| Entry |
|
| Name |
11-cis-retinyl-palmitate hydrolase;
11-cis-retinol palmitate esterase;
RPH |
| Class |
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
 |
| Sysname |
11-cis-retinyl-palmitate acylhydrolase |
| Reaction(IUBMB) |
11-cis-retinyl palmitate + H2O = 11-cis-retinol + palmitate
[RN:R03049] |
| Reaction(KEGG) |
R03049
 |
| Substrate |
11-cis-retinyl palmitate [CPD:C03455];
H2O [CPD:C00001] |
| Product |
11-cis-retinol [CPD:C00899];
palmitate [CPD:C00249] |
| Effector |
Bile salt [CPD:C01558] |
| Comment |
Activated by bile salts. |
| Pathway |
PATH: ec00830 Retinol metabolism |
Reference Authors Title
Journal Organism
|
1 [PMID:3793734]
Blaner WS, Das SR, Gouras P, Flood MT.
Hydrolysis of 11-cis- and all-trans-retinyl palmitate by homogenates
of human retinal epithelial cells.
J. Biol. Chem. 262 (1987) 53-8.
Homo sapiens [GN:hsa] |
Reference Authors Title
Journal Organism
|
2 [PMID:6743673]
Blaner WS, Prystowsky JH, Smith JE, Goodman DS.
Rat liver retinyl palmitate hydrolase activity. Relationship to
cholesteryl oleate and triolein hydrolase activities.
Biochim. Biophys. Acta. 794 (1984) 419-27.
Rattus norvegicus [GN:rno] |
| Other DBs |
ExplorEnz - The Enzyme Database: 3.1.1.63
IUBMB Enzyme Nomenclature: 3.1.1.63
ExPASy - ENZYME nomenclature database: 3.1.1.63
BRENDA, the Enzyme Database: 3.1.1.63
CAS: 106389-23-5 |