KEGG   ENZYME: 3.1.6.8Help
Entry
EC 3.1.6.8                  Enzyme                                 

Name
cerebroside-sulfatase;
arylsulfatase A;
cerebroside sulfate sulfatase
Class
Hydrolases;
Acting on ester bonds;
Sulfuric-ester hydrolases
BRITE hierarchy
Sysname
cerebroside-3-sulfate 3-sulfohydrolase
Reaction(IUBMB)
a cerebroside 3-sulfate + H2O = a cerebroside + sulfate [RN:R04856 R06280]
Reaction(KEGG)
Substrate
cerebroside 3-sulfate [CPD:C06125];
H2O [CPD:C00001]
Product
cerebroside [CPD:C02686];
sulfate [CPD:C00059]
Comment
Hydrolyses galactose-3-sulfate residues in a number of lipids. Also hydrolyses ascorbate 2-sulfate and many phenol sulfates.
History
EC 3.1.6.8 created 1972
Pathway
Sphingolipid metabolism
Orthology
K01134  
arylsulfatase A
Genes
HSA: 
410(ARSA)
PTR: 
458946(ARSA)
PPS: 
100978823(ARSA)
GGO: 
101143133(ARSA)
PON: 
100446820(ARSA)
MCC: 
716500(ARSA)
MCF: 
102115714(ARSA)
MMU: 
11883(Arsa)
RNO: 
315222(Arsa)
CGE: 
100754567(Arsa)
HGL: 
101722754(Arsa)
TUP: 
102480471(ARSA)
CFA: 
474457(ARSA)
AML: 
FCA: 
101083690(ARSA)
PTG: 
102953467(ARSA)
BTA: 
505514(ARSA)
BOM: 
102269852(ARSA)
PHD: 
102343796(ARSA)
CHX: 
102188131(ARSA)
SSC: 
396973(AS-A)
CFR: 
102503935(ARSA)
BACU: 
103016839(ARSA)
LVE: 
103072938(ARSA)
ECB: 
100056911(ARSA)
MYB: 
102251510(ARSA)
MYD: 
102765427(ARSA)
PALE: 
102886844(ARSA)
MDO: 
100012344(ARSA)
SHR: 
100930631(ARSA)
OAA: 
GGA: 
426863(ARSA)
MGP: 
FAB: 
101810714(ARSA)
PHI: 
102100828(ARSA)
APLA: 
101795828(ARSA)
FPG: 
FCH: 
CLV: 
102084775(ARSA)
ASN: 
102371342(ARSA)
PSS: 
ACS: 
XLA: 
447252(arsa.1)
XTR: 
DRE: 
541416(arsa)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102357546(ARSA)
SPU: 
AQU: 
EHX: 
RBA: 
RB10116(arsA) RB12325 RB12432 RB409 RB4784(aslA) RB4815 RB6873 RB6956 RB7481(arsA) RB7995(arsA) RB8078(arsA) RB9192(arsA) RB9755(arsA)
HMA: 
 » show all
Taxonomy
Reference
1  [PMID:5829234]
  Authors
Mehl E, Jatzkewitz H.
  Title
[A cerebrosidesulfatase from swine kidney]
  Journal
Hoppe. Seylers. Z. Physiol. Chem. 339 (1964) 260-76.
  Organism
Sus scofa
Reference
2  [PMID:13772]
  Authors
Roy AB.
  Title
Sulphatases, lysosomes and disease.
  Journal
Aust. J. Exp. Biol. Med. Sci. 54 (1976) 111-35.
  Organism
Homo sapiens, Sus scofa
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9068-68-2

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