| Entry |
|
|---|
| Name |
thiosulfate---thiol sulfurtransferase;
glutathione-dependent thiosulfate reductase;
sulfane reductase;
sulfane sulfurtransferase |
|---|
| Class |
Transferases;
Transferring sulfur-containing groups;
Sulfurtransferases
 |
|---|
| Sysname |
thiosulfate:thiol sulfurtransferase |
|---|
| Reaction(IUBMB) |
thiosulfate + 2 glutathione = sulfite + glutathione disulfide +
sulfide [RN:R01875] |
|---|
| Reaction(KEGG) |
R01875
 |
|---|
| Substrate |
thiosulfate [CPD:C00320];
glutathione [CPD:C00051] |
|---|
| Product |
sulfite [CPD:C00094];
glutathione disulfide [CPD:C00127];
sulfide [CPD:C00283] |
|---|
| Comment |
The primary product is glutathione hydrodisulfide, which reacts with
glutathione to give glutathione disulfide and sulfide. L-Cysteine
can also act as acceptor. |
|---|
| Pathway |
PATH: ec00480 Glutathione metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14484816]
PECK HD Jr, FISHER E Jr.
The oxidation of thiosulfate and phosphorylation in extracts of
Thiobacillus thioparus.
J. Biol. Chem. 237 (1962) 190-7.
Thiobacillus thioparus |
|---|
Reference
Authors
Title
Journal
|
2
Sido, B. and Koj, A.
Separation of rhodanese and thiosulfate reductase activities in carp
liver extracts.
Acta Biol. Cracow Ser. Zoo. 15 (1972) 97-103. |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:383018]
Uhteg LC, Westley J.
Purification and steady-state kinetic analysis of yeast thiosulfate
reductase.
Arch. Biochem. Biophys. 195 (1979) 211-22.
Saccharomyces cerevisiae [GN:sce] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.8.1.3
IUBMB Enzyme Nomenclature: 2.8.1.3
ExPASy - ENZYME nomenclature database: 2.8.1.3
BRENDA, the Enzyme Database: 2.8.1.3
CAS: 111070-24-7 |
|---|
