KEGG   ENZYME: 3.2.1.106Help
Entry
EC 3.2.1.106                Enzyme                                 

Name
mannosyl-oligosaccharide glucosidase;
Glc3Man9NAc2 oligosaccharide glucosidase;
trimming glucosidase I
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
mannosyl-oligosaccharide glucohydrolase
Reaction(IUBMB)
Exohydrolysis of the non-reducing terminal glucose residues in the mannosyl-oligosaccharide Glc3Man9GlcNAc2
Reaction(KEGG)
(other) R05979(G)
Show
Comment
Also acts, more slowly, on the corresponding glycolipids and glycopeptides. Involved in the formation of high-mannose and complex glycoproteins.
History
EC 3.2.1.106 created 1984
Pathway
N-Glycan biosynthesis
Metabolic pathways
Orthology
K01228  
mannosyl-oligosaccharide glucosidase
Genes
HSA: 
7841(MOGS)
PTR: 
740472(MOGS)
PPS: 
100989540(MOGS)
GGO: 
101148967(MOGS)
PON: 
100456318(MOGS)
MCC: 
708913(MOGS)
MCF: 
102131903(MOGS)
MMU: 
57377(Mogs)
RNO: 
78947(Gcs1)
CGE: 
100689098(Mogs)
HGL: 
101699668(Mogs)
TUP: 
102469724(MOGS)
CFA: 
483104(MOGS)
AML: 
FCA: 
101086221(MOGS)
PTG: 
102965884(MOGS)
BTA: 
516155(MOGS)
BOM: 
102271661(MOGS)
PHD: 
102337257(MOGS)
CHX: 
102171985(MOGS)
SSC: 
100513204(MOGS)
CFR: 
102503430(MOGS)
BACU: 
102999832(MOGS)
LVE: 
103084054(MOGS)
ECB: 
100069105(MOGS)
MYB: 
102262392(MOGS)
MYD: 
102775421(MOGS)
PALE: 
102887551(MOGS)
MDO: 
100017334(MOGS)
SHR: 
100925812(MOGS)
FAB: 
PHI: 
102101442(MOGS)
FCH: 
ASN: 
102376243(MOGS)
AMJ: 
102576397(MOGS)
CMY: 
102941231(MOGS)
ACS: 
PBI: 
XLA: 
100158418(mogs)
XTR: 
619362(mogs)
DRE: 
567913(mogs)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103172295(mogs)
BFO: 
CIN: 
SPU: 
591837(mogs)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AAG: 
CQU: 
AME: 
411730(GB12872)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CELE_F13H10.4(F13H10.4)
CBR: 
BMY: 
LOA: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
POPTR_0008s17610g(POPTRDRAFT_565044) POPTR_0010s06890g(POPTRDRAFT_821827)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0921200-01(Os01g0921200)
OBR: 
BDI: 
SBI: 
SORBI_03g044090(SORBIDRAFT_03g044090)
SITA: 
ATR: 
s00013p00235370(AMTR_s00013p00235370)
SMO: 
PPP: 
CRE: 
VCN: 
CSL: 
CVR: 
CME: 
GSL: 
CCP: 
SCE: 
YGL027C(CWH41)
AGO: 
ERC: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A01760(NCAS0A01760)
NDI: 
NDAI_0D03690(NDAI0D03690)
TPF: 
TPHA_0K01720(TPHA0K01720)
TBL: 
TBLA_0A08950(TBLA0A08950)
TDL: 
TDEL_0F02570(TDEL0F02570)
KAF: 
KAFR_0F03510(KAFR0F03510)
DHA: 
PIC: 
PGU: 
LEL: 
SPAA: 
CAL: 
CaO19.11899(CWH41) CaO19.4421(CWH41) CaO19.4719(CWH41)
CTP: 
CDU: 
CD36_45640(CWH41)
COT: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_260114(AO090701000141)
ANG: 
ANI_1_240134(An15g01420)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
ZTR: 
PFJ: 
BCOM: 
TML: 
SPO: 
PPL: 
CCI: 
SCM: 
UMA: 
MGL: 
PGR: 
DDI: 
DPP: 
DFA: 
ACAN: 
TGO: 
TET: 
PTM: 
PIF: 
NGD: 
EHX: 
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
NGR: 
 » show all
Taxonomy
Reference
1  [PMID:7358674]
  Authors
Elting JJ, Chen WW, Lennarz WJ.
  Title
Characterization of a glucosidase involved in an initial step in the processing of oligosaccharide chains.
  Journal
J. Biol. Chem. 255 (1980) 2325-31.
  Organism
Rattus norvegicus
Reference
2  [PMID:479161]
  Authors
Grinna LS, Robbins PW.
  Title
Glycoprotein biosynthesis. Rat liver microsomal glucosidases which process oligosaccharides.
  Journal
J. Biol. Chem. 254 (1979) 8814-8.
  Organism
Rattus norvegicus
Reference
3  [PMID:7014569]
  Authors
Kilker RD Jr, Saunier B, Tkacz JS, Herscovics A.
  Title
Partial purification from Saccharomyces cerevisiae of a soluble glucosidase which removes the terminal glucose from the oligosaccharide Glc3Man9GlcNAc2.
  Journal
J. Biol. Chem. 256 (1981) 5299-603.
  Organism
Saccharomyces cerevisiae
Reference
4  [PMID:7358666]
  Authors
Grinna LS, Robbins PW.
  Title
Substrate specificities of rat liver microsomal glucosidases which process glycoproteins.
  Journal
J. Biol. Chem. 255 (1980) 2255-8.
  Organism
Rattus norvegicus
Reference
5  [PMID:7356331]
  Authors
Michael JM, Kornfeld S.
  Title
Partial purification and characterization of the glucosidases involved in the processing of asparagine-linked oligosaccharides.
  Journal
Arch. Biochem. Biophys. 199 (1980) 249-58.
  Organism
Bos taurus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
78413-07-7

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