| Entry |
|
|---|
| Name |
N-acetylgalactosamine-6-sulfatase;
chondroitin sulfatase;
chondroitinase;
galactose-6-sulfate sulfatase;
acetylgalactosamine 6-sulfatase;
N-acetylgalactosamine-6-sulfate sulfatase;
N-acetylgalactosamine 6-sulfatase |
|---|
| Class |
Hydrolases;
Acting on ester bonds;
Sulfuric-ester hydrolases
 |
|---|
| Sysname |
N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase |
|---|
| Reaction(IUBMB) |
Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine
6-sulfate units of chondroitin sulfate and of the D-galactose
6-sulfate units of keratan sulfate [RN:R07806] |
|---|
| Reaction(KEGG) |
R07806(G)
 |
|---|
| Pathway |
PATH: ec00531 Glycosaminoglycan degradation
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K01132 N-acetylgalactosamine-6-sulfatase |
|---|
| Genes |
HSA: 2588(GALNS)
MMU: 50917(Galns)
RNO: 292073(Galns)
CFA: 489661(GALNS)
BTA: 515809(GALNS)
SSC: 397000(GALNS)
ECB: 100051284
MDO: 100026247
OAA: 100089863
GGA: 415848(GALNS)
TGU: 100222785
XLA: 495239
XTR: 100158481
DRE: 791159(galns)
BFO: BRAFLDRAFT_124052 BRAFLDRAFT_99415
CIN: 100177085
SPU: 579130 588014
RBA: RB1456 RB7879(GALNS)
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6939689]
Epstein EH Jr, Leventhal ME.
Steroid sulfatase of human leukocytes and epidermis and the
diagnosis of recessive X-linked ichthyosis.
J. Clin. Invest. 67 (1981) 1257-62.
Homo sapiens [GN:hsa] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6213226]
Glossl J, Kresse H.
Impaired degradation of keratan sulphate by Morquio A fibroblasts.
Biochem. J. 203 (1982) 335-8.
Homo sapiens [GN:hsa] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:7213753]
Lim CT, Horwitz AL.
Purification and properties of human N-acetylgalactosamine-6-sulfate
sulfatase.
Biochim. Biophys. Acta. 657 (1981) 344-55.
Homo sapiens [GN:hsa] |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:6814909]
Sorensen SH, Noren O, Sjostrom H, Danielsen EM.
Amphiphilic pig intestinal microvillus maltase/glucoamylase.
Structure and specificity.
Eur. J. Biochem. 126 (1982) 559-68.
Sus scofa [GN:ssc] |
|---|
Reference
Authors
Title
Journal
Organism
|
5 [PMID:6809361]
Yutaka T, Okada S, Kato T, Inui K, Yabuuhi H.
Galactose 6-sulfate sulfatase activity in Morquio syndrome.
Clin. Chim. Acta. 122 (1982) 169-80.
shark |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.1.6.4
IUBMB Enzyme Nomenclature: 3.1.6.4
ExPASy - ENZYME nomenclature database: 3.1.6.4
BRENDA, the Enzyme Database: 3.1.6.4
CAS: 9025-60-9 |
|---|
