KEGG   ENZYME: 3.1.11.3Help
Entry
EC 3.1.11.3                 Enzyme                                 

Name
exodeoxyribonuclease (lambda-induced);
lambda exonuclease;
phage lambda-induced exonuclease;
Escherichia coli exonuclease IV;
E. coli exonuclease IV;
exodeoxyribonuclease IV;
exonuclease IV
Class
Hydrolases;
Acting on ester bonds;
Exodeoxyribonucleases producing 5'-phosphomonoesters
BRITE hierarchy
Reaction(IUBMB)
Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates
Comment
Preference for double-stranded DNA. Does not attack single-strand breaks.
History
EC 3.1.11.3 created 1972 as EC 3.1.4.28, transferred 1978 to EC 3.1.11.3
Orthology
K01143  
exodeoxyribonuclease (lambda-induced)
Genes
ECI: 
ECV: 
STY: 
STY1016(exo)
STT: 
t1924(exo)
ENT: 
HAR: 
BTR: 
Btr_0376(exo) Btr_0425(exo) Btr_0563(exo) Btr_0980(exo) Btr_0984(exo) Btr_2304(exo)
Taxonomy
Reference
1  [PMID:5256235]
  Authors
Lindahl T, Gally JA, Edelman GM.
  Title
Deoxyribonuclease IV: a new exonuclease from mammalian tissues.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 62 (1969) 597-603.
  Organism
Oryctolagus cuniculus
Reference
2  [PMID:6017737]
  Authors
Little JW.
  Title
An exonuclease induced by bacteriophage lambda. II. Nature of the enzymatic reaction.
  Journal
J. Biol. Chem. 242 (1967) 679-86.
  Organism
Escherichia coli
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37367-70-7

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