KEGG   ENZYME: 2.8.2.2Help
Entry
EC 2.8.2.2                  Enzyme                                 
Name
alcohol sulfotransferase;
hydroxysteroid sulfotransferase;
3beta-hydroxy steroid sulfotransferase;
Delta5-3beta-hydroxysteroid sulfokinase;
3-hydroxysteroid sulfotransferase;
HST;
5alpha-androstenol sulfotransferase;
cholesterol sulfotransferase;
dehydroepiandrosterone sulfotransferase;
estrogen sulfokinase;
estrogen sulfotransferase;
steroid alcohol sulfotransferase;
steroid sulfokinase;
steroid sulfotransferase;
sterol sulfokinase;
sterol sulfotransferase;
alcohol/hydroxysteroid sulfotransferase;
3beta-hydroxysteroid sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:alcohol sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate [RN:R00629]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
alcohol [CPD:C00069]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
alkyl sulfate [CPD:C02000]
Comment
Primary and secondary alcohols, including aliphatic alcohols, ascorbic acid, chloramphenicol, ephedrine and hydroxysteroids, but not phenolic steroids, can act as acceptors (cf. EC 2.8.2.15 steroid sulfotransferase).
Pathway
Steroid hormone biosynthesis
Sulfur metabolism
Microbial metabolism in diverse environments
Orthology
K01015  
alcohol sulfotransferase
Genes
HSA: 
6820(SULT2B1)
PTR: 
747360(SULT2B1)
PPS: 
100993458(SULT2B1)
GGO: 
101129679(SULT2B1)
PON: 
100441770(SULT2B1)
MCC: 
MMU: 
54200(Sult2b1)
RNO: 
292915(Sult2b1)
CFA: 
484403(SULT2B1)
AML: 
FCA: 
101086863(SULT2B1)
BTA: 
531192(SULT2B1)
SSC: 
100626471(SULT2B1)
MDO: 
100015166 100032213
SHR: 
100933402
OAA: 
100080450 100091264 100091660
GGA: 
426825 769841
ACS: 
100562572
XLA: 
496246(sult2a1)
XTR: 
100144988(sult2a1)
DRE: 
777792(sult2st3)
TRU: 
101064704
OLA: 
101168609
SME: 
SM_b21249
 » show all
Taxonomy
Reference
1  [PMID:6935986]
  Authors
Lyon ES, Jakoby WB.
  Title
The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases.
  Journal
Arch. Biochem. Biophys. 202 (1980) 474-81.
  Organism
Rattus norvegicus [GN:rno]
Reference
2  [PMID:6173569]
  Authors
Lyon ES, Marcus CJ, Wang JL, Jakoby WB.
  Title
Hydroxysteroid sulfotransferase.
  Journal
Methods. Enzymol. 77 (1981) 206-13.
  Organism
Rattus norvegicus [GN:rno]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9032-76-2
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