| Entry |
|
|---|
| Name |
streptomycin-6-phosphatase;
streptomycin 6-phosphate phosphatase;
streptomycin 6-phosphate phosphohydrolase;
streptomycin-6-P phosphohydrolase |
|---|
| Class |
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
 |
|---|
| Sysname |
streptomycin-6-phosphate phosphohydrolase |
|---|
| Reaction(IUBMB) |
streptomycin 6-phosphate + H2O = streptomycin + phosphate
[RN:R02228] |
|---|
| Reaction(KEGG) |
R02228
 |
|---|
| Substrate |
streptomycin 6-phosphate [CPD:C01138];
H2O [CPD:C00001] |
|---|
| Product |
streptomycin [CPD:C00413];
phosphate [CPD:C00009] |
|---|
| Comment |
Also acts on dihydrostreptomycin 3'alpha,6-bisphosphate and
streptidine 6-phosphate. |
|---|
| Pathway |
PATH: ec00521 Streptomycin biosynthesis |
|---|
| Orthology |
KO: K04342 streptomycin-6-phosphatase |
|---|
| Genes |
SGR: SGR_5938(strK)
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4121457]
Walker JB, Skorvaga M.
Streptomycin biosynthesis and metabolism. Phosphate transfer from
dihydrostreptomycin 6-phosphate to inosamines, streptamine, and
2-deoxystreptamine.
J. Biol. Chem. 248 (1973) 2441-6.
Streptomyces bikiniensis |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:4331203]
Walker MS, Walker JB.
Streptomycin biosynthesis. Separation and substrate specificities of
phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and
streptomycin-(streptidino)phosphate.
J. Biol. Chem. 246 (1971) 7034-40.
Streptomyces bikiniensis |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.1.3.39
IUBMB Enzyme Nomenclature: 3.1.3.39
ExPASy - ENZYME nomenclature database: 3.1.3.39
BRENDA, the Enzyme Database: 3.1.3.39
CAS: 9055-33-8 |
|---|
