KEGG   ENZYME: 3.2.1.128Help
Entry
EC 3.2.1.128                Enzyme                                 

Name
glycyrrhizin hydrolase;
glycyrrhizinate beta-glucuronidase;
glycyrrhizin beta-hydrolase;
glycyrrhizinic acid hydrolase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
glycyrrhizinate glucuronosylhydrolase
Reaction(IUBMB)
glycyrrhizin + H2O = beta-D-glucuronosyl-(1->2)-D-glucuronate + glycyrrhetinate [RN:R03906]
Reaction(KEGG)
Substrate
glycyrrhizin [CPD:C02284];
H2O [CPD:C00001]
Product
beta-D-glucuronosyl-(1->2)-D-glucuronate;
glycyrrhetinate [CPD:C02283]
Comment
The enzyme from Aspergillus niger is specific for the hydrolysis of the triterpenoid glycoside glycyrrhizin from roots of Glycyrrhiza sp.
History
EC 3.2.1.128 created 1989
Reference
1
  Authors
Muro, T., Kuramoto, T., Imoto, K. and Okada, S.
  Title
Purification and some properties of glycyrrhizinic acid hydrolase from Aspergillus niger GRM3.
  Journal
Agric. Biol. Chem. 50 (1986) 687-692.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
102484-56-0

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