| Entry |
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| Name |
mannosyl-oligosaccharide glucosidase;
Glc3Man9NAc2 oligosaccharide glucosidase;
trimming glucosidase I
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| Class |
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
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| Sysname |
mannosyl-oligosaccharide glucohydrolase
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| Reaction(IUBMB) |
Exohydrolysis of the non-reducing terminal glucose residues in the mannosyl-oligosaccharide Glc3Man9GlcNAc2
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| Reaction(KEGG) |
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| Comment |
Also acts, more slowly, on the corresponding glycolipids and glycopeptides. Involved in the formation of high-mannose and complex glycoproteins.
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| Pathway |
| N-Glycan biosynthesis | | Metabolic pathways |
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| Orthology |
| mannosyl-oligosaccharide glucosidase |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | ACS: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | CIN: | | SPU: | | DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DSI: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | AAG: | | CQU: | | AME: | | NVI: | | TCA: | | API: | | PHU: | | ISC: | | CEL: | | CBR: | | BMY: | | SMM: | | NVE: | | HMG: | | TAD: | | AQU: | | ATH: | | ALY: | | GMX: | | MTR: | | CSV: | | RCU: | | POP: | | VVI: | | OSA: | | DOSA: | | BDI: | | SBI: | | SMO: | | PPP: | | CRE: | | VCN: | | CME: | | SCE: | | AGO: | | ERC: | | KLA: | | LTH: | | PPA: | | VPO: | | ZRO: | | CGR: | | NCS: | | NDI: | | TPF: | | TBL: | | TDL: | | KAF: | | DHA: | | PIC: | | PGU: | | LEL: | | CAL: | | CTP: | | CDU: | | COT: | | YLI: | | CLU: | | NCR: | | SMP: | | PAN: | | TTT: | | MTM: | | MGR: | | FGR: | | NHE: | | VAL: | | SSL: | | BFU: | | ANI: | | NFI: | | AFM: | | AOR: | | ANG: | | AFV: | | ACT: | | PCS: | | CIM: | | CPW: | | PBL: | | URE: | | ABE: | | TVE: | | AJE: | | PNO: | | PTE: | | ZTR: | | TML: | | SPO: | | PPL: | | CCI: | | SCM: | | UMA: | | MGL: | | PGR: | | NGR: | | DDI: | | DPP: | | TGO: | | TET: | | PTM: | | TCR: | | LMA: | | LIF: | | LDO: | | LMI: | | LBZ: | | PIF: | |
» show all
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| Reference |
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| Authors |
Elting JJ, Chen WW, Lennarz WJ. |
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| Title |
Characterization of a glucosidase involved in an initial step in the processing of oligosaccharide chains. |
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| Journal |
J. Biol. Chem. 255 (1980) 2325-31. |
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| Organism |
Rattus norvegicus [GN: rno] |
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| Reference |
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| Authors |
Grinna LS, Robbins PW. |
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| Title |
Glycoprotein biosynthesis. Rat liver microsomal glucosidases which process oligosaccharides. |
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| Journal |
J. Biol. Chem. 254 (1979) 8814-8. |
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| Organism |
Rattus norvegicus [GN: rno] |
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| Reference |
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| Authors |
Kilker RD Jr, Saunier B, Tkacz JS, Herscovics A. |
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| Title |
Partial purification from Saccharomyces cerevisiae of a soluble glucosidase which removes the terminal glucose from the oligosaccharide Glc3Man9GlcNAc2. |
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| Journal |
J. Biol. Chem. 256 (1981) 5299-603. |
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| Organism |
Saccharomyces cerevisiae [GN: sce] |
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| Reference |
|
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| Authors |
Grinna LS, Robbins PW. |
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| Title |
Substrate specificities of rat liver microsomal glucosidases which process glycoproteins. |
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| Journal |
J. Biol. Chem. 255 (1980) 2255-8. |
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| Organism |
Rattus norvegicus [GN: rno] |
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| Reference |
|
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| Authors |
Michael JM, Kornfeld S. |
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| Title |
Partial purification and characterization of the glucosidases involved in the processing of asparagine-linked oligosaccharides. |
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| Journal |
Arch. Biochem. Biophys. 199 (1980) 249-58. |
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| Organism |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 78413-07-7 |
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