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Entry
EC 2.7.7.14                 Enzyme                                 

Name ethanolamine-phosphate cytidylyltransferase;
phosphorylethanolamine transferase;
ET;
CTP-phosphoethanolamine cytidylyltransferase;
phosphoethanolamine cytidylyltransferase;
ethanolamine phosphate cytidylyltransferase
Class Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname CTP:ethanolamine-phosphate cytidylyltransferase
Reaction(IUBMB) CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine
[RN:R02038]
Reaction(KEGG) R02038;
(other) R04247
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Substrate CTP [CPD:C00063];
ethanolamine phosphate [CPD:C00346]
Product diphosphate [CPD:C00013];
CDP-ethanolamine [CPD:C00570]
Pathway PATH: ec00440  Phosphonate and phosphinate metabolism
PATH: ec00564  Glycerophospholipid metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K00967  ethanolamine-phosphate cytidylyltransferase
Genes HSA: 5833(PCYT2)
PTR: 454974(PCYT2)
MCC: 715006(PCYT2)
MMU: 68671(Pcyt2)
RNO: 89841(Pcyt2)
CFA: 607608(PCYT2)
BTA: 510274(PCYT2)
ECB: 100055008
MDO: 100030076
XLA: 444649
XTR: 496753(pcyt2)
DRE: 450016
BFO: BRAFLDRAFT_113520 BRAFLDRAFT_263704 BRAFLDRAFT_263711
     BRAFLDRAFT_82871
CIN: 100179011
SPU: 582687 587421
DME: Dmel_CG5547(Pect)
DPO: Dpse_GA28810
DAN: Dana_GF15564
DER: Dere_GG23821
DPE: Dper_GL26305
DSE: Dsec_GM10235
DSI: Dsim_GD23872
DYA: Dyak_GE18624(Dyak_Pect)
DGR: Dgri_GH11091
DMO: Dmoj_GI17607
AGA: AgaP_AGAP009264
AAG: AaeL_AAEL005651
CQU: CpipJ_CPIJ009320
AME: 551931
NVI: 100117898
TCA: 654972 661364
API: 100161708
ISC: IscW_ISCW023586
CEL: C39D10.3 Y37E3.11
CBR: CBG16841 CBG22040
BMY: Bm1_01855
NVE: NEMVE_v1g175500
HMG: 100207019
TAD: TRIADDRAFT_53627
ATH: AT2G38670(PECT1)
POP: POPTR_1104748 POPTR_736610 POPTR_801872 POPTR_809912
RCU: RCOM_0907340 RCOM_1323420
VVI: 100251543(GSVIVT00007159001) 100265603
OSA: 4344972(Os08g0224800) 4348512(Os10g0387000)
     4349636(Os11g0123400) 4351359(Os12g0121300)
SBI: SORBI_05g001470(SORBIDRAFT_05g001470)
PPP: PHYPADRAFT_121436 PHYPADRAFT_148429
CRE: CHLREDRAFT_136865(ECT1)
OLU: OSTLU_33520
CME: CMS052C
SCE: YGR007W(MUQ1)
AGO: AGOS_AFR504W
KLA: KLLA0C18139g
LTH: KLTH0E08712g
DHA: DEHA0A07128g
PIC: PICST_76493(MUQ1)
PPA: PAS_chr4_0408
VPO: Kpol_1062p40
LEL: LELG_01190
ZRO: ZYRO0G11088g
CAL: CaO19.2107(MUQ1) CaO19.9655(MUQ1)
CTP: CTRG_01086
CDU: CD36_15240
CGR: CAGL0F08723g
YLI: YALI0C06303g
SPO: SPAC15E1.05c
NCR: NCU04289
PAN: PODANSg8848
MGR: MGG_00943
FGR: FG04571.1
ANI: AN4303.2
AFM: AFUA_4G05940
AOR: AO090023001003
ANG: An04g00140
AFV: AFLA_114050
PCS: Pc20g00270
NFI: NFIA_110210
CIM: CIMG_04234
URE: UREG_05660
SSL: SS1G_10548
BFU: BC1G_10606
ECU: ECU11_0870
MBR: MONBRDRAFT_20281
DDI: DDB_0191331(pctA)
EHI: EHI_095120 EHI_140590
EDI: EDI_013070 EDI_204270
PFA: PF13_0253
PFH: PFHG_05091
PYO: PY06073
PCB: PC000551.01.0
PBE: PB000900.02.0
PKN: PKH_120620
PVX: PVX_083280
TAN: TA07160
TPV: TP04_0187
BBO: BBOV_I004300
CPV: cgd7_2950
CHO: Chro.70332
TET: TTHERM_00015980 TTHERM_00429910
PTM: GSPATT00027630001 GSPATT00032795001
TBR: Tb11.01.5730
TCR: 511727.120
LMA: LmjF32.0890
LIF: LinJ32.1290
LBZ: LbrM32_V2.0980
TVA: TVAG_327610
PTI: PHATRDRAFT_40163
TPS: THAPSDRAFT_42946
Taxonomy
Structures PDB: 3ELB  
Reference
  Authors
  Title

  Journal
  Organism
1  [PMID:13366993]
KENNEDY EP, WEISS SB.
The function of cytidine coenzymes in the biosynthesis of
phospholipides.
J. Biol. Chem. 222 (1956) 193-214.
Rattus norvegicus [GN:rno]
Reference
  Authors
  Title

  Journal
  Organism
2  [PMID:241749]
Sundler R.
Ethanolaminephosphate cytidylyltransferase. Purification and
characterization of the enzyme from rat liver.
J. Biol. Chem. 250 (1975) 8585-90.
Rattus norvegicus [GN:rno]
Reference
  Authors
  Title


  Journal
  Organism
3  [PMID:2549956]
Visedo-Gonzalez E, Dixon HB.
2-Aminoethylarsonic acid as an analogue of ethanolamine phosphate.
Endowment of ethanolamine-phosphate cytidylyltransferase with CTP
pyrophosphatase activity.
Biochem. J. 260 (1989) 299-301.
Rattus norvegicus [GN:rno]
Other DBs ExplorEnz - The Enzyme Database: 2.7.7.14
IUBMB Enzyme Nomenclature: 2.7.7.14
ExPASy - ENZYME nomenclature database: 2.7.7.14
BRENDA, the Enzyme Database: 2.7.7.14
CAS: 9026-33-9

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