| Entry |
|
|---|
| Name |
glucuronate-2-sulfatase;
glucurono-2-sulfatase |
|---|
| Class |
Hydrolases;
Acting on ester bonds;
Sulfuric-ester hydrolases
 |
|---|
| Sysname |
polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase |
|---|
| Reaction(IUBMB) |
Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate
residues of chondroitin sulfate, heparin and heparitin sulfate
[RN:R07817] |
|---|
| Reaction(KEGG) |
R07817(G)
 |
|---|
| Comment |
Does not act on iduronate 2-sulfate residues (cf. EC 3.1.6.13
iduronate-2-sulfatase) |
|---|
| Pathway |
PATH: ec00531 Glycosaminoglycan degradation
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4019466]
Shaklee PN, Glaser JH, Conrad HE.
A sulfatase specific for glucuronic acid 2-sulfate residues in
glycosaminoglycans.
J. Biol. Chem. 260 (1985) 9146-9.
Homo sapiens [GN:hsa] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.1.6.18
IUBMB Enzyme Nomenclature: 3.1.6.18
ExPASy - ENZYME nomenclature database: 3.1.6.18
BRENDA, the Enzyme Database: 3.1.6.18
CAS: 98597-45-6 |
|---|
