KEGG   ENZYME: 2.9.1.1Help
Entry
EC 2.9.1.1                  Enzyme                                 
Name L-seryl-tRNASec selenium transferase;
L-selenocysteinyl-tRNASel synthase;
L-selenocysteinyl-tRNASec synthase selenocysteine synthase;
cysteinyl-tRNASec-selenium transferase;
cysteinyl-tRNASec-selenium transferase
Class Transferases;
Transferring selenium-containing groups;
Selenotransferases
BRITE hierarchy
Sysname selenophosphate:L-seryl-tRNASec selenium transferase
Reaction(IUBMB) L-seryl-tRNASec + selenophosphate = L-selenocysteinyl-tRNASec +
phosphate [RN:R08219]
Reaction(KEGG) R08219
Show
Substrate L-seryl-tRNA(Sec) [CPD:C06481];
selenophosphate [CPD:C05172]
Product L-selenocysteinyl-tRNA(Sec) [CPD:C06482];
phosphate [CPD:C00009]
Cofactor Pyridoxal phosphate [CPD:C00018]
Comment A pyridoxal 5'-phosphate enzyme identified in Escherichia coli.
Recognises specifically tRNASec-species. Binding of tRNASec also
occurs in the absence of the seryl group. 2-Aminoacryloyl-tRNA,
bound to the enzyme as an imine with the pyridoxal phosphate, is an
intermediate in the reaction. Since the selenium atom replaces
oxygen in serine, the product may also be referred to as
L-selenoseryl-tRNASec. The symbol Sel has also been used for
selenocysteine but Sec is preferred.
Pathway PATH: ec00450  Selenoamino acid metabolism
PATH: ec00970  Aminoacyl-tRNA biosynthesis
PATH: ec01100  Metabolic pathways
Orthology KO: K01042  L-seryl-tRNA(Ser) seleniumtransferase
Genes ECO: b3591(selA)
ECJ: JW3564(selA)
EBW: BWG_3281(selA)
ECE: Z5012(selA)
ECS: ECs4468
ECF: ECH74115_4962(selA)
ETW: ECSP_4584(selA)
ECG: E2348C_3841(selA)
ECC: c4412(selA)
ECI: UTI89_C4133(selA)
ECP: ECP_3693
ECV: APECO1_2862(selA)
ECW: EcE24377A_3272 EcE24377A_4089(selA)
ECX: EcHS_A3796(selA)
ECM: EcSMS35_3919(selA)
ECY: ECSE_3868
ECL: EcolC_0122
ECK: EC55989_4049(selA)
ECQ: ECED1_4277(selA)
ECR: ECIAI1_3063 ECIAI1_3759(selA)
ECT: ECIAI39_4109(selA)
ECZ: ECS88_4008(selA)
EUM: ECUMN_4106(selA)
ELF: LF82_2110(selA)
EBL: B21_03397(selA)
EBD: ECBD_0139
EBR: ECB_03446(selA)
EOH: ECO103_4643(selA)
EOI: ECO111_3678 ECO111_4411(selA)
EOJ: ECO26_4029 ECO26_5010(selA)
EFE: EFER_3585(selA)
STY: STY4017 STY4113(selA) STY4785
STT: t3750 t3836(selA) t4480
SPT: SPA3534(selA) SPA3618 SPA4246
SEK: SSPA3300 SSPA3380 SSPA3944
SPQ: SPAB_04576 SPAB_04684 SPAB_05596
SEI: SPC_3763(selA) SPC_3847 SPC_4578
SEC: SC3607(selA) SC4301(mlr)
SEH: SeHA_C4006(selA) SeHA_C4098 SeHA_C4847
SEE: SNSL254_A3961(selA) SNSL254_A4047 SNSL254_A4792
SEW: SeSA_A3883(selA) SeSA_A3975 SeSA_A4697
SEA: SeAg_B3897(selA) SeAg_B3993 SeAg_B4728
SED: SeD_A4068(selA) SeD_A4161 SeD_A4826
SEG: SG3660 SG3747(selA) SG4271
SET: SEN3505(selA) SEN3590 SEN4195
SES: SARI_03965
STM: STM3683(selA) STM3768 STM4446
YPE: YPO4054(selA)
YPK: y4074(selA)
YPM: YP_3966(selA)
YPA: YPA_3031
YPN: YPN_3701
YPG: YpAngola_A3766(selA)
YPP: YPDSF_0039
YPS: YPTB3931(selA)
YPI: YpsIP31758_4115(selA)
YPY: YPK_0042
YPB: YPTS_4154
YEN: YE3780 YE4131(fdhA)
SFL: SF3629(selA)
SFX: S4139(selA)
SFV: SFV_3942(selA)
SSN: SSON_3817(selA)
SBO: SBO_3591(selA)
SBC: SbBS512_E4006(selA)
SDY: SDY_4212(selA)
PWA: Pecwa_0918
ETA: ETA_29260
PLU: plu4897(selA)
PAY: PAU_04385(selA)
ENT: Ent638_0140 Ent638_0430
ESA: ESA_00254 ESA_03875
CTU: Ctu_01310(selA)
KPN: KPN_03939(selA) KPN_04639
KPE: KPK_0157(selA) KPK_5024
KPU: KP1_0515 KP1_5287(selA)
CKO: CKO_03585 CKO_05047 CKO_05128
SPE: Spro_0090 Spro_4375
PMR: PMI3106(selA)
EIC: NT01EI_3472
ETR: ETAE_3120(selA)
DDA: Dd703_3153
HIN: HI0708(selA)
HIT: NTHI0835(selA)
HIP: CGSHiEE_08600
HDU: HD1994(selA)
HAP: HAPS_1589(selA)
PMU: PM1768(selA)
MSU: MS2338(selA)
APL: APL_1562(selA)
APJ: APJL_1590(selA)
APA: APP7_1624
ASU: Asuc_0441
AAP: NT05HA_1972
AAT: D11S_0743
SML: Smlt3849(selA)
SMT: Smal_3265
VFI: VF_2508
VFM: VFMJ11_2634
VSA: VSAL_I0105
PPR: PBPRB1540
PAE: PA4808(selA)
PAU: PA14_63540(selA)
PAP: PSPA7_5527(selA)
PAG: PLES_51921(selA)
PPU: PP_0493(selA)
PPF: Pput_0527
PPG: PputGB1_0536
PPW: PputW619_0548
PFO: Pfl01_2706
PEN: PSEEN0568(selA)
PSA: PST_0162(selA)
SON: SO_0105(selA)
SBM: Shew185_0104
SBN: Sbal195_0109
SBP: Sbal223_0108
SPL: Spea_0442
SHE: Shewmr4_0106
SHM: Shewmr7_0101
SHN: Shewana3_0106
SHL: Shal_0497
AHA: AHA_2508(selA) AHA_3916
ASA: ASA_0322(selA) ASA_1806(selA)
LHK: LHK_00759
BMA: BMAA1678.1(selA)
BMV: BMASAVP1_1696(selA)
BML: BMA10229_1903(selA)
BMN: BMA10247_A0575(selA)
BPS: BPSS1663(selA)
BPM: BURPS1710b_A0726(selA)
BPL: BURPS1106A_A2255(selA)
BPD: BURPS668_A2392(selA)
BTE: BTH_II0711(selA)
BVI: Bcep1808_4490
BUR: Bcep18194_B2096
BCH: Bcen2424_3988
BCM: Bcenmc03_3540
BCJ: BCAM1022(selA)
BAM: Bamb_3381
BAC: BamMC406_3883
BMU: Bmul_4593
BMJ: BMULJ_03917(selA)
BXE: Bxe_B2549
BPH: Bphy_4522
BPY: Bphyt_2704 Bphyt_6556
BGL: bglu_2g08680
BAV: BAV3147(selA)
RFR: Rfer_0940
DAC: Daci_3486
CTT: CtCNB1_2125
DAR: Daro_1814
HPY: HP1513
HPJ: jhp1406(selA)
HPA: HPAG1_1399
HPS: HPSH_07770
HPG: HPG27_1437
HPP: HPP12_1491(selA)
HPB: HELPY_1486(selA)
HHE: HH0740(selA)
HAC: Hac_0070(selA)
WSU: WS0840(selA)
TDN: Suden_0831
CJE: Cj1378(selA)
CJR: CJE1569(selA)
CJJ: CJJ81176_1380(selA)
CJU: C8J_1296(selA)
CJD: JJD26997_0273(selA)
CFF: CFF8240_1546(selA)
CCV: CCV52592_0540(selA)
CHA: CHAB381_0765(selA)
CCO: CCC13826_0755(selA)
CLA: Cla_1286(selA)
ABU: Abu_1524(selA)
SDL: Sdel_2082
NAM: NAMH_1324(selA)
GSU: GSU3369(selA)
GME: Gmet_0061
GUR: Gura_4162
GLO: Glov_0873
GBM: Gbem_3796
GEO: Geob_0561
GEM: GM21_3879
PCA: Pcar_0819(selA)
DVU: DVU2883(selA)
DVL: Dvul_0482
DVM: DvMF_1311
DDE: Dde_3059
DDS: Ddes_1740
DMA: DMR_30540(selA)
DSA: Desal_2187
LIP: LI0132(selA)
DBA: Dbac_0506
DRT: Dret_0760
DPS: DP1691
DOL: Dole_3060
DAL: Dalk_4347
DAT: HRM2_35900(selA)
ADE: Adeh_0412
ACP: A2cp1_0441
AFW: Anae109_4157
ANK: AnaeK_0440
MXA: MXAN_3346(selA)
HOH: Hoch_2208
SAT: SYN_01801
SFU: Sfum_3477
MLO: mlr3804
SME: SMa0011(selA)
ATU: Atu3263(selA)
ATC: AGR_L_3109
ARA: Arad_7947(selA)
AVI: Avi_5094(selA)
RET: RHE_PE00344(selA)
REC: RHECIAT_PA0000274(selA)
RLE: pRL110458
RLT: Rleg2_5759
RLG: Rleg_6666
OAN: Oant_2867 Oant_2990
OCA: OCAR_5163(selA)
XAU: Xaut_0658
AZC: AZC_1155
MRD: Mrad2831_5143
MET: M446_2152
MSL: Msil_3334
PDE: Pden_0301
HNE: HNE_2489(selA)
BAN: BA5099
BAR: GBAA5099
BAA: BA_5518
BAT: BAS4739
BAH: BAMEG_5134
BAI: BAA_5112
BCE: BC4845
BCA: BCE_5002
BCZ: BCZK4598(selA)
BCR: BCAH187_A4987
BCB: BCB4264_A4974
BCU: BCAH820_4959
BCG: BCG9842_B0261
BCQ: BCQ_4663(selA)
BCX: BCA_4982
BTK: BT9727_4579(selA)
BTL: BALH_4412(selA)
BWE: BcerKBAB4_4688
BCL: ABC1413
OIH: OB3204
GYM: GYMC10_5787
BBE: BBR47_31640
PJD: Pjdr2_0940
LPL: lp_0251(selA)
LCA: LSEI_2712
LCB: LCABL_28920(selA)
LRH: LGG_02708(selA)
LRL: LC705_02711(selA)
EFA: EF0838
CPE: CPE2117(selA)
CPF: CPF_2373(selA)
CPR: CPR_2085(selA)
CDF: CD2495(fdhA) CD3642
CDC: CD196_2340(fdhA) CD196_3455
CDL: CDR20291_2387(fdhA) CDR20291_3501
CBO: CBO2976(fdhA)
CBA: CLB_3001(selA)
CBH: CLC_2873(selA)
CBY: CLM_3371(selA)
CBL: CLK_2360(selA)
CBB: CLD_1568(selA)
CBI: CLJ_B3233(selA)
CBF: CLI_3030(selA)
AMT: Amet_2323
AOE: Clos_1736
STH: STH2591
SWO: Swol_2561
DSY: DSY3097(selA)
DHD: Dhaf_4267
DRM: Dred_2186
DAE: Dtox_1646
PTH: PTH_1428(selA)
DAU: Daud_1093
HMO: HM1_2507(selA)
FMA: FMG_0433
TTE: TTE1872(selA)
CHY: CHY_1803(selA)
MTA: Moth_2504
ADG: Adeg_0672
CPO: COPRO5265_0230(selA)
NTH: Nther_1162
MPA: MAP0365c
MAV: MAV_0418(selA)
MSM: MSMEG_1850(selA)
MMC: Mmcs_5215
MKM: Mkms_5303
MJL: Mjls_5595
MMI: MMAR_5190(selA)
CAR: cauri_0967(selA)
GBR: Gbro_3579
KRH: KRH_07830(selA)
BFA: Bfae_09650
KSE: Ksed_04250
SRO: Sros_3738
FRA: Francci3_0439
FRE: Franean1_6183
FAL: FRAAL0930(selA)
NML: Namu_5281
KRA: Krad_1608
SEN: SACE_3552
SVI: Svir_16930
STP: Strop_0584 Strop_0594
CAI: Caci_5689
RXY: Rxyl_1983
CCU: Ccur_11390
SHI: Shel_25310
ELE: Elen_1692
TDE: TDE2477(selA)
BHY: BHWA1_00360
ABA: Acid345_4521
SUS: Acid_3675
DFE: Dfer_2440
CPI: Cpin_6463
STR: Sterm_0676
RBA: RB1352
TAI: Taci_0768
CAU: Caur_1021
CHL: Chy400_1118
HAU: Haur_2965
TRO: trd_0422(selA) trd_1134
STI: Sthe_0695
AAE: aq_1031(selA)
TYE: THEYE_A0538(selA)
TTR: Tter_0812
MJA: MJ0158
MFE: Mefer_0198
MVU: Metvu_1650
MMP: MMP0002
MMQ: MmarC5_1682
MMX: MmarC6_0947
MMZ: MmarC7_0999
MAE: Maeo_1169
MVN: Mevan_1219
MTH: MTH1914
MST: Msp_0916
MSI: Msm_0767
MKA: MK0620(selA)
HMU: Hmuk_0099
TAC: Ta0673
CMA: Cmaq_1144
Taxonomy
Structures PDB: 3HL2  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:2007585]
Forchhammer K, Bock A.
Selenocysteine synthase from Escherichia coli. Analysis of the
reaction sequence.
J. Biol. Chem. 266 (1991) 6324-8.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 2.9.1.1
IUBMB Enzyme Nomenclature: 2.9.1.1
ExPASy - ENZYME nomenclature database: 2.9.1.1
BRENDA, the Enzyme Database: 2.9.1.1
CAS: 183869-06-9
DBGET integrated database retrieval system