KEGG   ENZYME: 2.7.4.4Help
Entry
EC 2.7.4.4                  Enzyme                                 

Name nucleoside-phosphate kinase;
NMP-kinase
Class Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
BRITE hierarchy
Sysname ATP:nucleoside-phosphate phosphotransferase
Reaction(IUBMB) ATP + nucleoside phosphate = ADP + nucleoside diphosphate
[RN:R00334]
Reaction(KEGG) R00334 > R00158 R02098
Show
Substrate ATP [CPD:C00002];
nucleoside phosphate [CPD:C01329]
Product ADP [CPD:C00008];
nucleoside diphosphate [CPD:C00454]
Comment Many nucleotides can act as acceptors; other nucleoside
triphosphates can act instead of ATP.
Pathway PATH: ec00240  Pyrimidine metabolism
Structures PDB: 2BND  2BNE  2BNF  
Reference
  Authors
  Title
  Journal
  Organism
1  [PMID:13363863]
AYENGAR P, GIBSON DM, SANADI DR.
Transphosphorylations between nucleoside phosphates.
Biochim. Biophys. Acta. 21 (1956) 86-91.
Sus scofa [GN:ssc]
Reference
  Authors
  Title

  Journal
  Organism
2  [PMID:14401179]
HEPPEL LA, STROMINGER JL, MAXWELL ES.
Nucleoside monophosphate kinases. II. Transphosphorylation betweeen
adenosine monophosphate and nucleoside triphosphates.
Biochim. Biophys. Acta. 32 (1959) 422-30.
Bos taurus [GN:bta]
Reference
  Authors
  Title
  Journal
  Organism
3  [PMID:14392176]
LIEBERMAN I, KORNBERG A, SIMMS ES.
Enzymatic synthesis of nucleoside diphosphates and triphosphates.
J. Biol. Chem. 215 (1955) 429-40.
Bos taurus [GN:bta]
Reference
  Authors
  Title
  Journal

4
Noda, L.
Nucleoside triphosphate-nucleoside monophosphokinases.
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
ed., vol. 6, Academic Press, New York, 1962, p. 139-149.
Other DBs ExplorEnz - The Enzyme Database: 2.7.4.4
IUBMB Enzyme Nomenclature: 2.7.4.4
ExPASy - ENZYME nomenclature database: 2.7.4.4
BRENDA, the Enzyme Database: 2.7.4.4
CAS: 9026-50-0

DBGET integrated database retrieval system