| Entry |
|
|---|
| Name |
keratan-sulfate endo-1,4-beta-galactosidase;
endo-beta-galactosidase;
keratan sulfate endogalactosidase;
keratanase;
keratan-sulfate 1,4-beta-D-galactanohydrolase |
|---|
| Class |
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl
compounds
 |
|---|
| Sysname |
keratan-sulfate 4-beta-D-galactanohydrolase |
|---|
| Reaction(IUBMB) |
Endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan
sulfate [RN:R07805] |
|---|
| Reaction(KEGG) |
R07805(G)
 |
|---|
| Comment |
Hydrolyses the 1,4-beta-D-galactosyl linkages adjacent to
1,3-alpha-D-N-acetyl-glucosaminyl residues. Also acts on some
non-sulfated oligosaccharides, but only acts on blood group
substances when the 1,2-linked fucosyl residues have been removed
(cf. EC 3.2.1.102 blood-group-substance
endo-1,4-beta-galactosidase). |
|---|
| Pathway |
PATH: ec00531 Glycosaminoglycan degradation
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:135762]
Fukuda MN, Matsumura G.
Endo-beta-galactosidase of Escherichia freundii. Purification and
endoglycosidic action on keratan sulfates, oligosaccharides, and
blood group active glycoprotein.
J. Biol. Chem. 251 (1976) 6218-25.
Escherichia freundii |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.2.1.103
IUBMB Enzyme Nomenclature: 3.2.1.103
ExPASy - ENZYME nomenclature database: 3.2.1.103
BRENDA, the Enzyme Database: 3.2.1.103
CAS: 55072-01-0 |
|---|
