KEGG   ENZYME: 2.7.7.13Help
Entry
EC 2.7.7.13                 Enzyme                                 
Name mannose-1-phosphate guanylyltransferase;
GTP-mannose-1-phosphate guanylyltransferase;
PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose
pyrophosphorylase);
GDP-mannose pyrophosphorylase;
guanosine 5'-diphospho-D-mannose pyrophosphorylase;
guanosine diphosphomannose pyrophosphorylase;
guanosine triphosphate-mannose 1-phosphate guanylyltransferase;
mannose 1-phosphate guanylyltransferase (guanosine triphosphate)
Class Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname GTP:alpha-D-mannose-1-phosphate guanylyltransferase
Reaction(IUBMB) GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose
[RN:R00885]
Reaction(KEGG) R00885
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Substrate GTP [CPD:C00044];
alpha-D-mannose 1-phosphate [CPD:C00636]
Product diphosphate [CPD:C00013];
GDP-mannose [CPD:C00096]
Comment The bacterial enzyme can also use ITP and dGTP as donors.
Pathway PATH: ec00051  Fructose and mannose metabolism
PATH: ec00520  Amino sugar and nucleotide sugar metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K00966  mannose-1-phosphate guanylyltransferase
Genes XLA: 447346
XTR: 493267(gmppb)
DRE: 445097
DME: Dmel_CG1129 Dmel_CG8207
DPO: Dpse_GA10892 Dpse_GA20898
AME: 409329
CEL: C42C1.5(tag-335)
NVE: NEMVE_v1g162365
CME: CML145C CMO003C
SCE: YDL055C(PSA1)
AGO: AGOS_AFR599W
DHA: DEHA0E16544g DEHA0F01265g
PIC: PICST_74665(MPG1)
CGR: CAGL0D01034g CAGL0H04983g
YLI: YALI0C06490g
SPO: SPBC13G1.02 SPCC1906.01(mpg1)
NCR: NCU11213
MGR: MGG_01288
ANI: AN5586.2
AFM: AFUA_4G11510 AFUA_6G07620
AOR: AO090003000189 AO090003001069
ANG: An04g04990
CNE: CNC03020
ECU: ECU11_0690
DDI: DDB_0231665(mpgA)
PFA: PF14_0774
TAN: TA14300
TPV: TP02_0639
CPV: cgd2_1770
CHO: Chro.20192
TET: TTHERM_00628710
TBR: Tb927.8.2050
TCR: 503589.10 510947.10
LMA: LmjF23.0110
TVA: TVAG_394720
XFA: XF0591
XFT: PD1560
XCC: XCC2785(glgC)
XCB: XC_1328
XCV: XCV3100
XAC: XAC2955
XOO: XOO1302
XOM: XOO_1202
SML: Smlt1130
VVU: VV1_0804
VFI: VF_0145
PPF: Pput_0440
PSP: PSPPH_0638
PFL: PFL_5644
PFO: Pfl01_5130
PEN: PSEEN0433 PSEEN2466
ABM: ABSDF0072
SAZ: Sama_2335 Sama_2814
PHA: PSHAa2630
MAQ: Maqu_3512
FTW: FTW_0453
TCX: Tcr_1456 Tcr_1652
NOC: Noc_2431
RMA: Rmag_0467
CVI: CV_4226
REU: Reut_A0722
BUR: Bcep18194_A6040
RFR: Rfer_0712
HAR: HEAR0727
NET: Neut_0159
AZO: azo2231
DAR: Daro_3661
TDN: Suden_0175
CJJ: CJJ81176_1422
SUN: SUN_1275
GSU: GSU3254
GME: Gmet_3178
GUR: Gura_0855 Gura_4088
GLO: Glov_0407
GBM: Gbem_3402
GEO: Geob_1007
GEM: GM21_3465
PCA: Pcar_2958(mpg)
PPD: Ppro_0028
DVL: Dvul_2585
BBA: Bd0153 Bd1685
SAT: SYN_01129
MLO: mlr6764
RLE: RL0028
BME: BMEI2025
BMF: BAB1_2103
BRA: BRADO0082 BRADO5165
BBT: BBta_0088 BBta_5632
RPA: RPA3919
RPB: RPB_3804
RPE: RPE_0462
NWI: Nwi_0048 Nwi_2394
MEX: Mext_3557
RDE: RD1_0454
SAL: Sala_0159
GBE: GbCGDNIH1_2008
RRU: Rru_A3436
MGM: Mmc1_0560 Mmc1_0963
BHA: BH1416(mpg)
BAN: BA4491
BAR: GBAA4491
BAA: BA_4938
BAT: BAS4169
BAH: BAMEG_4528
BAI: BAA_4510
BCE: BC4264
BCA: BCE_4347
BCZ: BCZK4017
BCR: BCAH187_A4400
BCB: BCB4264_A4381
BCU: BCAH820_4287
BCG: BCG9842_B0853
BCQ: BCQ_4052
BCX: BCA_4378
BCY: Bcer98_2995
BTK: BT9727_4007
BTL: BALH_3860
BWE: BcerKBAB4_4120
GKA: GK0360
GTN: GTNG_0335(manC)
AFL: Aflv_0886
BBE: BBR47_37850
CAC: CAC2981 CAC3056
CKL: CKL_0995
CKR: CKR_0899 CKR_1651
CCE: Ccel_0348 Ccel_1940
AMT: Amet_3538
STH: STH1120
SWO: Swol_2137
ATE: Athe_0233
DSY: DSY4439
DRM: Dred_2334
DAE: Dtox_0788
DAU: Daud_1040
HMO: HM1_3137
TTE: TTE0065(gcd1) TTE2013(Gcd1.2)
TEX: Teth514_1013
TPD: Teth39_0529
MTA: Moth_0757 Moth_1925
HOR: Hore_15980
MTU: Rv3264c(manB)
MTC: MT3364(mpg1)
MLE: ML0753(rmlA2)
MPA: MAP3378c(rmlA2)
MAV: MAV_4228
MUL: MUL_2610(manB)
MVA: Mvan_1729
MGI: Mflv_4734
MAB: MAB_3611c
MMC: Mmcs_1321
MJL: Mjls_1357
CGL: NCgl0710(cgl0742)
CGT: cgR_0851
CEF: CE0756
CDI: DIP0682
CJK: jk1645
RHA: RHA1_ro06307
SCO: SCO1388(SC1A8A.08c) SCO3039(SCE34.20c)
SMA: SAV_358(mpg1) SAV_5037(rmlA) SAV_6977(mpg3)
SGR: SGR_6141
TFU: Tfu_1394
TCU: Tcur_2437
SRO: Sros_4001
FRA: Francci3_0737 Francci3_1463
FRE: Franean1_5002
FAL: FRAAL1255 FRAAL2265
SEN: SACE_6470(manB)
AFO: Afer_1123
LIL: LA1581 LA1611
LIC: LIC12171 LIC12201
BTH: BT_1633
BFR: BF1436
AMU: Amuc_1919
SYN: sll1496 sll1558
SYW: SYNW2266
SYC: syc1022_c syc2123_d
SYF: Synpcc7942_0498 Synpcc7942_1973
SYD: Syncc9605_2404
SYE: Syncc9902_0289
SYG: sync_2617
SYR: SynRCC307_0228
SYX: SynWH7803_2282
SYP: SYNPCC7002_A0950 SYNPCC7002_A1389
CYA: CYA_1231
CYB: CYB_1549
TEL: tlr0436 tlr0611
MAR: MAE_40260
CYT: cce_0336 cce_2061
CYC: PCC7424_0525
CYN: Cyan7425_1501
CYH: Cyan8802_2912
GVI: gll2200 gll3084 gll3341 gll3703 glr0471 gvip246(rfbM)
     gvip473(rfbM)
ANA: alr2361 alr3400
NPU: Npun_R6155
AVA: Ava_0182 Ava_3422
PMA: Pro0175(GCD1)
PMM: PMM0152
PMT: PMT2012
PMN: PMN2A_1518
PMI: PMT9312_0154
PMB: A9601_01691 A9601_14401
PMC: P9515_01801
PMF: P9303_00981 P9303_01171 P9303_26731
PMG: P9301_01711 P9301_14051
PMH: P9215_01691(gcd1)
PME: NATL1_02241
TER: Tery_1143 Tery_3188
AMR: AM1_2170
CTE: CT2056
CCH: Cag_0193
CPH: Cpha266_0204
PVI: Cvib_1649
PLT: Plut_2007
CTS: Ctha_0525
DEH: cbdb_A1125
RRS: RoseRS_4397
RCA: Rcas_0740
CAU: Caur_2960
CAG: Cagg_3774
CHL: Chy400_3205
HAU: Haur_3420
DRA: DR_0710
AAE: aq_718(mpg)
SUL: SYO3AOP1_1001
SAF: SULAZ_1017
DTH: DICTH_1322
DTU: Dtur_1427
MAC: MA3140(rfbM)
MBA: Mbar_A1937
MMA: MM_0378
MBU: Mbur_2250
MHU: Mhun_2619
MLA: Mlab_1310
MEM: Memar_1993
MBN: Mboo_1899
MPL: Mpal_2168
MTH: MTH1759
MKA: MK0917
HWA: HQ3261A(manC)
TAC: Ta1486
TVO: TVN0081
PTO: PTO0702
PHO: PH1022 PH1697
PAB: PAB0317(mpg) PAB0645
PFU: PF0868 PF1728
TKO: TK0955
TON: TON_0659
RCI: RCIX300(rfbM)
APE: APE_0255.1
DKA: DKAM_0111
SSO: SSO0317
STO: ST2284
SAI: Saci_0196(mpg1)
MSE: Msed_1890
PAI: PAE3554
PIS: Pisl_0928
PCL: Pcal_1971
PAS: Pars_1620
CMA: Cmaq_0561
TNE: Tneu_0890
NMR: Nmar_0541
Taxonomy
Structures PDB: 2CU2  
Reference
  Authors
  Title

  Journal
 1
Munch-Peterson, A.
Enzymatic synthesis and phosphorolysis of guanosine diphosphate
mannose.
Arch. Biochem. Biophys. 55 (1955) 592-593.
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:14245350]
PREISS J, WOOD E.
SUGAR NUCLEOTIDE REACTIONS IN ARTHROBACTER. I. GUANOSINE DIPHOSPHATE
MANNOSE PYROPHOSPHORYLASE: PURIFICATION AND PROPERTIES.
J. Biol. Chem. 239 (1964) 3119-26.
Arthrobacter sp.
Other DBs ExplorEnz - The Enzyme Database: 2.7.7.13
IUBMB Enzyme Nomenclature: 2.7.7.13
ExPASy - ENZYME nomenclature database: 2.7.7.13
BRENDA, the Enzyme Database: 2.7.7.13
CAS: 37278-24-3
DBGET integrated database retrieval system