| Entry |
|
|---|
| Name |
alcohol sulfotransferase;
hydroxysteroid sulfotransferase;
3beta-hydroxy steroid sulfotransferase;
Delta5-3beta-hydroxysteroid sulfokinase;
3beta-hydroxy steroid sulfotransferase;
3-hydroxysteroid sulfotransferase;
HST;
5alpha-androstenol sulfotransferase;
cholesterol sulfotransferase;
dehydroepiandrosterone sulfotransferase;
estrogen sulfokinase;
estrogen sulfotransferase;
steroid alcohol sulfotransferase;
steroid sulfokinase;
steroid sulfotransferase;
sterol sulfokinase;
sterol sulfotransferase;
alcohol/hydroxysteroid sulfotransferase;
3beta-hydroxysteroid sulfotransferase |
|---|
| Class |
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
 |
|---|
| Sysname |
3'-phosphoadenylyl-sulfate:alcohol sulfotransferase |
|---|
| Reaction(IUBMB) |
3'-phosphoadenylyl sulfate + an alcohol = adenosine
3',5'-bisphosphate + an alkyl sulfate [RN:R00629] |
|---|
| Reaction(KEGG) |
R00629 > R03405 R08977 R08978
 |
|---|
| Substrate |
3'-phosphoadenylyl sulfate [CPD:C00053];
alcohol [CPD:C00069] |
|---|
| Product |
adenosine 3',5'-bisphosphate [CPD:C00054];
alkyl sulfate [CPD:C02000] |
|---|
| Comment |
Primary and secondary alcohols, including aliphatic alcohols,
ascorbic acid, chloramphenicol, ephedrine and hydroxysteroids, but
not phenolic steroids, can act as acceptors (cf. EC 2.8.2.15 steroid
sulfotransferase). |
|---|
| Pathway |
PATH: ec00140 Steroid hormone biosynthesis
PATH: ec00920 Sulfur metabolism |
|---|
| Orthology |
KO: K01015 alcohol sulfotransferase |
|---|
| Genes |
HSA: 6820(SULT2B1)
PTR: 747360(SULT2B1)
MCC: 718739
MMU: 54200(Sult2b1)
RNO: 292915(Sult2b1) 361510(Sult2a2)
CFA: 484403(SULT2B1)
BTA: 531192(SULT2B1)
MDO: 100015166 100032213
GGA: 426825
XLA: 496246
XTR: 100144988
SME: SM_b21249
 |
|---|
| Structures |
PDB: 1EFH 1J99 1OV4 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6935986]
Lyon ES, Jakoby WB.
The identity of alcohol sulfotransferases with hydroxysteroid
sulfotransferases.
Arch. Biochem. Biophys. 202 (1980) 474-81.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6173569]
Lyon ES, Marcus CJ, Wang JL, Jakoby WB.
Hydroxysteroid sulfotransferase.
Methods. Enzymol. 77 (1981) 206-13.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.8.2.2
IUBMB Enzyme Nomenclature: 2.8.2.2
ExPASy - ENZYME nomenclature database: 2.8.2.2
BRENDA, the Enzyme Database: 2.8.2.2
CAS: 9032-76-2 |
|---|
