| Entry |
|
|---|
| Name |
deoxyadenosine kinase;
purine-deoxyribonucleoside kinase |
|---|
| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
 |
|---|
| Sysname |
ATP:deoxyadenosine 5'-phosphotransferase |
|---|
| Reaction(IUBMB) |
ATP + deoxyadenosine = ADP + dAMP [RN:R02089] |
|---|
| Reaction(KEGG) |
R02089
 |
|---|
| Substrate |
ATP [CPD:C00002];
deoxyadenosine [CPD:C00559] |
|---|
| Product |
ADP [CPD:C00008];
dAMP [CPD:C00360] |
|---|
| Comment |
Deoxyguanosine can also act as acceptor. Possibly identical with EC
2.7.1.74 deoxycytidine kinase. |
|---|
| Pathway |
PATH: ec00230 Purine metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K10353 deoxyadenosine kinase |
|---|
| Genes |
BUR: Bcep18194_A3843
HAR: HEAR2640
BCZ: BCZK0015(dck)
BTL: BALH_0015(dck)
SPZ: M5005_Spy_0103
SPH: MGAS10270_Spy0105
SPI: MGAS10750_Spy0110
SPJ: MGAS2096_Spy0106
SPK: MGAS9429_Spy0104
SPF: SpyM50100
SPA: M6_Spy0152
SPB: M28_Spy0101
LDB: Ldb2196(dak)
LBU: LBUL_2017
CPF: CPF_0067
 |
|---|
| Structures |
PDB: 2JAQ |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6284353]
Chang CH, Brockman RW, Bennett LL Jr.
Purification and some properties of a deoxyribonucleoside kinase
from L1210 cells.
Cancer. Res. 42 (1982) 3033-9.
Mus musculus [GN:mmu] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:5667299]
Krygier V, Momparler RL.
The regulatory properties of deoxyadenosine kinase.
Biochim. Biophys. Acta. 161 (1968) 578-80.
Bos taurus [GN:bta] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.7.1.76
IUBMB Enzyme Nomenclature: 2.7.1.76
ExPASy - ENZYME nomenclature database: 2.7.1.76
BRENDA, the Enzyme Database: 2.7.1.76
CAS: 37278-12-9 |
|---|
