KEGG   ENZYME: 3.1.1.14Help
Entry
EC 3.1.1.14                 Enzyme                                 

Name
chlorophyllase;
CLH;
Chlase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
chlorophyll chlorophyllidohydrolase
Reaction(IUBMB)
chlorophyll + H2O = phytol + chlorophyllide
Reaction(KEGG)
(other) R05618 R09068
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Substrate
chlorophyll [CPD:C01793];
H2O [CPD:C00001]
Product
phytol [CPD:C01389];
chlorophyllide [CPD:C02139]
Comment
Chlorophyllase has been found in higher plants, diatoms, and in the green algae Chlorella [3]. This enzyme forms part of the chlorophyll degradation pathway and is thought to take part in de-greening processes such as fruit ripening, leaf senescence and flowering, as well as in the turnover and homeostasis of chlorophyll [4]. This enzyme acts preferentially on chlorophyll a but will also accept chlorophyll b and pheophytins as substrates [5]. Ethylene and methyl jasmonate, which are known to accelerate senescence in many species, can enhance the activity of the hormone-inducible form of this enzyme [5].
History
EC 3.1.1.14 created 1961, modified 2007
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K08099  
chlorophyllase
Genes
BFO: 
LGI: 
ATH: 
AT1G19670(CLH1) AT5G43860(CLH2)
ALY: 
CRB: 
EUS: 
BRP: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0005s23590g(POPTRDRAFT_1079153) POPTR_0008s15700g(POPTRDRAFT_564875) POPTR_0010s09240g(POPTRDRAFT_884079) POPTR_0284s00200g
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os02t0286700-00(Os02g0286700) Os10t0419600-00(Os10g0419600)
OBR: 
BDI: 
SBI: 
SORBI_01g021520(SORBIDRAFT_01g021520) SORBI_02g012201(SORBIDRAFT_02g012201) SORBI_02g012300(SORBIDRAFT_02g012300) SORBI_07g024090(SORBIDRAFT_07g024090)
ZMA: 
SITA: 
PDA: 
MUS: 
ATR: 
s00002p00270990(AMTR_s00002p00270990) s00002p00271040(AMTR_s00002p00271040)
SMO: 
PPP: 
 » show all
Taxonomy
Reference
1  [PMID:13715233]
  Authors
HOLDEN M.
  Title
The breakdown of chlorophyll by chlorophyllase.
  Journal
Biochem. J. 78 (1961) 359-64.
Reference
2  [PMID:13756631]
  Authors
KLEIN AO, VISHNIAC W.
  Title
Activity and partial purification of chlorophyllase in aqueous systems.
  Journal
J. Biol. Chem. 236 (1961) 2544-7.
Reference
3  [PMID:10611389]
  Authors
Tsuchiya T, Ohta H, Okawa K, Iwamatsu A, Shimada H, Masuda T, Takamiya K.
  Title
Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 15362-7.
  Sequence
Reference
4  [PMID:16610227]
  Authors
Okazawa A, Tango L, Itoh Y, Fukusaki E, Kobayashi A.
  Title
Characterization and subcellular localization of chlorophyllase from Ginkgo biloba.
  Journal
Z. Naturforsch. [C]. 61 (2006) 111-7.
Reference
5  [PMID:16669755]
  Authors
Hortensteiner S.
  Title
Chlorophyll degradation during senescence.
  Journal
Annu. Rev. Plant. Biol. 57 (2006) 55-77.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9025-96-1

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