransferase
Class Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname L-valine:pyruvate aminotransferase
Reaction(IUBMB) L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine
[RN:R01215]
Reaction(KEGG) R01215
Show
Substrate L-valine [CPD:C00183];
pyruvate [CPD:C00022]
Product 3-methyl-2-oxobutanoate [CPD:C00141];
L-alanine [CPD:C00041]
Comment Different from EC 2.6.1.42, branched-chain-amino-acid-transaminase.
Pathway PATH: ec00290  Valine, leucine and isoleucine biosynthesis
PATH: ec01100  Metabolic pathways
Orthology KO: K00835  valine--pyruvate aminotransferase
Genes CME: CML079C
DHA: DEHA0A08206g
PIC: PICST_28702(ARO9.2) PICST_89470(YEY2)
CGR: CAGL0I06578g
ECO: b3572(avtA)
ECJ: JW5652(avtA)
ECD: ECDH10B_3753(avtA)
EBW: BWG_3262(avtA)
ECE: Z4997(avtA)
ECS: ECs4455(avtA)
ECF: ECH74115_4948(avtA)
ETW: ECSP_4568(avtA)
ECG: E2348C_3824(avtA)
ECC: c4393(avtA)
ECI: UTI89_C4114(avtA)
ECP: ECP_3676(avtA)
ECV: APECO1_2878(avtA)
ECW: EcE24377A_4069(avtA)
ECX: EcHS_A3775(avtA)
ECM: EcSMS35_3895(avtA)
ECY: ECSE_3848(avtA)
ECL: EcolC_0142(avtA)
ECK: EC55989_4029(avtA)
ECQ: ECED1_4260(avtA)
ECR: ECIAI1_3739(avtA)
ECT: ECIAI39_4084(avtA)
ECZ: ECS88_3991(avtA)
EUM: ECUMN_4085(avtA)
ELF: LF82_0200(avtA)
EBL: B21_03375(avtA)
EBD: ECBD_0162
EBR: ECB_03424(avtA)
EOH: ECO103_4662(avtA)
EFE: EFER_3570(avtA)
STY: STY4133(avtA)
STT: t3854(avtA)
SPT: SPA3516(avtA)
SEK: SSPA3283(avtA)
SPQ: SPAB_04555(avtA)
SEI: SPC_3745(avtA)
SEH: SeHA_C3988(avtA)
SEE: SNSL254_A3943(avtA)
SEW: SeSA_A3863(avtA)
SEA: SeAg_B3879(avtA)
SED: SeD_A4049(avtA)
SEG: SG3766(avtA)
SET: SEN3487(avtA)
SES: SARI_03971(avtA)
STM: STM3665(avtA)
YPE: YPO4082(avtA)
YPK: y4099(avtA)
YPM: YP_3991(avtA)
YPA: YPA_3003(avtA)
YPN: YPN_3726(avtA)
YPG: YpAngola_A3792(avtA)
YPP: YPDSF_0015(avtA)
YPS: YPTB3907(avtA)
YPI: YpsIP31758_4140(avtA)
YPY: YPK_0014(avtA)
YPB: YPTS_4124(avtA)
YEN: YE4161(avtA)
SFL: SF3616(avtA)
SFX: S4153(avtA)
SFV: SFV_3968(avtA)
SBO: SBO_3580(avtA)
SBC: SbBS512_E3950(avtA)
SDY: SDY_3707(avtA)
ECA: ECA4386(avtA)
PCT: PC1_0055
ETA: ETA_34430(avtA)
PLU: plu0291(avtA)
PAY: PAU_00225(avtA)
SGL: SG0009(avtA)
ENT: Ent638_0149(avtA)
ESA: ESA_04155(avtA)
KPN: KPN_03936(avtA)
KPE: KPK_0169(avtA)
KPU: KP1_5284(avtA)
CKO: CKO_05030(avtA)
SPE: Spro_0053(avtA)
PMR: PMI2852(avtA)
EIC: NT01EI_0012
ETR: ETAE_0010(avtA)
DDA: Dd703_0050
DZE: Dd1591_0035
XCC: XCC1838(avtA)
XCB: XC_2351
XCV: XCV1904
XAC: XAC1858(avtA)
XOO: XOO2895(avtA)
XOM: XOO_2745
VCH: VC0019(avtA)
VCO: VC0395_A2500(avtA)
VCM: VCM66_0019(avtA)
VCJ: VCD_001487
VVU: VV1_0992(avtA)
VVY: VV0018(avtA)
VPA: VP0019(avtA)
VHA: VIBHAR_00447(avtA)
VSP: VS_0015(avtA)
VFI: VF_0014(avtA)
VFM: VFMJ11_0014(avtA)
VSA: VSAL_I2963(avtA)
PPR: PBPRA0054(avtA)
PCR: Pcryo_2440(avtA)
PRW: PsycPRwf_0089(avtA)
SSE: Ssed_1586(avtA)
SPL: Spea_2635(avtA)
SHL: Shal_2705(avtA)
SWD: Swoo_3063(avtA)
SWP: swp_3184(avtA)
PHA: PSHAa1703(avtA)
SDE: Sde_0903(avtA)
MAQ: Maqu_0943(avtA)
PIN: Ping_3725(avtA)
HCH: HCH_01903(avtA)
AHA: AHA_0009(avtA)
ASA: ASA_0012(avtA)
TAU: Tola_0007
NMA: NMA0636(avtA)
NME: NMB1823(avtA)
NMC: NMC0395(avtA)
NGO: NGO0082(avtA)
BPM: BURPS1710b_A0496
BLI: BL00232(avtA)
BLD: BLi04237(avtA)
SEN: SACE_4564(avtA)
LIL: LA0171(avtA)
LIC: LIC10150(avtA)
AMU: Amuc_1487(avtA)
SYC: syc1840_c(avtA)
SYF: Synpcc7942_2258(avtA)
SYP: SYNPCC7002_A0235(avtA)
TEL: tll1742(avtA)
ANA: alr2811(avtA)
TER: Tery_3688(avtA)
CPH: Cpha266_1972
DGE: Dgeo_2084
Taxonomy
Structures PDB: 3G7Q  
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:396446]
Falkinham JO 3rd.
Identification of a mutation affecting an
alanine-alpha-ketoisovalerate transaminase activity in Escherichia
coli K-12.
Mol. Gen. Genet. 176 (1979) 147-9.
Escherichia coli [GN:eco]
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:13034817]
RUDMAN D, MEISTER A.
Transamination in Escherichia coli.
J. Biol. Chem. 200 (1953) 591-604.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 2.6.1.66
IUBMB Enzyme Nomenclature: 2.6.1.66
ExPASy - ENZYME nomenclature database: 2.6.1.66
BRENDA, the Enzyme Database: 2.6.1.66
CAS: 73379-50-7
DBGET integrated database retrieval system