KEGG   ENZYME: 3.1.1.8Help
Entry
EC 3.1.1.8                  Enzyme                                 

Name
cholinesterase;
pseudocholinesterase;
butyrylcholine esterase;
non-specific cholinesterase;
choline esterase II (unspecific);
benzoylcholinesterase;
choline esterase;
butyrylcholinesterase;
propionylcholinesterase;
BtChoEase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
acylcholine acylhydrolase
Reaction(IUBMB)
an acylcholine + H2O = choline + a carboxylate [RN:R01029]
Reaction(KEGG)
Substrate
acylcholine [CPD:C01777];
H2O [CPD:C00001]
Product
choline [CPD:C00114];
carboxylate [CPD:C00060]
Comment
Acts on a variety of choline esters and a few other compounds.
History
EC 3.1.1.8 created 1961
Orthology
K01050  
cholinesterase
Genes
HSA: 
590(BCHE)
PTR: 
460830(BCHE)
PPS: 
100972372(BCHE)
GGO: 
101135975(BCHE)
PON: 
100174585(BCHE)
MCC: 
700484(BCHE)
MCF: 
102130167(BCHE)
MMU: 
12038(Bche)
RNO: 
65036(Bche)
CGE: 
100767789(Bche)
HGL: 
101712877(Bche)
TUP: 
102496968(BCHE)
CFA: 
488143(BCHE)
AML: 
FCA: 
493960(BCHE)
PTG: 
BTA: 
534616(BCHE)
BOM: 
102267863(BCHE)
PHD: 
102328336(BCHE)
CHX: 
102187168(BCHE)
OAS: 
101102112(BCHE)
SSC: 
100624138(BCHE)
CFR: 
102523324(BCHE)
BACU: 
103011235(BCHE)
LVE: 
103076485(BCHE)
ECB: 
100033901(BCHE)
MYB: 
MYD: 
102753302(BCHE)
PALE: 
102883546(BCHE)
MDO: 
100618084(BCHE)
SHR: 
100930262(BCHE)
OAA: 
100074368(BCHE)
GGA: 
395358(BCHE)
TGU: 
100229708(BCHE)
FAB: 
101808546(BCHE)
PHI: 
102106247(BCHE)
APLA: 
FPG: 
101918906(BCHE)
FCH: 
102056322(BCHE)
CLV: 
102095857(BCHE)
ASN: 
102386904(BCHE)
AMJ: 
PSS: 
102451430(BCHE)
CMY: 
102946073(BCHE)
ACS: 
PBI: 
XTR: 
TRU: 
MZE: 
OLA: 
XMA: 
CMK: 
BFO: 
DPO: 
DPE: 
BMOR: 
API: 
PHU: 
ISC: 
BMY: 
LOA: 
TSP: 
NVE: 
AFM: 
ADL: 
DPP: 
EHX: 
NGR: 
 » show all
Taxonomy
Reference
1
  Authors
Augustinsson, K.-B.
  Title
Cholinesterases. A study in comparative enzymology.
  Journal
Acta Physiol. Scand. 15, Suppl. 2 (1948)
Reference
2  [PMID:13638253]
  Authors
AUGUSTINSSON KB, OLSSON B.
  Title
Esterases in the milk and blood plasma of swine. I. Substrate specificity and electrophoresis studies.
  Journal
Biochem. J. 71 (1959) 477-84.
  Organism
Sus scofa
Reference
3  [PMID:13032058]
  Authors
KOELLE GB.
  Title
Cholinesterases of the tissues and sera of rabbits.
  Journal
Biochem. J. 53 (1953) 217-26.
  Organism
Oryctolagus cuniculus
Reference
4  [PMID:14885021]
  Authors
NACHMANSOHN D, WILSON IB.
  Title
The enzymic hydrolysis and synthesis of acetylcholine.
  Journal
Adv. Enzymol. Relat. Subj. Biochem. 12 (1951) 259-339.
Reference
5
  Authors
Sawyer, C.H.
  Title
Hydrolysis of choline esters by liver.
  Journal
Science 101 (1945) 385-386.
Reference
6  [PMID:16747753]
  Authors
Strelitz F.
  Title
Studies on cholinesterase: 4. Purification of pseudo-cholinesterase from horse serum.
  Journal
Biochem. J. 38 (1944) 86-8.
  Organism
Equus caballus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9001-08-5

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