| Entry |
|
|---|
| Name |
thiosulfate---dithiol sulfurtransferase;
thiosulfate reductase;
TSR |
|---|
| Class |
Transferases;
Transferring sulfur-containing groups;
Sulfurtransferases
 |
|---|
| Sysname |
thiosulfate:dithioerythritol sulfurtransferase |
|---|
| Reaction(IUBMB) |
thiosulfate + dithioerythritol = sulfite +
4,5-cis-dihydroxy-1,2-dithiacyclohexane (i.e. oxidized
dithioerythritol) + sulfide |
|---|
| Reaction(KEGG) |
(other) R05072
 |
|---|
| Substrate |
thiosulfate [CPD:C00320];
dithioerythritol [CPD:C00950] |
|---|
| Product |
sulfite [CPD:C00094];
4,5-cis-dihydroxy-1,2-dithiacyclohexane [CPD:C06484];
sulfide [CPD:C00283] |
|---|
| Comment |
The enzyme from Chlorella shows very little activity towards
monothiols such as glutathione and cysteine (cf. EC 2.8.1.3
thiosulfate---thiolsulfurtransferase). The enzyme probably transfers
the sulfur atom onto one thiol group to form -S-S-, and sulfide is
spontaneously expelled from this by reaction with the other thiol
group. May be identical with EC 2.8.1.1 thiosulfate
sulfurtransferase. |
|---|
| Pathway |
PATH: ec00920 Sulfur metabolism |
|---|
Reference
Authors
Title
Journal
|
1
Schmidt, A., Erdle, I. and Gamon, B.
Isolation and characterization of thiosulfate reductases from the
green alga Chlorella fusca.
Planta 162 (1984) 243-249. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.8.1.5
IUBMB Enzyme Nomenclature: 2.8.1.5
ExPASy - ENZYME nomenclature database: 2.8.1.5
BRENDA, the Enzyme Database: 2.8.1.5
CAS: 9059-49-8 |
|---|
