KEGG   ENZYME: 3.1.1.63Help
Entry
EC 3.1.1.63                 Enzyme                                 

Name 11-cis-retinyl-palmitate hydrolase;
11-cis-retinol palmitate esterase;
RPH
Class Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname 11-cis-retinyl-palmitate acylhydrolase
Reaction(IUBMB) 11-cis-retinyl palmitate + H2O = 11-cis-retinol + palmitate
[RN:R03049]
Reaction(KEGG) R03049
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Substrate 11-cis-retinyl palmitate [CPD:C03455];
H2O [CPD:C00001]
Product 11-cis-retinol [CPD:C00899];
palmitate [CPD:C00249]
Effector Bile salt [CPD:C01558]
Comment Activated by bile salts.
Pathway PATH: ec00830  Retinol metabolism
Reference
  Authors
  Title

  Journal
  Organism
1  [PMID:3793734]
Blaner WS, Das SR, Gouras P, Flood MT.
Hydrolysis of 11-cis- and all-trans-retinyl palmitate by homogenates
of human retinal epithelial cells.
J. Biol. Chem. 262 (1987) 53-8.
Homo sapiens [GN:hsa]
Reference
  Authors
  Title

  Journal
  Organism
2  [PMID:6743673]
Blaner WS, Prystowsky JH, Smith JE, Goodman DS.
Rat liver retinyl palmitate hydrolase activity. Relationship to
cholesteryl oleate and triolein hydrolase activities.
Biochim. Biophys. Acta. 794 (1984) 419-27.
Rattus norvegicus [GN:rno]
Other DBs ExplorEnz - The Enzyme Database: 3.1.1.63
IUBMB Enzyme Nomenclature: 3.1.1.63
ExPASy - ENZYME nomenclature database: 3.1.1.63
BRENDA, the Enzyme Database: 3.1.1.63
CAS: 106389-23-5

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