KEGG   ENZYME: 2.8.2.4Help
Entry
EC 2.8.2.4                  Enzyme                                 
Name
estrone sulfotransferase;
3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase;
estrogen sulfotransferase;
estrogen sulphotransferase;
oestrogen sulphotransferase;
3'-phosphoadenylylsulfate:oestrone sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate [RN:R02350]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
estrone [CPD:C00468]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
estrone 3-sulfate [CPD:C02538]
Pathway
Steroid hormone biosynthesis
Sulfur metabolism
Orthology
K01016  
estrone sulfotransferase
Genes
HSA: 
6783(SULT1E1)
PTR: 
461284(SULT1E1)
PPS: 
100972770(SULT1E1)
GGO: 
101142110(SULT1E1)
PON: 
100452192(SULT1E1)
MCC: 
708519(SULT1E1)
MMU: 
20860(Sult1e1)
RNO: 
25355(Sult1e1)
CFA: 
482182(SULT1E1)
AML: 
FCA: 
101086305(SULT1E1)
BTA: 
280934(SULT1E1)
SSC: 
397052(SULT1E1)
ECB: 
100034106(SULT1E1)
MDO: 
100010148
OAA: 
100081825
GGA: 
422662(SULT1E1)
MGP: 
100549463
XLA: 
734332(sult1e1)
XTR: 
733517(sult1e1)
DPO: 
Dpse_GA14114
 » show all
Taxonomy
Reference
1  [PMID:4965224]
  Authors
Adams JB, Poulos A.
  Title
Enzymic synthesis of steroid sulphates. 3. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands.
  Journal
Biochim. Biophys. Acta. 146 (1967) 493-508.
  Organism
Bos taurus [GN:bta]
Reference
2  [PMID:903358]
  Authors
Rozhin J, Huo A, Zemlicka J, Brooks SC.
  Title
Studies on bovine adrenal estrogen sulfotransferase. Inhibition and possible involvement of adenine-estrogen stacking.
  Journal
J. Biol. Chem. 252 (1977) 7214-20.
  Organism
Bos taurus [GN:bta]
Reference
3  [PMID:4473218]
  Authors
Adams JB, Ellyard RK, Low J.
  Title
Enzymic synthesis of steroid sulphates. IX. Physical and chemical properties of purified oestrogen sulphotransferase from bovine adrenal glands, the nature of its isoenzymic forms and a proposed model to explain its wave-like kinetics.
  Journal
Biochim. Biophys. Acta. 370 (1974) 160-88.
  Organism
Bos taurus [GN:bta]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9026-06-6
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