KEGG   ENZYME: 2.7.1.20Help
Entry
EC 2.7.1.20                 Enzyme                                 
Name adenosine kinase;
adenosine kinase (phosphorylating)
Class Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname ATP:adenosine 5'-phosphotransferase
Reaction(IUBMB) ATP + adenosine = ADP + AMP [RN:R00185]
Reaction(KEGG) R00185
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Substrate ATP [CPD:C00002];
adenosine [CPD:C00212]
Product ADP [CPD:C00008];
AMP [CPD:C00020]
Comment 2-Aminoadenosine can also act as acceptor.
Pathway PATH: ec00230  Purine metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K00856  adenosine kinase
Genes HSA: 132(ADK)
PTR: 450902(ADK)
MCC: 705246(ADK)
MMU: 11534(Adk)
RNO: 25368(Adk)
CFA: 479253(ADK)
BTA: 783572(ADK)
SSC: 100154626
ECB: 100072901(ADK)
MDO: 100011774
GGA: 423735(ADK)
TGU: 100230888
XLA: 444786
XTR: 549452(adk)
DRE: 322229(adkb) 368220(adka)
BFO: BRAFLDRAFT_107090
CIN: 100175447
SPU: 580959
DME: Dmel_CG11255 Dmel_CG1851(Ady43A) Dmel_CG3809
DPO: Dpse_GA14968 Dpse_GA17700 Dpse_GA23538
DAN: Dana_GF12238 Dana_GF17233 Dana_GF25174
DER: Dere_GG10762 Dere_GG13787 Dere_GG18640
DPE: Dper_GL10944 Dper_GL22267 Dper_GL24870
DSE: Dsec_GM20810 Dsec_GM24000 Dsec_GM24613
DSI: Dsim_GD10267 Dsim_GD12680 Dsim_GD18802
DYA: Dyak_GE20080 Dyak_GE24147 Dyak_GE26161
DGR: Dgri_GH15477 Dgri_GH20370 Dgri_GH23323
DMO: Dmoj_GI10274 Dmoj_GI13634 Dmoj_GI20045
AGA: AgaP_AGAP010137
AAG: AaeL_AAEL001102 AaeL_AAEL001856
CQU: CpipJ_CPIJ000509 CpipJ_CPIJ005720
AME: 408441 551856
NVI: 100114054 100116821
TCA: 657611 659475
API: 100167522
ISC: IscW_ISCW021148
CEL: R07H5.8
CBR: CBG06032
BMY: Bm1_08850
SMM: Smp_008360 Smp_008400
NVE: NEMVE_v1g163941
HMG: 100204434
TAD: TRIADDRAFT_50549
ATH: AT3G09820(ADK1) AT5G03300(ADK2)
POP: POPTR_659896 POPTR_720292
RCU: RCOM_0262240
VVI: 100241094(GSVIVT00018174001) 100246211(GSVIVT00018170001)
OSA: 4330032(Os02g0625500) 4336412(Os04g0518000)
SBI: SORBI_06g022730(SORBIDRAFT_06g022730)
PPP: PHYPADRAFT_184505
CRE: CHLREDRAFT_190547(FAP278)
OLU: OSTLU_50659
CME: CMK016C
SCE: YJR105W(ADO1)
AGO: AGOS_ABR161C
KLA: KLLA0D10890g
LTH: KLTH0E01342g
DHA: DEHA0B07139g
PIC: PICST_57331(ADO1)
PPA: PAS_chr2-2_0162
VPO: Kpol_1013p60
LEL: LELG_04989
ZRO: ZYRO0D01936g
CAL: CaO19.5591
CTP: CTRG_05407
CDU: CD36_63990
CGR: CAGL0C04983g
YLI: YALI0F23463g
SPO: SPCC338.14
NCR: NCU00414
PAN: PODANSg5217
MGR: MGG_06270
FGR: FG06932.1
ANI: AN2272.2
AFM: AFUA_5G06390
AOR: AO090009000617
ANG: An17g01330
AFV: AFLA_048840
PCS: Pc21g17460
NFI: NFIA_036740
CIM: CIMG_06031
URE: UREG_04340
SSL: SS1G_00597
BFU: BC1G_06571
CNE: CNN02130
CNB: CNBN2170
LBC: LACBIDRAFT_192435
MPR: MPER_12242
UMA: UM00797.1
MGL: MGL_0728
MBR: MONBRDRAFT_39088
DDI: DDB_0230174
CPV: cgd8_2370
TGO: TGME49_050880
PTM: GSPATT00023892001 GSPATT00034523001
TBR: Tb927.6.2300 Tb927.6.2360
TCR: 509051.40 509965.370
LMA: LmjF30.0880 LmjF30.0890 LmjF34.3600
LIF: LinJ30.1250 LinJ34.3120
LBZ: LbrM20_V2.3180 LbrM30_V2.1010
PTI: PHATRDRAFT_51242
TPS: THAPSDRAFT_644(AK2)
XCC: XCC3471
XCB: XC_0690
XCA: xccb100_0723
XCV: XCV0716
XAC: XAC0655
XOO: XOO3971
XOM: XOO_3749
XOP: PXO_04263
SML: Smlt4060
SMT: Smal_3455
MCA: MCA0047
NOC: Noc_2548
HHA: Hhal_1195
TGR: Tgr7_0173
AFE: Lferr_0688
AFR: AFE_0530
RMA: Rmag_1022
VOK: COSY_0923
LHK: LHK_03084(pfkB)
RSO: RSc2791
RPI: Rpic_3036
RPF: Rpic12D_2626
REU: Reut_A2870
REH: H16_A3176
RME: Rmet_3069
CTI: RALTA_A2651
BMA: BMA2506
BMV: BMASAVP1_A0427
BML: BMA10229_A1286
BMN: BMA10247_3278
BPS: BPSL2988
BPM: BURPS1710b_3506(pfkB)
BPL: BURPS1106A_3508
BPD: BURPS668_3470
BPR: GBP346_A3653
BTE: BTH_I1158
BVI: Bcep1808_0575
BUR: Bcep18194_A3683
BCN: Bcen_0117
BCH: Bcen2424_0600
BCM: Bcenmc03_0569
BCJ: BCAL3425
BAM: Bamb_0502
BAC: BamMC406_0526
BMU: Bmul_2784
BMJ: BMULJ_00453(adk)
BXE: Bxe_A0527
BPH: Bphy_2634
BPY: Bphyt_3431
BGL: bglu_1g05020
PNU: Pnuc_0207
PNE: Pnec_0225
BPE: BP2993
BPA: BPP3913
BBR: BB4386
BPT: Bpet0578
BAV: BAV2993(adoK)
POL: Bpro_1103
PNA: Pnap_3388
AAV: Aave_0861
AJS: Ajs_3635
VEI: Veis_1493
DAC: Daci_1498
DIA: Dtpsy_2945
VAP: Vapar_0953
CTT: CtCNB1_4085
MPT: Mpe_A3210
HAR: HEAR2766(adoK)
MMS: mma_2975(pfkB)
LCH: Lcho_0386
NEU: NE0611
NET: Neut_1951
NMU: Nmul_A0209
EBA: ebA1485(pfkB)
AZO: azo0857
DAR: Daro_3935
TBD: Tbd_0171
MFA: Mfla_0471
MMB: Mmol_0491
MEI: Msip34_2268
APP: CAP2UW1_4139
DVU: DVU0988
DVL: Dvul_2001
DVM: DvMF_2935
DDE: Dde_1489
DDS: Ddes_0200
DMA: DMR_18910
DSA: Desal_2501
LIP: LI0780(fruK)
SFU: Sfum_0800
BRA: BRADO0031
BBT: BBta_0036
CCE: Ccel_1080
MTU: Rv2202c(cbhK)
MTC: MT2258
MRA: MRA_2218(cbhK)
MTF: TBFG_12230
MTB: TBMG_01779(TBMG_01779.1)
MBO: Mb2225c(cbhK)
MBB: BCG_2218c(adoK)
MBT: JTY_2212(adoK)
MLE: ML0873
MLB: MLBr_00873
MPA: MAP1942c(cbhK)
MAV: MAV_2289
MSM: MSMEG_4270
MUL: MUL_3559(cbhK)
MVA: Mvan_3566
MGI: Mflv_2947
MAB: MAB_1959
MMC: Mmcs_3300
MKM: Mkms_3362
MJL: Mjls_3311
MMI: MMAR_3246(cbhK)
NFA: nfa17060
RHA: RHA1_ro01139
RER: RER_36040(adoK)
ROP: ROP_08670(adoK)
GBR: Gbro_3063
SCO: SCO2158(SC6G10.31c)
SMA: SAV_6045
SGR: SGR_5350
NCA: Noca_3144
TFU: Tfu_1012
TCU: Tcur_3081
SRO: Sros_2666
FRA: Francci3_3120
FRE: Franean1_1798
FAL: FRAAL5126(adoK)
ACE: Acel_0955
NML: Namu_3257
SEN: SACE_1656(adoK) SACE_3899(adoK)
SVI: Svir_27030
STP: Strop_3303
SAQ: Sare_3535
CAI: Caci_1665
RBI: RB2501_14094
CCH: Cag_1382
RRS: RoseRS_0487
RCA: Rcas_0158
CAU: Caur_3023
CAG: Cagg_3562
CHL: Chy400_3269
HAU: Haur_2351
Taxonomy
Structures PDB: 1BX4  1DGM  1LII  1LIJ  1LIK  1LIO  2A9Y  2A9Z  2AA0  2AB8  
     2ABS  2GL0  2PKF  2PKK  2PKM  2PKN  
Reference
  Authors
  Title
  Journal
  Organism
 1  [PMID:4290214]
Lindberg B, Klenow H, Hansen K.
Some properties of partially purified mammalian adenosine kinase.
J. Biol. Chem. 242 (1967) 350-6.
Oryctolagus cuniculus
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:14832298]
CAPUTTO R.
The enzymatic synthesis of adenylic acid; adenosinekinase.
J. Biol. Chem. 189 (1951) 801-14.
Saccharomyces cerevisiae [GN:sce]
Reference
  Authors
  Title

  Journal
  Organism
 3  [PMID:14907737]
KORNBERG A, PRICER WE Jr.
Enzymatic phosphorylation of adenosine and 2,6-diaminopurine
riboside.
J. Biol. Chem. 193 (1951) 481-95.
Saccharomyces cerevisiae [GN:sce]
Other DBs ExplorEnz - The Enzyme Database: 2.7.1.20
IUBMB Enzyme Nomenclature: 2.7.1.20
ExPASy - ENZYME nomenclature database: 2.7.1.20
BRENDA, the Enzyme Database: 2.7.1.20
CAS: 9027-72-9
DBGET integrated database retrieval system