| Entry |
|
|---|
| Name |
creatine kinase;
ATP:creatine phosphotransferase;
CK;
MM-CK;
MB-CK;
BB-CK;
creatine phosphokinase;
creatine phosphotransferase;
phosphocreatine kinase;
adenosine triphosphate-creatine transphosphorylase;
Mi-CK;
CK-BB;
CK-MM;
CK-MB;
CKMiMi;
MiMi-CK |
|---|
| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a nitrogenous group as acceptor
 |
|---|
| Sysname |
ATP:creatine N-phosphotransferase |
|---|
| Reaction(IUBMB) |
ATP + creatine = ADP + phosphocreatine [RN:R01881] |
|---|
| Reaction(KEGG) |
R01881
 |
|---|
| Substrate |
ATP [CPD:C00002];
creatine [CPD:C00300] |
|---|
| Product |
ADP [CPD:C00008];
phosphocreatine [CPD:C02305] |
|---|
| Comment |
N-Ethylglycocyamine can also act as acceptor. |
|---|
| Pathway |
PATH: ec00330 Arginine and proline metabolism |
|---|
| Orthology |
KO: K00933 creatine kinase |
|---|
| Genes |
HSA: 1152(CKB) 1158(CKM) 1159(CKMT1B) 1160(CKMT2) 548596(CKMT1A)
PTR: 453185(CKB) 461770(CKMT2) 744935(CKM)
MCC: 711167(CKB) 711434(CKMT2) 712886
MMU: 12709(Ckb) 12715(Ckm) 12716(Ckmt1) 329504(Lcmt2) 76722(Ckmt2)
RNO: 24264(Ckb) 24265(Ckm) 29593(Ckmt1) 688698(Ckmt2)
CFA: 476435(CKM) 478277 479163(CKMT2) 480443(CKB) 482930
BTA: 281692(CKMT1) 286822(CKM) 516210(CKB) 538944(CKMT2)
SSC: 397264(CKM) 733602(CKMT2)
ECB: 100055201 100056283(CKMT1B) 100065641 100073253
MDO: 100011609 100012235 100015112 100017071
OAA: 100076820 100081308 100085972
GGA: 374002(CKMT1A) 396248(CKB) 396507 396508(CKMT2)
TGU: 100190470 100225089 100228000
XLA: 379216 379765(ckm) 380055(ckb) 380155(ckmt1)
XTR: 395000(ckmt1b) 395005(ckm) 733543(ckb)
DRE: 140744(ckbb) 30095(ckma) 321892(ckmt1) 799492(ckmt2)
BFO: BRAFLDRAFT_216834 BRAFLDRAFT_88544
CIN: 100176946 100178756 100181049
SPU: 373287(TCK) 589605 758425 762696
DPO: Dpse_GA16624
DAN: Dana_GF23510
DER: Dere_GG15040
DPE: Dper_GL15080
DSE: Dsec_GM24893
DSI: Dsim_GD14150
DYA: Dyak_GE21263
DGR: Dgri_GH15902
DMO: Dmoj_GI16555
AGA: AgaP_AGAP005627
AAG: AaeL_AAEL009185
CQU: CpipJ_CPIJ007538
AME: 550932(Argk)
NVI: 100114388
TCA: 660479
ISC: IscW_ISCW021028
CBR: CBG04174 CBG11000
BMY: Bm1_23610 Bm1_37040
NVE: NEMVE_v1g234345
HMG: 100212485
ZMA: 100273160
MBR: MONBRDRAFT_21418 MONBRDRAFT_34875
PTI: PHATRDRAFT_11733
TPS: THAPSDRAFT_263946
DPS: DP1035
 |
|---|
| Structures |
PDB: 1CRK 1G0W 1I0E 1QH4 1QK1 1U6R 1VRP 2CRK 2GL6 3B6R
3DRB 3DRE |
|---|
Reference
Authors
Title
Journal
|
1 [PMID:13235819]
ENNOR AH, ROSENBERG H, ARMSTRONG MD.
Specificity of creatine phosphokinase.
Nature. 175 (1955) 120. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:5750168]
Keutel HJ, Jacobs HK, Okabe K, Yue RH, Kuby SA.
Studies on adenosine triphosphate transphosphorylases. VII.
Isolation of the crystalline adenosine triphosphate--creatine
transphosphorylase from calf brain.
Biochemistry. 7 (1968) 4283-90.
Bos taurus [GN:bta] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:13192073]
KUBY SA, NODA L, LARDY HA.
Adenosinetriphosphate-creatine transphosphorylase. I. Isolation of
the crystalline enzyme from rabbit muscle.
J. Biol. Chem. 209 (1954) 191-201.
Oryctolagus cuniculus |
|---|
Reference
Authors
Title
Journal
|
4
Kuby, S.A. and Noltmann, E.A.
ATP-creatine transphosphorylase.
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
ed., vol. 6, Academic Press, New York, 1962, p. 515-603. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.7.3.2
IUBMB Enzyme Nomenclature: 2.7.3.2
ExPASy - ENZYME nomenclature database: 2.7.3.2
BRENDA, the Enzyme Database: 2.7.3.2
CAS: 9001-15-4 |
|---|
