| Entry |
|
|---|
| Name |
putrescine aminotransferase;
putrescine-alpha-ketoglutarate transaminase;
YgjG;
putrescine:alpha-ketoglutarate aminotransferase;
PAT;
putrescine:2-oxoglutarate aminotransferase;
putrescine transaminase |
|---|
| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
 |
|---|
| Sysname |
butane-1,4-diamine:2-oxoglutarate aminotransferase |
|---|
| Reaction(IUBMB) |
(1) (1a) putrescine + 2-oxoglutarate = 4-aminobutanal + L-glutamate
[RN:R01155];
(2) (1b) 4-aminobutanal = 1-pyrroline (spontaneous) [RN:R07408] |
|---|
| Reaction(KEGG) |
R01155 R07408
 |
|---|
| Substrate |
putrescine [CPD:C00134];
2-oxoglutarate [CPD:C00026];
4-aminobutanal [CPD:C00555] |
|---|
| Product |
4-aminobutanal [CPD:C00555];
L-glutamate [CPD:C00025];
1-pyrroline [CPD:C15668] |
|---|
| Comment |
A pyridoxal-phosphate protein [3]. The product, 4-aminobutanal,
spontaneously cyclizes to form 1-pyrroline, which is a substrate for
EC 1.2.1.19, aminobutyraldehyde dehydrogenase. Cadaverine and
spermidine can also act as substrates [3]. Forms part of the
arginine-catabolism pathway [2]. |
|---|
| Pathway |
PATH: ec00330 Arginine and proline metabolism |
|---|
| Orthology |
KO: K09251 putrescine aminotransferase |
|---|
| Genes |
ECO: b3073(patA)
ECJ: JW5510(ygjG)
ECD: ECDH10B_3248(ygjG)
EBW: BWG_2783(ygjG)
ECE: Z4426(ygjG)
ECS: ECs3955
ECF: ECH74115_4387(ygjG)
ETW: ECSP_4047(ygjG)
ECG: E2348C_3366(ygjG)
ECC: c3828(ygjG)
ECI: UTI89_C3511(ygjG)
ECP: ECP_3163
ECV: APECO1_3343(ygjG)
ECW: EcE24377A_3540(rocD)
ECX: EcHS_A3255(ygjG)
ECM: EcSMS35_3367(ygjG)
ECY: ECSE_3354
ECL: EcolC_0627
ECK: EC55989_3487(ygjG)
ECQ: ECED1_3741(ygjG)
ECR: ECIAI1_3220(ygjG)
ECT: ECIAI39_3571(ygjG)
ECZ: ECS88_3470(ygjG)
EUM: ECUMN_3556(ygjG)
ELF: LF82_3225(ygjG)
EBL: B21_02892(ygjG)
EBD: ECBD_0669
EBR: ECB_02942(ygjG)
EOH: ECO103_3818(ygjG)
EOI: ECO111_3895(ygjG)
EOJ: ECO26_4174(ygjG)
EFE: EFER_3025(ygjG)
STY: STY3396
STT: t3138
SPT: SPA3086(oat)
SEK: SSPA2882
SPQ: SPAB_04016
SEI: SPC_3294(oat)
SEC: SC3165(oat)
SEH: SeHA_C3513(ygjG)
SEE: SNSL254_A3479(ygjG)
SEW: SeSA_A3409(ygjG)
SEA: SeAg_B3405(ygjG)
SED: SeD_A3575(rocD)
SEG: SG3114(oat)
SET: SEN3060(oat)
SES: SARI_04409
STM: STM3218(oat)
SFL: SF3114(ygjG)
SFX: S3320(ygjG)
SFV: SFV_3114(ygjG)
SSN: SSON_3211(ygjG)
SBO: SBO_2932(ygjG)
ECA: ECA1543
PCT: PC1_1416
PWA: Pecwa_1819
ENT: Ent638_3528
ESA: ESA_03492
CTU: Ctu_04740(patA)
KPN: KPN_03501(ygjG)
KPE: KPK_0611(ygjG)
KPU: KP1_4798(ygjG)
CKO: CKO_04486
DDA: Dd703_1304 Dd703_3241
DDC: Dd586_2605
DZE: Dd1591_2699
DBA: Dbac_2006
DOL: Dole_1070
BWE: BcerKBAB4_1277
LLK: LLKF_1589
CBE: Cbei_4934
AMT: Amet_4317
AOE: Clos_2419
DAE: Dtox_1194
DAU: Daud_0653
HMO: HM1_1941(oat)
TEX: Teth514_0819
TPD: Teth39_0327
ADG: Adeg_1419
CPO: COPRO5265_0652
NTH: Nther_0106
HOR: Hore_17220
FRE: Franean1_5761
NML: Namu_5127
AMI: Amir_3615
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3510672]
Prieto-Santos MI, Martin-Checa J, Balana-Fouce R, Garrido-Pertierra
A.
A pathway for putrescine catabolism in Escherichia coli.
Biochim. Biophys. Acta. 880 (1986) 242-4.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:16023116]
Samsonova NN, Smirnov SV, Novikova AE, Ptitsyn LR.
Identification of Escherichia coli K12 YdcW protein as a
gamma-aminobutyraldehyde dehydrogenase.
FEBS. Lett. 579 (2005) 4107-12.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:12617754]
Samsonova NN, Smirnov SV, Altman IB, Ptitsyn LR.
Molecular cloning and characterization of Escherichia coli K12 ygjG
gene.
BMC. Microbiol. 3 (2003) 2.
Escherichia coli [GN:eco] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.6.1.82
IUBMB Enzyme Nomenclature: 2.6.1.82
ExPASy - ENZYME nomenclature database: 2.6.1.82
BRENDA, the Enzyme Database: 2.6.1.82
CAS: 98982-73-1 |
|---|
