KEGG   ENZYME: 3.1.1.74Help
Entry
EC 3.1.1.74                 Enzyme                                 
Name
cutinase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
cutin hydrolase
Reaction(IUBMB)
cutin + H2O = cutin monomers [RN:R05793]
Reaction(KEGG)
Substrate
cutin [CPD:C07299];
H2O [CPD:C00001]
Product
cutin monomer [CPD:C07300]
Comment
Cutin, a polymeric structural component of plant cuticles, is a polymer of hydroxy fatty acids that are usually C16 or C18 and contain up to three hydroxy groups. The enzyme from several fungal sources also hydrolyses the p-nitrophenyl esters of hexadecanoic acid. It is however inactive towards several esters that are substrates for non-specific esterases.
Orthology
K08095  
cutinase
Genes
MGR: 
ANI: 
NFI: 
AFM: 
AOR: 
AOR_1_1142054(AO090011000665)
ANG: 
ANI_1_1504094(An11g00110)
AFV: 
PCS: 
PIF: 
MTU: 
Rv1984c(cfp21) Rv2301(cut2) Rv3451(cut3)
MTC: 
MT2037 MT2358 MT3557
MRA: 
MRA_1996(cfp21) MRA_2318(cut2) MRA_3492(cut3)
MTF: 
TBFG_12015 TBFG_12324 TBFG_13488
MTB: 
TBMG_01682 TBMG_02005 TBMG_03499
MBO: 
Mb2006c(cfp21) Mb2323(cut2) Mb3481(cut3)
MBB: 
BCG_2317(cut2) BCG_3517(cut3)
MBT: 
JTY_1995(cfp21) JTY_2311(cut2) JTY_3517(cut3)
MPA: 
MAP1662c MAP1680c MAP4237c
MAV: 
MAV_2741 MAV_2759 MAV_2961 MAV_4283 MAV_4394 MAV_4396
MSM: 
MSMEG_1526 MSMEG_1528 MSMEG_2474 MSMEG_4465
MUL: 
MUL_0856(cut3)
MVA: 
Mvan_0371 Mvan_1439 Mvan_1440 Mvan_1441 Mvan_1924 Mvan_3105 Mvan_3344 Mvan_5804
MGI: 
Mflv_3373 Mflv_3552 Mflv_4432 Mflv_4439 Mflv_4965 Mflv_4966 Mflv_4967
MSP: 
Mspyr1_27040 Mspyr1_28940 Mspyr1_38320 Mspyr1_43820 Mspyr1_43830 Mspyr1_43840
MAB: 
MAB_3763 MAB_3766 MAB_3809c
MMC: 
Mmcs_1116 Mmcs_1117 Mmcs_5300
MKM: 
Mkms_1133 Mkms_1134 Mkms_5389
MJL: 
Mjls_1145 Mjls_1146 Mjls_1873 Mjls_5679
MMI: 
MMAR_1098(cut3) MMAR_2908 MMAR_2934(cfp21)
RHA: 
RHA1_ro00629
GBR: 
Gbro_4300
SRT: 
Srot_0144
CFL: 
Cfla_3117
TCU: 
Tcur_1514 Tcur_1519
KRA: 
Krad_4111
 » show all
Taxonomy
Reference
1  [PMID:9281862]
  Authors
Garcia-Lepe R, Nuero OM, Reyes F, Santamaria F.
  Title
Lipases in autolysed cultures of filamentous fungi.
  Journal
Lett. Appl. Microbiol. 25 (1997) 127-30.
  Organism
Aspergillus nidulans [GN:ani], Fusarium decemcellulare, Fusarium moniliforme, Fusarium oxysporum, Fusarium semitectum
Reference
2  [PMID:1156575]
  Authors
Purdy RE, Kolattukudy PE.
  Title
Hydrolysis of plant cuticle by plant pathogens. Purification, amino acid composition, and molecular weight of two isozymes of cutinase and a nonspecific esterase from Fusarium solani f. pisi.
  Journal
Biochemistry. 14 (1975) 2824-31.
  Organism
Fusarium solani
Reference
3  [PMID:239740]
  Authors
Purdy RE, Kolattukudy PE.
  Title
Hydrolysis of plant cuticle by plant pathogens. Properties of cutinase I, cutinase II, and a nonspecific esterase isolated from Fusarium solani pisi.
  Journal
Biochemistry. 14 (1975) 2832-40.
  Organism
Fusarium solani
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
51377-41-4
DBGET integrated database retrieval system