| Entry |
|
|---|
| Name |
2-pyrone-4,6-dicarboxylate lactonase |
|---|
| Class |
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
 |
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| Sysname |
2-pyrone-4,6-dicarboxylate lactonohydrolase |
|---|
| Reaction(IUBMB) |
2-pyrone-4,6-dicarboxylate + H2O =
4-carboxy-2-hydroxyhexa-2,4-dienedioate [RN:R04277] |
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| Reaction(KEGG) |
R04277
 |
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| Substrate |
2-pyrone-4,6-dicarboxylate [CPD:C03671];
H2O [CPD:C00001] |
|---|
| Product |
4-carboxy-2-hydroxyhexa-2,4-dienedioate [CPD:C04451] |
|---|
| Comment |
The product isomerizes to 4-oxalmesaconate. |
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| Pathway |
PATH: ec00362 Benzoate degradation via hydroxylation |
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| Orthology |
KO: K10221 2-pyrone-4,6-dicarboxylate lactonase |
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| Genes |
PAT: Patl_3887
RFR: Rfer_0332
POL: Bpro_4322
PNA: Pnap_2029
VEI: Veis_0169
AZO: azo2539(ligI)
RLE: pRL120277(ligI)
BRA: BRADO2340(ligI)
BBT: BBta_2700(ligI)
RPA: RPA4700(ligI)
RPB: RPB_0874
RPD: RPD_0984
RPE: RPE_0749
MAG: amb0254
ART: Arth_4374
 |
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| Structures |
PDB: 2QAH |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:7142106]
Kersten PJ, Dagley S, Whittaker JW, Arciero DM, Lipscomb JD.
2-pyrone-4,6-dicarboxylic acid, a catabolite of gallic acids in
Pseudomonas species.
J. Bacteriol. 152 (1982) 1154-62.
Pseudomonas testosteroni |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6841353]
Maruyama K.
Purification and properties of 2-pyrone-4,6-dicarboxylate hydrolase.
J. Biochem. (Tokyo). 93 (1983) 557-65.
Pseudomonas ochraceae |
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| Other DBs |
ExplorEnz - The Enzyme Database: 3.1.1.57
IUBMB Enzyme Nomenclature: 3.1.1.57
ExPASy - ENZYME nomenclature database: 3.1.1.57
BRENDA, the Enzyme Database: 3.1.1.57
CAS: 84177-55-9 |
|---|
