| Entry |
|
|---|
| Name |
chondroitin 6-sulfotransferase;
chondroitin 6-O-sulfotransferase;
3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate
sulfotransferase;
terminal 6-sulfotransferase |
|---|
| Class |
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
 |
|---|
| Sysname |
3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase |
|---|
| Reaction(IUBMB) |
3'-phosphoadenylyl sulfate + chondroitin = adenosine
3',5'-bisphosphate + chondroitin 6'-sulfate [RN:R02181] |
|---|
| Reaction(KEGG) |
R02181
 |
|---|
| Substrate |
3'-phosphoadenylyl sulfate [CPD:C00053];
chondroitin [CPD:C00401] |
|---|
| Product |
adenosine 3',5'-bisphosphate [CPD:C00054];
chondroitin 6'-sulfate [CPD:C00635] |
|---|
| Comment |
The sulfation is at the 6-position of N-acetylgalactosamine residues
of chondroitin. Not identical with EC 2.8.2.5 chondroitin
4-sulfotransferase. |
|---|
| Pathway |
PATH: ec00532 Chondroitin sulfate biosynthesis |
|---|
| Orthology |
KO: K01020 chondroitin 6-sulfotransferase 3
KO: K04743 chondroitin 6-sulfotransferase 7 |
|---|
| Genes |
HSA: 56548(CHST7) 9469(CHST3)
PTR: 466290(CHST3)
MCC: 704906(CHST7) 709333
MMU: 53374(Chst3) 60322(Chst7)
RNO: 302302(Chst7) 84468(Chst3)
CFA: 489036(CHST3) 491852(CHST7)
BTA: 506758(CHST3) 540357(CHST7)
SSC: 100151968
ECB: 100063554
MDO: 100010061 100011790
GGA: 396018(CHST3)
TGU: 100229231
XLA: 734885
DRE: 556800 559721(CH211-232K3.6) 563748
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6957247]
Habuchi O, Miyashita N.
Separation and characterization of chondroitin 6-sulfotransferase
and chondroitin 4-sulfotransferase from chick embryo cartilage.
Biochim. Biophys. Acta. 717 (1982) 414-21.
Gallus gallus [GN:gga] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.8.2.17
IUBMB Enzyme Nomenclature: 2.8.2.17
ExPASy - ENZYME nomenclature database: 2.8.2.17
BRENDA, the Enzyme Database: 2.8.2.17
CAS: 37292-93-6 |
|---|
