KEGG   ENZYME: 2.8.2.4Help
Entry
EC 2.8.2.4                  Enzyme                                 

Name
estrone sulfotransferase;
3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase;
estrogen sulfotransferase;
estrogen sulphotransferase;
oestrogen sulphotransferase;
3'-phosphoadenylylsulfate:oestrone sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate [RN:R02350]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
estrone [CPD:C00468]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
estrone 3-sulfate [CPD:C02538]
History
EC 2.8.2.4 created 1965
Pathway
Steroid hormone biosynthesis
Orthology
K01016  
estrone sulfotransferase
Genes
HSA: 
6783(SULT1E1)
PTR: 
461284(SULT1E1)
PPS: 
100972770(SULT1E1)
GGO: 
101142110(SULT1E1)
PON: 
100452192(SULT1E1)
MCC: 
708519(SULT1E1)
MCF: 
102121142(SULT1E1)
MMU: 
20860(Sult1e1)
RNO: 
25355(Sult1e1) 360268(ste2)
HGL: 
101715367(Sult1e1)
TUP: 
102468843(SULT1E1)
CFA: 
482182(SULT1E1)
AML: 
FCA: 
101086305(SULT1E1)
PTG: 
102969483(SULT1E1)
BTA: 
280934(SULT1E1)
BOM: 
102280512(SULT1E1)
PHD: 
102340807(SULT1E1)
CHX: 
102169846(SULT1E1)
OAS: 
101120331(SULT1E1)
SSC: 
397052(SULT1E1)
CFR: 
102520382(SULT1E1)
BACU: 
103010557(SULT1E1)
LVE: 
103078062(SULT1E1)
ECB: 
100034106(SULT1E1)
MYB: 
102247493(SULT1E1)
MYD: 
102756613(SULT1E1)
PALE: 
102897942(SULT1E1)
MDO: 
OAA: 
100081825(SULT1E1)
GGA: 
422662(SULT1E1)
MGP: 
XLA: 
734332(sult1e1)
XTR: 
733517(sult1e1)
DPO: 
 » show all
Taxonomy
Reference
1  [PMID:4965224]
  Authors
Adams JB, Poulos A.
  Title
Enzymic synthesis of steroid sulphates. 3. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands.
  Journal
Biochim. Biophys. Acta. 146 (1967) 493-508.
Reference
2  [PMID:903358]
  Authors
Rozhin J, Huo A, Zemlicka J, Brooks SC.
  Title
Studies on bovine adrenal estrogen sulfotransferase. Inhibition and possible involvement of adenine-estrogen stacking.
  Journal
J. Biol. Chem. 252 (1977) 7214-20.
Reference
3  [PMID:4473218]
  Authors
Adams JB, Ellyard RK, Low J.
  Title
Enzymic synthesis of steroid sulphates. IX. Physical and chemical properties of purified oestrogen sulphotransferase from bovine adrenal glands, the nature of its isoenzymic forms and a proposed model to explain its wave-like kinetics.
  Journal
Biochim. Biophys. Acta. 370 (1974) 160-88.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9026-06-6

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