KEGG   ENZYME: 2.8.2.2Help
Entry
EC 2.8.2.2                  Enzyme                                 

Name
alcohol sulfotransferase;
hydroxysteroid sulfotransferase;
3beta-hydroxy steroid sulfotransferase;
Delta5-3beta-hydroxysteroid sulfokinase;
3-hydroxysteroid sulfotransferase;
HST;
5alpha-androstenol sulfotransferase;
cholesterol sulfotransferase;
dehydroepiandrosterone sulfotransferase;
estrogen sulfokinase;
estrogen sulfotransferase;
steroid alcohol sulfotransferase;
steroid sulfokinase;
steroid sulfotransferase;
sterol sulfokinase;
sterol sulfotransferase;
alcohol/hydroxysteroid sulfotransferase;
3beta-hydroxysteroid sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:alcohol sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate [RN:R00629]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
alcohol [CPD:C00069]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
alkyl sulfate [CPD:C02000]
Comment
Primary and secondary alcohols, including aliphatic alcohols, ascorbic acid, chloramphenicol, ephedrine and hydroxysteroids, but not phenolic steroids, can act as acceptors (cf. EC 2.8.2.15 steroid sulfotransferase).
History
EC 2.8.2.2 created 1961, modified 1980
Pathway
Steroid hormone biosynthesis
Orthology
K01015  
alcohol sulfotransferase
Genes
HSA: 
6820(SULT2B1)
PTR: 
747360(SULT2B1)
PPS: 
100993458(SULT2B1)
GGO: 
101129679(SULT2B1)
PON: 
100441770(SULT2B1)
MCC: 
MCF: 
102147126(SULT2B1)
MMU: 
54200(Sult2b1)
RNO: 
292915(Sult2b1)
CGE: 
100774216(Sult2b1)
HGL: 
101723933(Sult2b1)
TUP: 
102477821(SULT2B1)
CFA: 
484403(SULT2B1)
AML: 
FCA: 
101086863(SULT2B1)
BTA: 
531192(SULT2B1)
BOM: 
102284976(SULT2B1)
PHD: 
102323269(SULT2B1)
CHX: 
102183905(SULT2B1)
OAS: 
101122543(SULT2B1)
SSC: 
100626471(SULT2B1)
CFR: 
102503575(SULT2B1)
BACU: 
103009833(SULT2B1)
LVE: 
103078205(SULT2B1)
ECB: 
100147584(SULT2B1)
MYB: 
102258569(SULT2B1)
MYD: 
102766101(SULT2B1)
PALE: 
102887796(SULT2B1)
MDO: 
SHR: 
OAA: 
GGA: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
447414 496246(sult2a1)
XTR: 
DRE: 
777792(sult2st3)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
SME: 
 » show all
Taxonomy
Reference
1  [PMID:6935986]
  Authors
Lyon ES, Jakoby WB.
  Title
The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases.
  Journal
Arch. Biochem. Biophys. 202 (1980) 474-81.
Reference
2  [PMID:6173569]
  Authors
Lyon ES, Marcus CJ, Wang JL, Jakoby WB.
  Title
Hydroxysteroid sulfotransferase.
  Journal
Methods. Enzymol. 77 (1981) 206-13.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9032-76-2

DBGET integrated database retrieval system