KEGG   ENZYME: 2.7.1.90Help
Entry
EC 2.7.1.90                 Enzyme                                 

Name
diphosphate---fructose-6-phosphate 1-phosphotransferase;
6-phosphofructokinase (pyrophosphate);
pyrophosphate-fructose 6-phosphate 1-phosphotransferase;
inorganic pyrophosphate-dependent phosphofructokinase;
inorganic pyrophosphate-phosphofructokinase;
pyrophosphate-dependent phosphofructo-1-kinase;
pyrophosphate-fructose 6-phosphate phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
diphosphate:D-fructose-6-phosphate 1-phosphotransferase
Reaction(IUBMB)
diphosphate + D-fructose 6-phosphate = phosphate + D-fructose 1,6-bisphosphate [RN:R00764]
Reaction(KEGG)
Substrate
diphosphate [CPD:C00013];
D-fructose 6-phosphate [CPD:C00085]
Product
phosphate [CPD:C00009];
D-fructose 1,6-bisphosphate [CPD:C00354]
Comment
The enzyme catalyses a similar reaction to EC 2.7.1.11, 6-phosphofructokinase, but utilizes diphosphate instead of ATP as the the phosphate donor. It has been described in higher plants, primitive eukaryotes, bacteria, and archaea.
History
EC 2.7.1.90 created 1976
Pathway
Fructose and mannose metabolism
Orthology
K00895  
pyrophosphate--fructose-6-phosphate 1-phosphotransferase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0002s00490g(POPTRDRAFT_550714) POPTR_0004s00550g POPTR_0005s27920g(POPTRDRAFT_761666) POPTR_0011s01970g POPTR_0011s02000g(POPTRDRAFT_1093153)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os02t0714200-01(Os02g0714200) Os06t0247500-01(Os06g0247500) Os06t0326400-01(Os06g0326400) Os08t0345700-01(Os08g0345700) Os09t0298100-00(Os09g0298100)
OBR: 
BDI: 
SBI: 
SORBI_02g020400(SORBIDRAFT_02g020400) SORBI_04g030000(SORBIDRAFT_04g030000) SORBI_07g012720(SORBIDRAFT_07g012720) SORBI_10g008850(SORBIDRAFT_10g008850)
ZMA: 
100191851 100193340(pco110217) 100280449(gpm893) 100282190(gpm74) 100382182
SITA: 
ATR: 
s00022p00121950(AMTR_s00022p00121950) s00111p00148440(AMTR_s00111p00148440) s00136p00065750(AMTR_s00136p00065750)
SMO: 
PPP: 
MIS: 
MPP: 
CSL: 
CVR: 
CME: 
GSL: 
CCP: 
EHI: 
EHI_000730(91.t00031)
EDI: 
ACAN: 
PTI: 
TPS: 
EHX: 
GLA: 
MMT: 
MAH: 
APP: 
DOL: 
DAL: 
DAT: 
DTO: 
DAO: 
SFU: 
SME: 
SMK: 
SMQ: 
SMX: 
SMI: 
SMEG: 
SMEL: 
SMD: 
RHI: 
SFH: 
SFD: 
EAD: 
ATU: 
Atu2115(pfp)
ARA: 
AVI: 
AGR: 
RET: 
REC: 
REL: 
RLE: 
RL3322(pfp)
RLT: 
RLG: 
RLB: 
RLU: 
RTR: 
RIR: 
RHL: 
NGL: 
LAS: 
LAA: 
LSO: 
LCC: 
LAR: 
lam_599(pfkA)
MET: 
MNO: 
EUC: 
BCV: 
BFA: 
JDE: 
XCE: 
IVA: 
SKE: 
CFL: 
CFI: 
CGA: 
PAC: 
PAK: 
PAV: 
PAX: 
PAZ: 
PAW: 
PAD: 
PCN: 
PACC: 
PACH: 
PFR: 
PPC: 
PBO: 
PRA: 
MPH: 
NCA: 
KFL: 
NML: 
AHE: 
MCU: 
TPY: 
ASG: 
CTR: 
CT_207(pfkA_2)
CTD: 
CTDEC_0207(pfkA_2)
CTF: 
CTDLC_0207(pfkA_2)
CTRD: 
CTRO: 
CTRT: 
CTA: 
CTA_0225(pfkA_2)
CTY: 
CTR_2011(pfkA_2)
CRA: 
CTRQ: 
CTRX: 
CTRZ: 
CTRP: 
CTLJ: 
CTLX: 
CTLL: 
CTB: 
CTL0459(pfkA_2)
CTRR: 
CTLF: 
CTLI: 
CTL: 
CTLon_0454(pfkA_2)
CTRU: 
CTRL: 
CTRV: 
CTRM: 
CTLA: 
CTLM: 
CTLS: 
CTLZ: 
CTLC: 
CTLN: 
CTLB: 
CTLQ: 
CTO: 
CTRN: 
CTJ: 
JALI_2011(pfkA_2)
CTZ: 
CTB_2011(pfkA_2)
CTG: 
CTK: 
CSW: 
SW2_2081(pfkA_2)
CES: 
ESW3_2081(pfkA_2)
CTRB: 
CTRE: 
CTRS: 
CTEC: 
EC599_2091(pfkA_2)
CFS: 
FSW4_2081(pfkA_2)
CFW: 
FSW5_2081(pfkA_2)
CTFW: 
SWFP_2171(pfkA_2)
CTRF: 
CTCH: 
CTN: 
CTQ: 
CTV: 
CTW: 
CTRG: 
CTRI: 
BN197_2061(pfkA_2)
CTRA: 
BN442_2061(pfkA_2)
CTRH: 
CTRJ: 
CTRK: 
CTJT: 
CTCF: 
CTFS: 
CTHF: 
CTCJ: 
CTHJ: 
CTMJ: 
CTTJ: 
CTJS: 
CTRC: 
CTRW: 
CTRY: 
CTCT: 
CMU: 
TC_0479(pfkA-2)
CMN: 
CPN: 
CPn0160(pfkA_1)
CPA: 
CPJ: 
CPj0160(pfkA_1)
CPT: 
CLP: 
CPM: 
CPEC: 
CPEO: 
CPER: 
CHP: 
CHB: 
CHS: 
CHI: 
CHT: 
CHC: 
CPSC: 
CPSN: 
CPSB: 
CPSG: 
CPSM: 
CPSI: 
CPSV: 
CPSW: 
CPST: 
CPSD: 
CPSA: 
CAV: 
M832_03910(pfp-BETA2)
CCA: 
CAB: 
CFE: 
CF0393(pfkA1)
PCU: 
pc0880(pfkA)
PUV: 
PUV_13700(pFP-BETA)
WCH: 
wcw_1081(pfkA)
SNG: 
SNE_A09660(pFP-BETA)
OTE: 
CAA: 
BBZ: 
BBN: 
BBJ: 
BBUR: 
BGA: 
BG0020(pfpB)
BGB: 
KK9_0020(pfpB)
BGN: 
BAF: 
BAFZ: 
BAFH: 
BBS: 
BVT: 
BTU: 
BHR: 
BDU: 
BDU_26(pfpB)
BRE: 
BRE_25(pfpB)
BCW: 
BMO: 
TPA: 
TPW: 
TPP: 
TPU: 
TPH: 
TPO: 
TPAS: 
TPC: 
TPG: 
TPM: 
TPB: 
TDE: 
TBE: 
TAZ: 
TPI: 
TPL: 
TPED: 
SCD: 
SSM: 
STA: 
STQ: 
SFC: 
SLR: 
SBU: 
SCC: 
SGP: 
FSU: 
FSC: 
EMI: 
RSD: 
RBA: 
RB10591(pfk)
BTH: 
BFR: 
BFS: 
BFG: 
BVU: 
BHL: 
BSA: 
BXY: 
PGI: 
PG0163(pfk)
PGN: 
PGT: 
PDI: 
PPN: 
TFO: 
BVS: 
APS: 
PRU: 
PMZ: 
PDN: 
PIT: 
PDT: 
PRO: 
DOI: 
 » show all
Taxonomy
Reference
1  [PMID:178659]
  Authors
Reeves RE, Serrano R, South DJ.
  Title
6-phosphofructokinase (pyrophosphate). Properties of the enzyme from Entamoeba histolytica and its reaction mechanism.
  Journal
J. Biol. Chem. 251 (1976) 2958-62.
  Sequence
[up:Q27651]
Reference
2  [PMID:4372217]
  Authors
Reeves RE, South DJ, Blytt HJ, Warren LG.
  Title
Pyrophosphate:D-fructose 6-phosphate 1-phosphotransferase. A new enzyme with the glycolytic function of 6-phosphofructokinase.
  Journal
J. Biol. Chem. 249 (1974) 7737-41.
  Sequence
[up:Q27651]
Reference
3  [PMID:2170409]
  Authors
Carlisle SM, Blakeley SD, Hemmingsen SM, Trevanion SJ, Hiyoshi T, Kruger NJ, Dennis DT
  Title
Pyrophosphate-dependent phosphofructokinase. Conservation of protein sequence between the alpha- and beta-subunits and with the ATP-dependent phosphofructokinase.
  Journal
J. Biol. Chem. 265 (1990) 18366-71.
  Sequence
Reference
4  [PMID:1653240]
  Authors
Ladror US, Gollapudi L, Tripathi RL, Latshaw SP, Kemp RG
  Title
Cloning, sequencing, and expression of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii.
  Journal
J. Biol. Chem. 266 (1991) 16550-5.
  Sequence
Reference
5  [PMID:9555897]
  Authors
Siebers B, Klenk HP, Hensel R
  Title
PPi-dependent phosphofructokinase from Thermoproteus tenax, an archaeal descendant of an ancient line in phosphofructokinase evolution.
  Journal
J. Bacteriol. 180 (1998) 2137-43.
  Sequence
[ttn:TTX_1277]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
55326-40-4

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