KEGG   ENZYME: 2.7.1.3Help
Entry
EC 2.7.1.3                  Enzyme                                 

Name
ketohexokinase;
ketohexokinase (phosphorylating)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:D-fructose 1-phosphotransferase
Reaction(IUBMB)
ATP + D-fructose = ADP + D-fructose 1-phosphate [RN:R00866]
Reaction(KEGG)
R00866;
(other) R03819
Show
Substrate
ATP [CPD:C00002];
D-fructose [CPD:C00095]
Product
ADP [CPD:C00008];
D-fructose 1-phosphate [CPD:C01094]
Comment
D-Sorbose, D-tagatose and 5-dehydro-D-fructose and a number of other ketoses and their analogues can also act as substrates [4].
History
EC 2.7.1.3 created 1961
Pathway
Fructose and mannose metabolism
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K00846  
ketohexokinase
Genes
HSA: 
3795(KHK)
PTR: 
740614(KHK)
PPS: 
GGO: 
PON: 
MCC: 
698328(KHK)
MCF: 
MMU: 
16548(Khk)
RNO: 
25659(Khk)
CGE: 
HGL: 
TUP: 
CFA: 
AML: 
FCA: 
PTG: 
BTA: 
614868(KHK)
BOM: 
PHD: 
CHX: 
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
OAA: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
CMY: 
ACS: 
PBI: 
XLA: 
447317(khk)
XTR: 
DRE: 
436909(khk)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
726522(GB14491)
NVI: 
LOA: 
NVE: 
HMG: 
TAD: 
AQU: 
SLY: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
FGR: 
NHE: 
TRE: 
MAW: 
CMT: 
VAL: 
AOR: 
AOR_1_1534174(AO090005000876)
ANG: 
ANI_1_774014(An01g06030)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
AJE: 
PNO: 
PTE: 
BZE: 
PFJ: 
PIF: 
EHX: 
TCY: 
MEJ: 
MEC: 
NOC: 
NHL: 
NWA: 
TVI: 
TMB: 
HHA: 
TGR: 
TKM: 
TNI: 
TVNIR_3462(ydjH_[C])
HNA: 
MOX: 
 » show all
Taxonomy
Reference
1  [PMID:14858418]
  Authors
CORI GT, OCHOA S, SLEIN MW, CORI CF.
  Title
The metabolism of fructose in liver; isolation of fructose-I-phosphate and inorganic pyrophosphate.
  Journal
Biochim. Biophys. Acta. 7 (1951) 304-17.
  Organism
Rattus norvegicus
Reference
2  [PMID:13208667]
  Authors
HERS HG.
  Title
[Liver fructokinase.]
  Journal
Biochim. Biophys. Acta. 8 (1952) 416-23.
  Organism
Bos taurus
Reference
3  [PMID:13449068]
  Authors
PARKS RE Jr, BEN-GERSHOM E, LARDY HA.
  Title
Liver fructokinase.
  Journal
J. Biol. Chem. 227 (1957) 231-42.
  Organism
Rattus norvegicus, Bos taurus
Reference
4  [PMID:193556]
  Authors
Raushel FM, Cleland WW.
  Title
Bovine liver fructokinase: purification and kinetic properties.
  Journal
Biochemistry. 16 (1977) 2169-75.
  Organism
Bos taurus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9030-50-6

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