| Entry |
|
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| Name |
ribose 1,5-bisphosphate phosphokinase;
ribose 1,5-bisphosphokinase;
PhnN |
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
 |
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| Sysname |
ATP:ribose-1,5-bisphosphate phosphotransferase |
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| Reaction(IUBMB) |
ATP + ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose
1-diphosphate [RN:R06836] |
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| Reaction(KEGG) |
R06836
 |
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| Substrate |
ATP [CPD:C00002];
ribose 1,5-bisphosphate [CPD:C01151] |
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| Product |
ADP [CPD:C00008];
5-phospho-alpha-D-ribose 1-diphosphate [CPD:C00119] |
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| Comment |
This enzyme, found in NAD supression mutants of Escherichia coli,
synthesizes 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) without
the participation of EC 2.7.6.1, ribose-phosphate diphosphokinase.
Ribose, ribose 1-phosphate and ribose 5-phosphate are not
substrates, and GTP cannot act as a phosphate donor. |
|---|
| Pathway |
PATH: ec00030 Pentose phosphate pathway |
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| Orthology |
KO: K05774 ribose 1,5-bisphosphokinase |
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| Genes |
ECO: b4094(phnN)
ECJ: JW4055(phnN)
ECD: ECDH10B_4285(phnN)
EBW: BWG_3809(phnN)
ECE: Z5697(phnN)
ECS: ECs5077
ECF: ECH74115_5607(phnN)
ETW: ECSP_5194(phnN)
ECG: E2348C_4423(phnN)
ECI: UTI89_C4689(phnN)
ECP: ECP_4337
ECV: APECO1_2356(phnN)
ECW: EcE24377A_4648(phnN)
ECX: EcHS_A4335(phnN)
ECM: EcSMS35_4560(phnN)
ECY: ECSE_4393
ECL: EcolC_3932
ECK: EC55989_4585(phnN)
ECQ: ECED1_4829(phnN)
ECR: ECIAI1_4324(phnN)
ECT: ECIAI39_4518(phnN)
ECZ: ECS88_4595(phnN)
EUM: ECUMN_4626(phnN)
ELF: LF82_1653(phnN)
EBL: B21_03926(phnN)
EBD: ECBD_3936
EBR: ECB_03966(phnN)
EOH: ECO103_4847(phnN)
EOI: ECO111_4965(phnN)
EOJ: ECO26_5207(phnN)
SES: SARI_03381
YPE: YPO3464(phnN)
YPK: y0721(phnN)
YPM: YP_0619(phnN)
YPA: YPA_2966
YPN: YPN_0623
YPG: YpAngola_A4024
YPP: YPDSF_3274
YPS: YPTB0509(phnN)
YPI: YpsIP31758_3567
YPY: YPK_3701
YPB: YPTS_0539
YEN: YE0470(phnN)
SSN: SSON_4270(phnN)
SBO: SBO_4120(phnN)
SDY: SDY_4122(phnN)
ECA: ECA0497(phnN)
PCT: PC1_0486
PWA: Pecwa_0582
ENT: Ent638_0298
KPN: KPN_04492(phnN)
KPE: KPK_5175(phnN)
KPU: KP1_0357(phnN)
CKO: CKO_03776
SPE: Spro_0514
DDA: Dd703_1315
DDC: Dd586_2592
DZE: Dd1591_2687
PAE: PA3373
PAU: PA14_20440(phnN)
PAP: PSPA7_1756(phnN)
PAG: PLES_16871(phnN)
PPU: PP_4469(gmk-1)
PPF: Pput_1446
PPG: PputGB1_3974
PPW: PputW619_3758
PST: PSPTO_2566(phnN)
PSB: Psyr_2258
PSP: PSPPH_2929(phnN)
PFO: Pfl01_4269
PFS: PFLU1788(phnN)
PEN: PSEEN3864(phnN)
PMY: Pmen_2879
PSA: PST_4122(phnN)
AVN: Avin_07830
SWD: Swoo_3892
MAQ: Maqu_0224 Maqu_2296 Maqu_4142
PIN: Ping_3685
TCX: Tcr_2089
AFE: Lferr_1933
AFR: AFE_2286
CVI: CV_1849(phnN)
REU: Reut_B4182
REH: H16_B1291(phnN)
RME: Rmet_0770
CTI: RALTA_B1194(phnN)
BMA: BMA2397(phnN)
BMV: BMASAVP1_A0313(phnN)
BML: BMA10229_A1174(phnN)
BMN: BMA10247_2583(phnN)
BPS: BPSL2860(phnN)
BPM: BURPS1710b_3359(phnN)
BPL: BURPS1106A_3349(phnN)
BPD: BURPS668_3315(phnN)
BPR: GBP346_A3491(phnN)
BXE: Bxe_B2176
BPH: Bphy_3770
BPY: Bphyt_5937
RFR: Rfer_0148
VEI: Veis_2955
DIA: Dtpsy_2927
VAP: Vapar_6101
MPT: Mpe_B0431(htxM)
TBD: Tbd_2289
DDE: Dde_3336
DBA: Dbac_0820
MLO: mll9141
MES: Meso_3660
SME: SM_b21170
SMD: Smed_4662
ATU: Atu0168(gmk)
ATC: AGR_C_277
ARA: Arad_0272(phnN)
AVI: Avi_0288(gmk)
RET: RHE_CH00154(gmk1)
REC: RHECIAT_CH0000198(phnN)
RLE: RL0163(phnN)
RLT: Rleg2_4111
RLG: Rleg_4425
RHI: NGR_b13280
BME: BMEI0882
BMF: BAB1_1123
BMB: BruAb1_1105
BMC: BAbS19_I10420
BMS: BR1099
BMT: BSUIS_A1148(phnN)
BOV: BOV_1060(phnN)
BCS: BCAN_A1119(phnN)
BMR: BMI_I1111
OAN: Oant_2188
BJA: blr1228(gmk)
BRA: BRADO5349(phnN)
BBT: BBta_5841(phnN)
RPA: RPA0688(phnN)
RPB: RPB_4096
RPC: RPC_1279
RPD: RPD_3832
RPE: RPE_3103
RPT: Rpal_0755
XAU: Xaut_1309
AZC: AZC_3400
MRD: Mrad2831_3849
MET: M446_2907
MNO: Mnod_4214
SIL: SPO0474(phnN)
SIT: TM1040_3697
JAN: Jann_2855
RDE: RD1_2388(phnN)
PDE: Pden_4776
ACR: Acry_2919
CMI: CMM_0372(phnN)
 |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:12700258]
Hove-Jensen B, Rosenkrantz TJ, Haldimann A, Wanner BL.
Escherichia coli phnN, encoding ribose 1,5-bisphosphokinase activity
(phosphoribosyl diphosphate forming): dual role in phosphonate
degradation and NAD biosynthesis pathways.
J. Bacteriol. 185 (2003) 2793-801.
Escherichia coli [GN:eco] |
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| Other DBs |
ExplorEnz - The Enzyme Database: 2.7.4.23
IUBMB Enzyme Nomenclature: 2.7.4.23
ExPASy - ENZYME nomenclature database: 2.7.4.23
BRENDA, the Enzyme Database: 2.7.4.23 |
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