| Entry |
|
|---|
| Name |
inositol-tetrakisphosphate 5-kinase;
1D-myo-inositol-tetrakisphosphate 5-kinase |
|---|
| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
 |
|---|
| Sysname |
ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase |
|---|
| Reaction(IUBMB) |
ATP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate = ADP +
1D-myo-inositol 1,3,4,5,6-pentakisphosphate [RN:R03478] |
|---|
| Reaction(KEGG) |
R03478
 |
|---|
| Substrate |
ATP [CPD:C00002];
1D-myo-inositol 1,3,4,6-tetrakisphosphate [CPD:C04477] |
|---|
| Product |
ADP [CPD:C00008];
1D-myo-inositol 1,3,4,5,6-pentakisphosphate [CPD:C01284] |
|---|
| Comment |
The enzyme from plants and yeast can also use Ins(1,2,3,4,6)P5 as a
substrate [2]. |
|---|
| Pathway |
PATH: ec00562 Inositol phosphate metabolism
PATH: ec01100 Metabolic pathways
PATH: ec04070 Phosphatidylinositol signaling system |
|---|
| Orthology |
KO: K00915 1D-myo-Inositol-tetrakisphosphate 5-kinase |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:2584198]
Shears SB.
The pathway of myo-inositol 1,3,4-trisphosphate phosphorylation in
liver. Identification of myo-inositol 1,3,4-trisphosphate 6-kinase,
myo-inositol 1,3,4-trisphosphate 5-kinase, and myo-inositol
1,3,4,6-tetrakisphosphate 5-kinase.
J. Biol. Chem. 264 (1989) 19879-86.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:12226109]
Stevenson-Paulik J, Odom AR, York JD.
Molecular and biochemical characterization of two plant inositol
polyphosphate 6-/3-/5-kinases.
J. Biol. Chem. 277 (2002) 42711-8.
Arabidopsis thaliana [GN:ath] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.7.1.140
IUBMB Enzyme Nomenclature: 2.7.1.140
ExPASy - ENZYME nomenclature database: 2.7.1.140
BRENDA, the Enzyme Database: 2.7.1.140
CAS: 123940-40-9 |
|---|
|
