| Entry |
|
|---|
| Name |
nucleoside-triphosphate---adenylate kinase;
guanosine triphosphate-adenylate kinase;
nucleoside triphosphate-adenosine monophosphate transphosphorylase;
GTP:AMP phosphotransferase;
isozyme 3 of adenylate kinase |
|---|
| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
 |
|---|
| Sysname |
nucleoside-triphosphate:AMP phosphotransferase |
|---|
| Reaction(IUBMB) |
nucleoside triphosphate + AMP = nucleoside diphosphate + ADP
[RN:R00333] |
|---|
| Reaction(KEGG) |
R00333 > R00157
 |
|---|
| Substrate |
nucleoside triphosphate [CPD:C00201];
AMP [CPD:C00020] |
|---|
| Product |
nucleoside diphosphate [CPD:C00454];
ADP [CPD:C00008] |
|---|
| Comment |
Many nucleoside triphosphates can act as donors. |
|---|
| Pathway |
PATH: ec00240 Pyrimidine metabolism |
|---|
| Orthology |
KO: K00944 nucleoside-triphosphate--adenylate kinase |
|---|
| Genes |
HSA: 50808(AK3)
PTR: 464977(AK3L1)
MCC: 694714
MMU: 56248(Ak3)
RNO: 26956(Ak3)
CFA: 480491(AK3L1) 608853
BTA: 281613(AK3L1)
MDO: 100014818
OAA: 100073575
GGA: 426534(AK3)
XLA: 414511
XTR: 100145221
DRE: 406404(ak3)
SPU: 583479
NVE: NEMVE_v1g184404
SSE: Ssed_2847(adk)
 |
|---|
| Structures |
PDB: 1ZD8 2AK3 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5423264]
Albrecht GJ.
Purification and properties of nucleoside triphosphate-adenosine
monophosphate transphosphorylase from beef heart mitochondria.
Biochemistry. 9 (1970) 2462-70.
Bos taurus [GN:bta] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13693071]
CHIGA M, ROGERS AE, PLAUT GW.
Nucleotide transphosphorylases from liver. II. Purification and
properties of a 6-oxypurine nucleoside triphosphate-adenosine
monophosphate transphosphorylase from swine liver.
J. Biol. Chem. 236 (1961) 1800-5.
Sus scofa [GN:ssc] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.7.4.10
IUBMB Enzyme Nomenclature: 2.7.4.10
ExPASy - ENZYME nomenclature database: 2.7.4.10
BRENDA, the Enzyme Database: 2.7.4.10
CAS: 9026-74-8 |
|---|
