KEGG   ENZYME: 3.1.21.4Help
Entry
EC 3.1.21.4                 Enzyme                                 
Name
type II site-specific deoxyribonuclease;
type II restriction enzyme
Class
Hydrolases;
Acting on ester bonds;
Endodeoxyribonucleases producing 5'-phosphomonoesters
BRITE hierarchy
Reaction(IUBMB)
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates
Comment
This is a large group of enzymes which, together with those now listed as EC 3.1.21.3 (type 1 site-specific deoxyribonuclease) and EC 3.1.21.5.
Orthology
K01155  
type II restriction enzyme
Genes
ECR: 
SPE: 
HIN: 
HI0512(hindIIR) HI1040(ureF) HI1393(hindIIIR)
HIT: 
NTHI1786(haeIIR)
PAR: 
Psyc_0143(dpnC)
PCR: 
PRW: 
ABM: 
MCT: 
PAT: 
NMA: 
NMA1499
NME: 
NMB0726 NMB1032(nlaIVR) NMB1289 NMB1896(dpnC)
NMC: 
NMC0680
NMN: 
NMCC_0324(drg)
VEI: 
Veis_0524 Veis_3517
HPY: 
HP0091 HP1209 HP1366
HPJ: 
jhp1442
HPA: 
HPAG1_1150 HPAG1_1151
HPS: 
HPSH_07070
HPG: 
HPG27_84
HPP: 
HPP12_0094 HPP12_1174
HAC: 
Hac_0188 Hac_0305
TDN: 
Suden_0128
CHA: 
CHAB381_1228
ANT: 
Arnit_2984
SDL: 
Sdel_1531
DOL: 
Dole_3089
SFU: 
Sfum_2533
SAD: 
SAAV_0819
SPN: 
SP_1221 SP_1222 SP_1850
SPD: 
SPD_1079 SPD_1080 SPD_1631
SPR: 
spr1101(spnII-interrupted-C) spr1102(spnII-interrupted-N) spr1285(spnIR-truncation) spr1286(spnIR-truncation) spr1665(dpnC)
SPW: 
SPCG_1824(dpnC)
SPX: 
SPG_1733(dpnB)
SPV: 
SPH_1964
SNM: 
SP70585_1903
SJJ: 
SPJ_1755
SPP: 
SPP_1848
SNT: 
SPT_1767
SNC: 
HMPREF0837_12073(dpnC)
SNB: 
SP670_1923
SNP: 
SPAP_1844
SMU: 
SMU_506
SMC: 
SmuNN2025_1466
SSA: 
SSA_1716
SMB: 
smi_0526
CTH: 
Cthe_1512
EEL: 
EUBELI_01767
RAL: 
Rumal_0668
TEX: 
Teth514_0459
THX: 
Thet_0507
TPD: 
Teth39_1776
TIT: 
Thit_0486
CHY: 
CHY_2211
CPO: 
COPRO5265_1446(hsdR)
SSG: 
Selsp_0626
MED: 
MELS_0976
MMY: 
MSC_0185 MSC_0215(sau96I-like)
MMO: 
MMOB3440(dpnII)
MAL: 
MAGa2710
MCD: 
MCRO_0752
ACL: 
ACL_1082(dpnII)
STP: 
Strop_0105
MCU: 
HMPREF0573_11642(dpnB)
SUS: 
Acid_1688
BFR: 
BF2023
BFS: 
BF2077
BVU: 
BVU_3992
RSI: 
Runsl_4415
MTT: 
Ftrac_0428
FPS: 
FP2273(hpaIIR)
RAN: 
Riean_1818
AMU: 
Amuc_1564
TLI: 
Tlie_0307
ANA: 
all3631(avaIR)
PMM: 
PMM0384(spnII-interrupted-C)
TER: 
Tery_4526
CCH: 
Cag_0333
CPH: 
Cpha266_1502 Cpha266_1908 Cpha266_2523
DEB: 
DehaBAV1_0080
DLY: 
Dehly_0468
ATM: 
ANT_07640
DTE: 
Dester_0101
TME: 
Tmel_0307
DTH: 
DICTH_1799
CNI: 
Calni_0428
MJA: 
MJ_0600
MOK: 
Metok_0256
MMA: 
MM_0156
MST: 
Msp_0144
 » show all
Taxonomy
Reference
1  [PMID:2159140]
  Authors
Roberts RJ.
  Title
Restriction enzymes and their isoschizomers.
  Journal
Nucleic. Acids. Res. 18 Suppl (1990) 2331-65.
  Organism
Haemophilus influenzae
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9075-08-5
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